Helicobacter Pylori Research Paper

Prevalence of Helicobacter Pylori Infection and Histologic Gastritis in Asymptomatic Persons

This research was done by Cornelius P. Dooley, Hartley Cohen, Patrick L. Fitzgibbons, Madeline Bauer, Maria D. Appleman, Guillermo I. Perez-Perez, and Martin J. Blaser. It was done at the Departments of Medicine (C.P.D., H.C., M.B.) and Pathology (P.L.F., M.D.A.), Los Angeles County-University of Southern California Medical Center, and the Medical Service, Veterans Administration Medical Center Denver (G.I.P. P., M.J.B.), the Section of Gastroenterology, Department of Medicine, USC School of Medicine, 2025 Zonal Ave., Los Angeles, CA 90033. It was presented in part at the 89th annual meeting of the American Gastroenterological Association, New Orleans, LA.

The overall purpose of this experiment was to estimate the prevalence of Helicobacter pylori, which is formerly called Campylobacter pylori, infection and histologic gastritis in asymptomatic individuals. It was done by using endoscopic biopsy of the gastric antrum and corpus.

pylori infection commonly occur in the stomach of apparently normal people. In addition, they increase in prevalence with advancing age. The effect of age did not reach statistical significance of the H. pylori, and the prevalence of gastritis increased significantly with advancing age. This study showed that all the individuals with H. pylori infection had gastritis, suggesting a possible etiologic role for the bacterium in the histologic lesion. This study is significant to science and to humanity because it will help people to understand that H. pylori bacteria are found in people’s stomach without showing any signs of their presence. There are some questions left to be answered in this study. First one is that would the outcomes be different if younger individuals were studied? Second, would the statistics be different if different group of people such as middle eastern were