Paranoid Schizophrenia Summary

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There are many origins to consider in regards to paranoid schizophrenia. The illness develops as a result of interplay among genetic predispositions and environmental stressors. The prominent cause lies within the genes during pregnancy and early childhood, leading to subtle alternations within the brains chemistry, which in turn makes the individual more susceptible to the illness. Conversely, environmental stressors that arise later in life can damage the brain further and increase the risk.
Although heritability is often accentuated, onset for the movie client is associated with two environmental stressors: social anxiety and tobacco smoking. To an important degree, these behaviours work hand in hand with respective genetics; the stressors …show more content…

Mr. Nash had a difficult time participating in a game of chess with his friend while being surrounded by many other students. The inability to focus was apparent, as Mr. Nash would fidget and shutter his words throughout the game. He exclaimed that he felt an abundance of stress and pressure. Researchers suggest that environmental social stress may have a “greater impact on affective and psychotic dimensions” which includes delusions and hallucinations (Van, Kenis, & Rutten, 2010, p. 204). Social anxiety makes delusions worse and the individual is paranoid of their surroundings as a result. More exposure to these types of settings results in progressively greater risk of paranoia. The origin then becomes a problem within itself after the diagnosis has been made. Psychotic dimensions lead to higher dysregulation of social conflict and cognitive symptoms through reduced social competence (Van et al., …show more content…

For example, moving to a more urban society such as Princeton University creates more social anxiety. Mr. Nash experienced his symptoms upon arrival at Princeton. Perhaps he had a specific gene that become more susceptible when turned on by a different environment? Interestingly, the interaction of BDNF and NTRK2 genes polymorphisms in ongoing stressful situations show a direct correlation with paranoid schizophrenia (Lin et al., 2013). Social stress during early adult years leave the brain sensitive to chemical and genetic alternations. Researchers suggest that there is a specific gene associated with social anxiety; it is formerly known as gene 5-HTT and referred to as the shy gene (Van et al., 2010). This particular gene has been linked to anxiety, creating a disturbance within the amygdala which is a center in the brain responsible for processing emotions such as fear. Mr. Nash demonstrated fear when arriving at social functions, allowing his brain sensitivity to increase due to the uncontrollable state of mind. Thus, sensitivity allowed for alternations in the brain

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