A Close Look at Rheumatoid Arthritis

3766 Words8 Pages

Pathophysiology

RA is a mediated inflammatory process that triggers an autoimmune response. The result is in the production of antibodies and inflammatory cytokines that over time destroys bone, cartilage, tendons, ligaments and blood vessels (Dewing, Setter, & Slusher, 2012). Although joints are the primary areas of destruction, the inflammatory process can also affect various organs, such as heart tissue including the heart values, visceral layers of the lung and brain, spleen, sclera and larynx (Dunphy, Windland-Brown, Porter, & Thomas 2011). If RA is not treated promptly or if the patient does not respond to treatment, irrevocable bone deformity, bone erosion and immobility is often the sequelae.

Standards of treatment

According to the American College of Rheumatology (ARC) (2012) and recommendations by the International Task Force of Rheumatologists (2010) treatment is aimed at remission, reduction of the inflammatory response, pain control, conserving joint function and preventing and/or halting joint destruction. Medications used to treat RA fall into two categories: fast acting and slow acting. Fast-acting medications typically address pain and inflammation. Medications include but are not limited to anti-inflammatory drugs such as aspirin, ibuprofen, Celebrex and corticosteroids such as cortisone and prednisone. Slow-acting medications slow joint destruction and stimulate remission; these medications include DMARDS and biological medication. The mainstay of treatment is the use of DMARDS such as Methotrexate, Plaquenil, and biologics known as TNF inhibitors including infliximab, etanercept and adalimumab. Since the 1970s DMARDs have been the gold standard of treatment (Kahlenberg and Fox, 2011).

The medicat...

... middle of paper ...

... rheumatoid arthritis: a quantitative and qualitative study. BMC Musculoskeletal Disorders, 11(1), 43.

Uhlig, T. (2012). Tai Chi and yoga as complementary therapies in rheumatologic conditions. Best Practice & Research Clinical Rheumatology, 26(3), 387-398.

U. S. Department of Health and Human Services, National Institutes of Health, National Center for Complementary and Alternative Medicine. (2012). Retrieved from http://nccam.nih.gov/about/plans/2011

Verhoef, M. J., Boon, H., & Page, S. (2008). Talking to cancer patients about complementary therapies: Is it the physician’s responsibility? Current Oncology, 15(0), s88-s93.

Wang, C. (2011). Tai Chi and rheumatic diseases. Rheumatic Disease Clinics of North America, 37(1), 19-32.

Wang, C. (2012). Role of Tai Chi in the treatment of rheumatologic diseases. Current Rheumatology Reports, 14(6), 598-603.

More about A Close Look at Rheumatoid Arthritis

Open Document