I herewith submit my application for consideration of term tenure appointment. I am currently a Professor in the Department of Cellular and Molecular biology. The late Dr. Allen Cohen, Executive Director of Research, UT Health Center at Tyler, first recruited me as an Assistant Professor of Molecular Biology in August 1990 to work on lung surfactant protein gene regulation. I was promoted to Associate and Full Professor ranks in 1995 and 2004, respectively. Briefly, I obtained my Ph. D. in Biochemistry from the University of Stockholm, Sweden, working under the mentorship of Dr. Bengt Mannervik, a world leader in the field of enzymes that metabolize glutathione. After obtaining my Ph. D., I conducted postdoctoral research, first on cytochrome P-450 gene regulation and then on surfactant protein gene regulation in the …show more content…
My research on surfactant protein gene regulation centered on the elucidation of molecular mechanisms of developmental, hormonal, and cytokine regulation of surfactant protein gene expression. Highlights of my research on surfactant protein gene regulation include: the discovery of a major role for posttranscriptional (mRNA stabilization) regulation in the control of developmental and hormonal induction of surfactant proteins B and C; identification of genomic regions that direct cell/tissue-specific expression and developmental regulation of surfactant protein B; discovery of thyroid transcription factor-1 (TTF-1) as a key target in the down regulation of surfactant protein B gene expression by inflammatory mediators such as ceramide, nitric oxide and TNF-alpha. I narrowly missed renewed NIH funding due to cut backs and very low pay lines at that time. However, I was successful in obtaining funding for a new project, started in collaboration with Dr. Jeff Levin, Department of Occupational and Environmental Health Sciences, from the National Institute of Occupational Safety and Health
Pubmed.com. Web. The Web. The Web. 26 Nov. 2013.
38. Elsevier. Shaw, Jessica, Tanya Basok, Jeffrey Noonan, Suzan Ilcan, Nicol A. Noel. 2013. The.
Stetson Charlotte Perkins. The Yellow Wallpaper. United States National Library and Medicine Bathesole, Maryland. 647-656.Ret. 11 Feb. 2014. {nlm.nih.gov}
Grigg, Bill. “NIH News Release.” 28 Dec. 1999 [last revision]. < <a href="http://www.nih.gov/news/pr/dec99/niehs-28.htm">http://www.nih.gov/news/pr/dec99/niehs-28.htm > 1999.
Segal, E. A., Cimino, A. N., Gerdes, K. E., Harmon, J. K., & Wagaman, M. (2013). A
My current area of interest is in the engineering and the biomedical field. After experiencing the rigorous AP Chemistry course, I was able to find my passion in the field of medicine. Furthermore, I had already developed an interest in engineering from my previous engineering courses and clubs, so a deeper understanding of what I wanted to do was discovered in a chemistry lab. Being involved with the Technology Student Association at our institution, I learned several different skills in a variety of technical fields. This led to my conclusion that I wanted to become a biomedical engineering. This field of engineering incorporates both the medical aspect and technical aspect of what I want to become in the future.
My assignments include Principal Investigator, Deputy Chief, Research Division, and Chief Pharmacology Branch at the U.S. Army Medical Research Institute of Chemical Defense. I also served as the Officer in Charge of Quality System and Regulatory Compliance Office at US Army Public Health Command. In 2014, I became the Chief of Method Development and Molecular Biology Sections. At present, I am the Medical Product Manager of the Neurotrauma and Psychological Health PMO of the US Army Medical Material Development Activity.
The nominees who qualify for this award are those who have made major scientific contributions and seminal discoveries that are interpreted as significant and original biomedical science achievements. The five recipients of this award are scientists who have made outstanding discoveries and significant contributions to medical science. It is important to note that a lifetime body of work is not necessarily considered as a nomination criterion for this award. The nominees are then evaluated based on the quality of their research as submitted to the foundation.
CORE COMPETENCIES • PhD in Biochemistry from University of Toronto with 3 years of Postdoctoral experiences in academic and industrial settings, such as GlaxoSmithKline Biologicals and Industrial Biodevelopment Laboratory, in the field of Immunology and Cell Biology • Holding a certificate in Business Development • Ability to communicate and write in three languages: English, French and Persian • Extensive and in-depth medical knowledge in multiple therapeutic areas in specific Oncology (prostate, breast and ovarian Cancer and brain tumor), Hematology, Vaccine (Immunology), Rare diseases (Tay-Sach's, Sandhoff disease and Mucolipidosis II and III), Diabetes, and Neurodegenerative disease (Alzheimer’s disease) • Publications in peer-reviewed
My exploration of medicine began as I grew up shadowing my father, who is a medical physicist. I became fascinated with the advances in medicine that bring phenomenal care to those that need it. My interactions with other physicians drew me closer to the profession as I observed their character, lifestyle, and the service they provided to people each day. As I thought of how I could contribute to society for the rest of my life, nothing made me more excited than becoming a physician.
1. Foucault 1991, 1997; Barry et al. 1996; Dean 1999; Inda 2005; Suzana Sawyer and Edmund Terence Gomez 2008;
Murray, R. K. Granner, D. K. Mayes, P. A. Rodwell, V. W. (2003) Harpers Illustrated Biochemistry, Lange Medical Books/McGraw-Hill Medical Publishing Division
...ional Center for Biotechnology Information. U.S. National Library of Medicine, 24 Jan. 2014. Web. 24 Apr. 2014.
Biology to me is far more than the study of life and living organisms. To me it is the intricate act of taking the fundamentals of life and using these elements to create extensive connections, generating clarification on theories regarding how all life is able to exist and adapt. I believe the subject of biology is so much more than the A-Level textbook I am currently studying, but a whole world of research and new innovative opportunities, with breakthroughs that can change people’s lives. It is this premise and the ever changing world of science that has fuelled my enthusiasm for biology over the duration of my school years. I first became fascinated with the subject during my first year of fast track GCSE biology lessons.
Ronald M. Epstein, M., & Edward M. Hundert, M. (Downloaded from www.jama.com by guest on August