The symptoms of NVP peak during embryonic organogenesis (weeks 6-18) because this is when the embryo is most susceptible to chemical disruption (Flaxman & Sherman, 2000). Organogenesis is the period of organ formation from the tissue layers ectoderm, mesoderm and endoderm. Physically expelling out intolerable foods and feeling nausea are the obvious signs of NVP. Commonly known as a short-term sickness designed for a long-term benefit, NVP begins...
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Tierson, F. D., Olsen, C. L. & Hook, E. B. (1986) Nausea and vomiting of pregnancy and association with pregnancy outcome. American Journal of Obstetrics and Gynecology. 155 (5), 1017-1022.
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Watkins, A. J., Ursell, E., Panton, R., Papenbrock, T., Hollis, L., Cunningham, C., Wilkins, A., Perry, V. H., Sheth, B., Kwong, W. Y., Eckert, J. J., Wild, A. E., Hanson, M. A., Osmond, C. & Fleming, T. P. (2008) Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease. Biology of Reproduction. 78 (2), 299-306.
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