Cor Pulmonary Disease: A Case Study

Associated Comorbidities

Patients with advanced COPD are prone to develop secondary complications of the disease. The goal of treatment is to restore functional status as quickly and as much as possible and to alleviate distress and discomfort. The main diseases associated with pulmonary arterial hypertension are that anemia Osteoporosis and coronary heart disease. Cor Pulmonale refers to altered structure or function of the right ventricle, resulting from pulmonary hypertension (PH) associated with chronic lung disease In the course of COPD endothelial dysfunction occurs in the pulmonary artery, which has a decreased secretion of Vasoactive mediators such as nitric oxide and Prostacyclin come, this leads, also enhanced by the hypoxia to

That increased incidence of osteoporosis can be besides associated, spread Lifestyle characteristics such as inactivity, poor diet and smoking, especially through the systemic inflammatory response and treatment of COPD explain. Here, in addition to a lead Variety of other mechanisms, Proinflammatory cytokines, such as TNF-α, for Stimulation of Osteoclast differentiation and activation, and thus to an increased Bone resorption [70]. A systemically important therapy with Glucocorticoid given an appropriate time activity by influencing the Osteoblast replication and which Induction of apoptosis in Osteoblasts and Osteocytes and the promotion of Osteoclast proliferation to a glucocorticoid-induced osteoporosis lead. Since the presence of osteoporosis, the probability of fractures, especially for Vertebral compression fractures, and these increases, even if they are asymptomatic, have significant influence on the performance and the drop in pulmonary function and thus also to the frequency of exacerbations, it is important at an early stage of osteoporosis diagnosis and therapy performed, so the complication of the systemic disease of COPD counter [71]. Ischemic cardiovascular disease is a leading