Green Tea Catechins Case Study

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A large number of hand sanitizers are available in the market having various chemical agents and effectively kill the microbes. The problem with these is skin allergy and destruction of normal skin flora as well. These normal flora constitute host defense mechanism against pathogenic microbes as in their presence pathogenic organisms have difficulty in multiplying effectively. Hence suppression of skin normal flora by chemical hand wash antiseptics may lead to compromised skin defense mechanism so pathogens grow and may cause disease. Ideally hand wash antiseptic should kill only the pathogenic microbes with little and repairable damage to normal flora. For this purpose green tea catechins were tested on an experimental skin contact model for influenza virus transmission by using green tea solution as a first-hand disinfectant and found to be highly effective in eradicating the virus from the skin cell layer. The skin model may be used for developing safe non-pharmaceutical preparations having minimum damage to skin (Shin et al., 2012).
Teas (green and black) are also found to be effective against a large number of viruses including rotavirus, Herpes simplex virus, HIV, enterovirus, Epstein Barr virus, plant virus like tobacco mosaic virus and green tea catechins play an important role in its antiviral properties (Yiannakopoulou, 2012). Due to zoonotic nature of infectious diseases, the use of green tea in both humans and livestock may reduce the incidence of animal to human transmission helping the control of spread of infectious diseases.
Green tea catechins show broad spectrum antimicrobial activity by acting on specific targets for different pathogens such as microbial cell membranes. It also shows activity against enveloped ...

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...howing its disease inhibitory effects in HCV infection.
Constituents of a unique nutrient mixture, containing ascorbic acid, green tea extract, lysine, proline, N-acetyl cysteine, selenium have been shown to inhibit the replication of influenza A virus and human immunodeficiency virus in infected cells and also the neuraminidase activity (NA) in virus particles in vitro. Viral nucleoprotein synthesis in infected Vero or MDCK cells can be inhibited by the components of nutrient mixture like ascorbic acid and green tea extract when used in combination (Jariwalla et al., 2007). This nutrient mixture is also effective against A/H5N1 strain of avian influenza virus and inhibits the replication of HIV as well even at the late stages of infection. Antiviral activity is comparable to the commonly available antivirals like oseltamivir and amantadine (Deryabin et al., 2008).

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