GENERIC NAME: naloxone hydrochloride
BRAND NAME: Narcan, Evzio
Naloxone [Narcan] is a structural analog of morphine that acts as a competitive antagonist at opioid receptors, thereby blocking opioid actions. Naloxone can reverse most effects of the opioid agonists, including respiratory depression, coma, and analgesia (Lehne, 2013). Naloxone may be administered IV, IM, Intranasal, or subQ. Following IV injection, effects begin almost immediately and persist about 1 hour. Following IM or subQ injection, effects begin within 2 to 5 minutes and persist several hours (Lehne, 2013).
Use of naloxone may cause symptoms of opioid withdrawal, including (Naloxone, 2016):
• Feeling nervous, restless, or irritable
• Body aches
• Dizziness or weakness
• Diarrhea,
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This is being done in hopes to decrease the number of overdose deaths that are occurring in West Virginia. The law does have restrictions. Those who buy naloxone OTC must be trained by a pharmacist on how to recognize an overdose, when to administer the antidote, and how to properly inject or inhale the drug. Pharmacies must also provide educational material telling customers how and where to access treatment programs (Brown, A., Para. 1, 2016). West Virginia being the number one state in overdose deaths, I personally believe that it is a good decision to pass this law. However, I think people should be trained properly on how to administer, when to administer, what to do, what signs to look for and how to respond. Narcan is a life savior and it should be readily available over the counter. Just because they have addiction or uses drug, they don’t deserve to die. If there is already a drug to save someone’s lives, why not use it. It is ridiculous how expensive the drug cost compared to other countries. Lower class and middle class people cannot afford to buy a drug for 500 to 600 dollars. I think it is a control by the big drug industries to make more money but being greedy is just hurting everyone. If country like Australia and Canada can sell cheap as a dollar, how come it costs 500-600 dollars in USA. People have stereotype belief that only druggies gets overdosed. However, it is not true. Older people who sometimes forget what medicines they took, light weight people who had never taken any drugs when started on pain medicines because of accidents or even though if it is overdose by someone trying to get high, saving life is a miracle. With the scientific achievement, people can make clone, skin graft, synthetic valves or many ways to save or repair human body, but no one can bring a soul back to a dead body. Many people doesn’t get overdosed to kill
1Fentanyl is a powerful synthetic opiate analgesic, which has a primary function in managing malignant and non-malignant contractible pain, similar to morphine however it is more potent. This is because fentanyl has an octanol-water partition of 9550 compared to morphine, which has 6. This effectively demonstrates that fentanyl is highly lipid soluble, crossing the blood brain barrier more rapidly. Hence it has a quicker reaction time but at a shorter duration compared to morphine. It is commonly used to treat patients with severe pain or patients experiencing pain after a surgery. Fentanyl can also be used to treat patients with chronic pain that are physically tolerant to opiates. Patients who are not physically tolerant to opiates should avoid the use of fentanyl as this can cause undesirable side effects, which can in some cases be toxic. Fentanyl is registered as a class II prescription drug, meaning that it has a greater potential for being abused, which could have negative implications on a patient’s health as it can result in psychological or physical dependence.1
...n overdose mortality after the opening of North America'ss first medically supervised safer injecting facility: a retrospective population-based study. Lancet, 377(9775), 1429-1437.
As of today this type of treatment is one of the most widely known options for clients who have opiate issues. This treatment is a combination of two different drugs: buprenorphine and naloxone. Buprenorphine is a lower form of opiates that is given to the patient with opiate addictions because it provides them with fewer side effects when coming off the addiction. Naloxone is a blocker medication that is primarily given in emergency rooms to individuals who have overdosed wit...
In 1906, the Pure Food and Drug Act, that was years in the making was finally passed under President Roosevelt. This law reflected a sea change in medicine-- an unprecedented wave of regulations. No longer could drug companies have a secret formula and hide potentially toxic substances such as heroin under their patent. The law required drug companies to specify the ingredients of medications on the label. It also regulated the purity and dosage of substances. Not by mere coincidence was the law passed only about five years after Bayer, a German based drug company began selling the morphine derivative, heroin. Thought to be a safe, non-habit forming alternative to morphine, heroin quickly became the “cure-all drug” that was used to treat anything from coughs to restlessness. Yet, just as quickly as it became a household staple, many began to question the innocence of the substance. While the 1906 law had inherent weaknesses, it signaled the beginning of the end for “cure-all” drugs, such as opiate-filled “soothing syrups” that were used for infants. By tracing and evaluating various reports by doctors and investigative journalists on the medical use of heroin, it is clear that the desire for this legislative measure developed from an offshoot in the medical community-- a transformation that took doctors out from behind the curtain, and brought the public into a new era of awareness.
