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Amyotrophic lateral sclerosis research paper
Amyotrophic lateral sclerosis research paper
Amyotrophic lateral sclerosis research paper
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Neurodegenerative diseases are characterized by the presence of protein aggregations with a varying protein content depending on the type of disease formed. One of the prime diseases resulting from protein inclusion bodies (aggregations) is Amyotrophic Lateral Sclerosis (ALS), which was the broad scheme of focus throughout this study (NIH 2017). ALS is a fatal neurodegenerative disease that causes death of motor neurons in the motor cortex, brainstem and spinal cord, as well as peripheral skeletal muscles (first in the limbs, then progressively beyond those distal extremities). This leads to motor problems, muscle weakness, and paralysis. These motor impairments are gradually progressive, and therefore ALS is usually fatal within 3–5 years
According to ALS Association (2016, para. 1), “Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in Amyotrophic Lateral Sclerosis eventually leads to their demise.” When our motor neurons die, our brain can no longer control our muscle movement. The survival time for a person living with Amyotrophic Lateral Sclerosis is up to ten years because eventually a person’s body will shut down completely. According to the Mayo Clinic (2016, para. 2), “As the disease advances and nerve cells are destroyed, your muscles progressively weaken. This eventually affects chewing, swallowing, speaking and breathing.” This disease is very scary to live with because you eventually die from
Neurodegeneration is used mainly for diseases that are characterised by progressive loss of structure and function of neurons. There are many neurodegenerative diseases including amyotrophic lateral sclerosis that...
ALS is a degeneration of motor neurons that move from the brain and down the
Mitchell, J. D. and G. D. Borasio. 2007. Amyotrophic lateral sclerosis. Seminar. 369: 2031- 2041.
…progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. When the motor neurons die, the ability of the brain to initiate and control muscle movement is lost. The progressive degeneration of the motor neurons in ALS eventually leads to [the patients] death (Alsa.org, 2014).
In this essay, the disease Multiple Sclerosis (MS) will be reviewed. This piece of work will lay emphasis on the pathophysiological, psychosocial, economic and cognitive effects it has on the individual, family and society. It will also make mention of how a professional nurse would support the individual, the family/carer, the nursing process and the professional role of the nurse according to the Nursing and Midwifery Council (NMC) code of conduct which sets a standard for all nurses and midwives (NMC, 2008) . It has been chosen because this chronic disorder is quite prevalent in the UK.
A piece of well-oiled machinery consists of an intricate and complex system: there are well-organized processes, mechanisms within the device work efficiently, and multiple processes function simultaneously to subsequently perform various functions. What happens when there is a glitch in the machine? When there is something wrong, such as connections between intricate processes, which do not follow through, the machine fails to function properly. In some cases, there are not any adjustment or fallback mechanisms. At that point, the damage can be irreversible and the machinery is no longer salvageable. [However, this can illustrate the interactions and processes within the complex machinery.]
Amyotrophic lateral sclerosis, or ALS, is a degenerative disease affecting the human nervous system. It is a deadly disease that cripples and kills its victims due to a breakdown in the body’s motor neurons. Motor neurons are nerve cells in the brainstem and spinal cord that control muscle contractions. In ALS, these neurons deteriorate to a point that all movement, including breathing, halts. Muscle weakness first develops in the muscles of body parts distant from the brain, such as the hands, and subsequently spreads through other muscle groups closer to the brain. Such early symptoms as this, however, can hardly be noticed.
Amyotrophic Lateral Sclerosis, otherwise known as ALS, is a disease of the nervous system that controls muscle movement. With ALS, your motor neurons (cells that control muscle cells) are lost. As these are lost, the muscles become weak and eventually will quit working all together.
In the world of neurology, there are a vast amount of neurological disorders, conditions, and diseases. One severe disease is known as Multiple Sclerosis. In this research essay, I will be discussing what multiple sclerosis is, symptoms, causes, personal experience, and treatments.
Imagine if you loss control of your body but your mind stayed unaffected. You would be a prisoner in your own body, all leading up to your death sentence. That is the sad fate for the people diagnosed with Amyotrophic lateral sclerosis (ALS). “Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder was first described by Ran in 1850. This description was then expanded in 1873 by Charcot, who emphasized the involvement of the corticospinal tracts. In the United States, ALS is often referred to as Lou Gehrig's disease, after the famous ball player who was stricken by the disease in the midst of his career. (Yale School of Medicine, 2014)” In this paper will go through the definition, the process, the signs, the risk factors, etiology, and discus the known people that have suffered with this terminal disease.
Amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, is a neurological disorder that affects roughly one in 200,000 people (DiDonato et al., 2003). As such, ALS is among the most common neurological disorders found in humans. It typically occurs mid-life and kills motor neurons, which leads to paralysis and death. Most cases of ALS do not show a genetic linkage. However, five to ten percent of cases are, in fact, inherited in an autosomal recessive manner (DiDonato et al., 2003). This inherited ALS is referred to as familial ALS (FALS), and twenty percent of these cases are connected to mutations in the SOD1 gene.
Imagine being at the best part of your athletic career and suddenly it has to come to an end, because of a diagnosis with Amyotrophic Lateral Sclerosis (ALS) or Chronic Traumatic Encephalopathy (CTE). Even though it is a serious illness many people are still not aware of it, therefore, there aren’t enough funds given to those organizations that help research these diseases. Nobody really know why athletes are at a bigger risk of developing these diseases at an early age but many have came up with their own conclusions. Many people blame sports like football, boxing, and hockey that athletes develop ALS and CTE at an early age. While others believe that sports have no blame and it is just a
Multiple Sclerosis (MS) is a debilitating autoimmune disease. The Central Nervous System (CNS) is attacked by the immune system; creating lesions that interrupt the correct signaling of nerves, spinal cord, and brain (Frankel, & James, 2011). Inhibiting development of this disease is crucial for maintaining quality of life and fatigue for individuals with MS. There has been vast amount of research on the effect of various exercise training programs, and their benefits for MS (Motl, & Gosney, 2008, Krupp, 2003, Chen, Fan, Hu, Yang, & Li, 2013). Balance, aerobic, and strength training have been the main focus of most researchers; causing an interest in what training mode is most effective for improving quality of life and lower fatigue. It is critical to examine and contrast the effectiveness of a variety of exercise programs, because if training is completed effectively it can drastically improve quality of life and fatigue for individuals with MS.
The brain is a very complex organ that requires controlled conditions to ensure that it functions correctly. When these conditions and needs are disturbed the brains functions are altered. Neurodegeneration is a consequence of changes within normal brain physiology. Neurodegeneration is a broad term that is used to describe a group of conditions that is characterised by a loss of structure and function of the neurons within the brain. A few examples of neurodegenerative diseases include Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyotrophic lateral sclerosis (ALS). These neurodegenerative diseases can be caused by many factors some of which include genetics, protein misfolding, changes in intracellular pathways (such as protein