Loxo Executive Summary

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Regarding the business strategy of Loxo, the company aims to, “develop a pipeline of highly selective drugs that inhibit oncogenic drivers in cancer” (Loxo 1) as stated on their website. Since these genetically defined cancers affect each patient differently, the goal is to establish a general therapy that would be strong enough to fight the tumors and make any changes if necessary. Their treatments are patient-focused, as the therapy will build selective inhibitors to fight the drivers, which can vary from each case. Loxo’s goal is to have its therapy available to as many patients as possible, as seen with the partnership with the international company Bayer. The partnership also improves their research and development, something Loxo strives …show more content…

On April 10th, 2018, the company announced a partnership with genetic testing company Illumina Inc. on a diagnostic tool that will work with Loxo’s larotrectinib that will allow, “local laboratories to provide referring physicians with comprehensive genomic information” resulting in a, “sequencing-based companion diagnostic with a pan-cancer indication” (Reuters 1). This relationship would allow for patients to matched to the proper therapy better, as the combination of the two’s work would lead to better research that would be used for treatment. It improves upon Loxo’s current R&D as their technology has advanced due to the combination of the diagnostic and the indicator for fighting the driver of the patient’s cancer. The following day, Loxo announced a partnership with Veracyte where they will use its, “RNA sequencing-based assay to assess TRK fusions and RET alterations in thyroid cancers” (Genomeweb 1). This partnership will improve the company’s R&D by providing a thorough database containing information on thyroid cancer that will advance its pipeline. These two deals are vital in the improvement to the R&D of Loxo, as they are able to advance their technology and information to determine which form of therapy is

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