Various pharmaceutical companies are resisting the changes by lobbying against the legislation that requires a prescription. This was the second most disturbing part of the video to me because these companies care far more about money and profits than the wellbeing and safety of the American people. This documentary offers a plan of action to take in reducing the number of meth-related crimes and incidents in the United States. Other states should follow Oregon’s model by making legislation that requires.
Opioid’s chemical composition consist of many highly addictive substances which cause the human body to become quickly tolerant. Many opioid users become addictive to the substance because the doctors have been over prescribing. “In the United States, there were 14,800 annual prescribed opioid (PO) deaths in 2008” with the US having less restrictions (Fischer, Benedikt, et al 178). The United States have implemented more regulations so that “high levels of PO-related harms been associated with highly potent oxycodone formulas” will decrease (Fischer, Benedikt, et al 178). With the regulations, it does not change the fact that opioids are is destructive. The regulations assistance by lessening the probability of patients becoming addictive to opioid. There are numerous generations that are effected and harmed by the detrimental effects of opioids on opioid-dependent patients.
On September 21, 2016, I attended my first Narcotic’s Anonymous (NA) meeting at Cana Lutheran Church. Before attending this meeting, I had some preconceived views on what an ordinary NA meeting might be like. I originally thought of the meeting only as a group of individuals seated in a circle while sharing their feelings. I imagined that these people might be forced to attend the meeting by a spouse or some other influence in their lives. However, I was certainly mistaken. This meeting was much more; in fact, it is an essential part of the recovery process for many.
Narcan is a drug used to reverse the effects of opioids, specifically the effects on breathing. When a person overdoses on opioids, such as heroin and some pain medications, their breathing slows and may even stop, potentially causing damage to their brain due to the lack of oxygen. Narcan reverses the opioid effects, allowing the person to breathe again, but also taking away the high. Some people who recover from the overdose too quickly become agitated and “come out swinging”. That is the danger EMTs face when administering Narcan.
During the same period, four states passed laws against assisted suicide that did not include language affirming pain control like that found in the federal Pain Relief Promotion Act. Even here, there is little evidence of a significant "chilling effect" on morphine use; but per capita use of morphine tended to stay about the same or to increase only slightly. In these four states, where new bans on assisted suicide lacked the kind of positive language on pain control found in the Pain Relief Promotion Act, morphine use rose by an average of 3%.
The fact that safe injection sites exist should be against the law in some way. If having possession of a drug is illegal, then going to a safe injection site should be illegal. Opioid addiction is a decision, when someone does an opioid drug they are not only breaking the law, but they are putting their life and possibly other people’s
Morphine is a highly addictive opiate psychoactive painkiller. It is often used before or after surgery to alleviate severe pain. Morphine acts by attaching to specific proteins called opioid receptors, which are found in the brain, spinal cord, and gastrointestinal tract. The drug was originally derived from the poppy seed plant before it was chemically enhanced and manufactured. Starting off, the drug was used to cure alcoholism and certain types of addictions.
...ctive drugs for the pharmacotherapy to treat opioid addiction. However, these drugs are addictive and will take some time for an individual to slowly stop using them and prevent withdrawal symptoms.
Substance addiction is becoming an epidemic. While some people can quit using a substance without any help, most people need help to their recovery. Narcotics anonymous is an important support group for our society. There are many different narcotic anonymous programs to join that have meetings throughout the week. The members of the support group all share one thing in common, they suffer from different types of chemical dependency. Members help each other because they have the same problems and worries that everyone in the room has. Though they may be struggling with different stages in their life, for the most part, they all relate to what each is going through. Just as AA, NA focuses on the 12-step program. The members of
Dobler-Mikola, A. Gschwed, P. Gutzwiller, F. Steffen, T. Rehm, J. Ucthengagen, A. (2001) Fesaibility, Safely, and Efficacy of Injectable Heroin Prescription for Refractory Opioid Addicts: a follow-up study. The Lancet, volume 358, pg 1417-1420
West Virginia has one of the highest rates for prescription drug abuse, and overdose in the nation. In order to change this it is important to understand what pharmacists do, their role in prevention, and the severity of prescription drug abuse. Pharmacists are known to dispense prescription drugs to patients and inform them about their use; However, one aspect of their career most people overlook is that Pharmacists must keep a sharp eye out for criminals looking to abuse these prescribed drugs.