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Short history of mri
Short history of mri
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** Presentation of fMRI technique by scientific expert witness Chris DiFiore for the trial of defendant Jimmy Moran.
Ladies and gentlemen of the juror, in order to understand the power and limitations of fMRI, you must first apprehend the basic principles of magnetic resonance imaging (MRI). The use of MRI has become a standard piece of equipment for Radiology by providing high-resolution images that demonstrates contrast between different types of tissues. It has the ability to diagnosis problems such as tumors, bleeding, tissue damage, and can provide additional information from other commonly used scans such as CT scans and X-Ray’s.
In regards to its mechanism of operation, the physical aspect is fairly complex. The MRI scanner contains an electro-magnet that is capable of producing a magnetic field over 50,000 times that of Earth’s (1). When normal internal randomly oriented hydrogen nuclei are exposed to this field, they are forced to align with the field’s direction. As the nuclei are lined up, a magnetic radio frequency pulse is applied. At the right frequency, these small hydrogen nuclei absorb energy and produce a faint signal that is large enough to measure. The resultant image is the distribution of this faint signal that is altered by the timing of the radio frequency pulses. This allows a structural brain image to be formed. (2)
Furthermore, it is important to not confuse the type of image a basic MRI produces. The MRI produces a structural image that reveals the anatomy of a subject’s brain. What we are interested in is the functionality and areas of activity of the brain; this is the job of the functional magnetic resonance imaging (fMRI) machine. The fMRI is a relatively newly developed technique that uses b...
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...itness is lying, if a witness was at the crime scene, if the defendant feels remorse, or any other courtroom associated question. The possibilities could be endless as the advancement of this technology develops.
Works Cited
Devlin, Hannah. "What Is Functional Magnetic Resonance Imaging (fMRI)? | Psych Central." Psych Central.com. PsychCentral, 30 Jan. 2013. Web. 06 Dec. 2013.
(2) Shin, David, Dr. "What Is FMRI?" What Is FMRI? UC San Diego School of Medicine, n.d. Web. 06 Dec. 2013.
(3) Miller KL, Hargreaves BA, Lee J, Ress D, de Charms CR, Pauly JM. Functional brain imaging using a blood oxygenation sensitive steady state. Magn Reson Med.2003;50:675–683.
(4) Lindquist M The statistical analysis of fMRI data. Stat Sci 23: 439–464,2008.
(5) Miller, Greg. "FMRI Evidence Used in Murder Sentencing." Science/AAAS. Science Insider, 23 Nov. 2009. Web. 06 Dec. 2013.
My interest in MRI started when I first read the book “MRI, The Basics” written by the author Ray Hashemi. By the time I successfully finished my MRI clinical placement in Tehran University of Medical Sciences, I knew for sure that MRI would be the field I would be choosing to take on. What attracts me most about MRI is how beautifully scientist could create a technology that can take advantage of the magnetic moments of human body for imaging it without any harms of ionizing radiation. Although there are drawbacks to MRI, combining it with other modalities would be a more effective approach to an accurate diagnosis.
Other testing procedures that are commonly employed, in order to gain a better visual image of the excitatory activity in the brain are the PET scan and the MRI. According to Kalat (2004), these methods are non-invasive, meaning that they don’t require the insertion of objects into the brain, yet they yield results that allow researchers to record brain activity. The PET scan (positron emission tomography) involves the researcher injecting a radioactive chemical into the patient’s body, which is then absorbed mainly by the brain’s most active cells. With the use of radioactive detectors, placed around the patient’s head, a map is produced that shows which areas of the brain are most active.
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“What Is a Concussion?” What Is a Concussion? | Brain Injury Research Institute, www.protectthebrain.org/Brain-Injury-Research/What-is-a-Concussion-.aspx. Accessed 30 Jan. 2018.
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In both clinical care and research, the use of brain imaging, also known as “neuroimaging”, is becoming an increasingly important technique. New technologies such as Functional Magnetic Resonance Imaging, or FMRI, allow researchers to study the brain at a level which was never thought possible. This noninvasive procedure allows researchers to visualize brain structure and function, at both the molecular and whole brain level (A.) Scientists are now able to better understand neural networks and a variety of other cognitive processes. For the first time in human history, extremely complex wonders of the brain are being uncovered. Psychiatric diseases, human emotion, personality traits, and many other phenomena that were once mysteries are now being deeply analyzed and understood. Each day new doors are being opened...
Raine, Adrian, Monte Buchsbaum, and Lori LaCasse. "Brain abnormalities in murderers indicated by positron emission tomography." Biological psychiatry42.6 (1997): 495-508.
As previously stated, neuroimaging science and study began in the early 1900s. The “great granddaddy” of functional brain viewing is electroencephalography, or EEG, and was invented by a German researcher by the name of Hans Berger. This exceptional neurologist discovered that the electrical activity of the brain is detectable outside the head. Following Berger’s steps, a group of scientists came up with ...
Obstructions such as tumors can interrupt normal brain activity, leading to deficits of normal reasoning, motor control, or consciousness. Many of the signs of neural damage are easily recognizable by an outside observer, but since the actual cause of these problems are internal, the symptoms can be vague. The real deficits can affect the brain’s anatomy, or the way signals are processed. A physician can only determine the real cause by examining the brain internally to find irregularities, either in structure or in functioning.
The brain is arguably the most complex part of a human being and is linked to motivations, feelings, and actions. Therefore, when actions of individuals differ from “normal” actions, the brain is brought into question. Repeat killers commit actions that are not “normal” when compared to the general public and therefore research on their brains has been conducted. When comparing scans of everyday citizens’ brains as opposed to the brain of a convicted serial killer, the differences are clear. The two scans differ widely with the prefrontal gray matter of the average person’s, dwarfing that of the murderer’s (Adams). Pr...
Greenfield, D. (2007). Introduction to forensic psychology. issues and controversies in crime and justice. Journal of Psychiatry & Law, 35(2), 201-201-204,105-106.
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