Alzheimer’s disease is a disease which destroys memory as well as other important mental processes. It is a progressive disease that slowly worsens over time (2). This disease has multiple forms, early onset Alzheimer’s disease and late onset Alzheimer’s disease. Early onset Alzheimer’s disease is generally caused by genetic mutations on genes on specific chromosomes. Late onset disease is not always caused by genetic defects, but genetic factors can increase the risk for this type of Alzheimer’s disease. Before explaining the genetic connections to Alzheimer’s, let’s not forget to discuss what Alzheimer’s is, its symptoms, and the results it has on individuals suffering from it. This disease causes dementia more frequently than anything else. Dementia causes problems w...
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(2) Alzheimer’s Disease. Mayo Clinic. Retrieved March 23, 2013 from:
(3) What are mutations and how do mutations occur? Genetics Home Reference. Retrieved March 23, 2013 from:
(4) Chen, Y-C et al. Sequence Variants of Toll Like Receptor 4 and Late-Onset
Alzheimer’s Disease [Electronic Version]. PLoS ONE 7:12; 2012.
(5) Jin, Sheng Chih et al. Pooled-DNA sequencing identifies novel causative variants
in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer’s
disease Ibero-American cohort [Electronic Version]. Alzheimer’s Research
and Therapy 4:34; 2012.
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