Thalidomide Research Papers

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The use of medication by pregnant women has increased over the past thirty years. This is a surprising statistic given the fact that medication is known to cause birth defects. Researchers have recently published a study describing medication use during pregnancy in the United States from 1976-2008. Data from their study revealed that the majority of pregnant women took at least one prescription drug during pregnancy. 50% of women in the study reported taking at least one prescription medication while 70-80% reported taking at least one over the counter medication. Also, during the first trimester of pregnancy the use of prescription medications have increased by more than 60% (Centers for Disease Control and Prevention). This study emphasizes the need for further education and research on the safety of medication used during pregnancy. According to the Center for Disease Control, “taking certain medications during pregnancy can cause serious birth defects” (Center for Disease Control and Prevention). Consumption of medications, such as Thalidomide, during pregnancy may result in negative effects to the unborn child.
Taken during pregnancy, thalidomide was said to ease morning sickness. Manufactured by Chemie Grunenthal of Germany in 1957, thalidomide was sold over the counter by prescription (Burkholz). According to James Jones of the Health WorldNet, “Thalidomide was used in over fifty countries and was the cause of uncountable miscarriages, still births, and over twelve thousand ‘flipper babies’ “ (James Linder Jones). According to Frederick Dove of BBC News, many women took thalidomide and were “utterly unaware its effects on the unborn child” (Dove). In 1961 a connection between the use of thalidomide and an increase of se...

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...that relax the uterus and stop contractions. These “tocolytic” medications allow the baby to remain inside the uterus and mature which reduce the risk of long-term mental and physical disabilities (Mayo Clinic) (Edmund F. Funai).
A pregnant woman needs to be careful taking medicine, especially known tocolytics such as thalidomide, because they may result in negative effects to the unborn child. Category X, D, and C drugs pose a substantial risk to an unborn child and should not be used during pregnancy. Category B and A drugs can be used relatively safely under the direction of a physician. There are even a few situations where medications may actually help an unborn child. The question of taking medications during pregnancy is something important to discuss with a doctor. Taking medications during pregnancy is a controversial topic and further research is needed.

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