Arrhythmogenic right ventricular dysplasia
Arrhythmogenic right ventricular dysplasia ( ARVD) is very rare and interesting strand of cardiomyopathy. ARVD occurs when the muscle tissue in the right ventricle perishes and is swapped by scar tissue. This process alters the electrical signals of the heart and causes arrhythmias. Symptoms include palpitations and fainting after extended periods of strenuous physical activity. ARVD generally affects teenagers or young adults.
Extrinsic
Extrinsic cardiomyopathy is a cardiomyopathy in which where the chief malformation is outside the myocardium itself . Most cardiomyopathies are indeed extrinsic. The most common causes of extrinsic cardiomyopathy are ischemia. Ischemia is basically poor oxygen supply of the heart muscle .
Intrinsic
Intrinsic cardiomyopathy is described as the weakness in the heart muscle that is not the result of external cause such as other diseases, obesity, and trauma. This definition is used to classify previously idiopathic cardiomyopathies although specific exterior causes have been acknowledged for many. For example , alcohol abuse has been identified as a cause for some forms of dilated cardiomyopathy. To make a diagnosis of an intrinsic cardiomyopathy , doctors should first eliminate the possibility of it being a coronary artery disease, which presents many similar signs and symptoms.
The intrinsic cardiomyopathies subclass has many different disease types, each with its own causes . Many intrinsic cardiomyopathies now have detectable external causes including drug and alcohol toxicity , certain infections, and other congenital factors. For example mutations in the cardiac desmosomal genes , as well as in the DES gene could cause arrhythmogenic right ventricu...
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Verapamil should not be used in patients with severe pulmonary hypertension because it may develop an extreme vasodilation, which worsens obstruction and cardiac output , and may result in pulmonary edema and can often be fatal if left untreated.
Another treatment is disopyramide . Disopyramide is used as an antiarrhythmic. And antiarrhythmic medicines have both antiarrhythmic and proarrhythmic properties, which mean you can adjust the patient's heart rate either making it faster or slower . Common side effects of disopyramide include dry mouth , urinary retention and blurred vision.
Pacemakers can be used to relieve symptoms of HCM , but have slowly been declining in popularity in the modern era due to their effectiveness being questioned. Development and research of the use of pacemakers ions show that there is no significant change in symptoms.
Epinephrine can be added to NE if needed to maintain acceptable BP, or substituted if necessary. Vasopressin (0.03 units/min) can be used as an adjunct to increase MAP,or to lower NE dose; it should not be used as a single agent. Dopamine can be used as an alternative to NE, but only in patients meeting criteria due to risk of arrhythmias; low dose dopamine not to be used for renal protection. Phenylephrine not recommended in most cases; can be utilized if NE leads to serious arrhythmias, CO is known to be high yet BP continues to be low, or as salvage therapy when MAP target is not achieved by other means. An arterial cath should be placed ASAP in patients who require vasopressors. Inotropes can be added to vasopressors or used alone, with a doubatmine trial of up to 20 mcg/kg/min as an option if myocardial dysfunction is suspected by elevated cardiac filling pressures and low CO, or if hypoperfusion is still evident although intravascular volume and MAP are at goal. Bicarbonate should not be used in patients with pH greater than or equal to
This is induced by the sliding of the cardiac myofibril. Hypertrophic Cardiomyopathy, also known as HCM, is a type of heart disease that affects the Cardiac Muscles and Cardiac Muscle cells. This disease occurs if the Cardiac Muscle cells enlarge, which causes the wall of the heart’s ventricles (most often the left ventricle) to thicken. It can also cause stiffness in the ventricles, as well as mitral valve and cellular changes. On a cellular level, HCM can cause the cells to become disorganised and lost.
It occurs because of repetitive electrical activity. This can occur in a patient with early or late heart failure, because there is damage to the heart tissue and the heart beats faster to try to supply the body with blood. Recommended treatment is elective cardioversion. Drugs used include an antidysrhythmic such as Mexitil or Sotalol (Ignatavicius &Workman, p. 728-729).
Cardiomyopathy, by definition, means the weakening of the heart muscle. The heart is operated by a striated muscle that relies on the autonomic nervous system to function. Cardiomyopathy is diagnosed in four different ways based on what caused the illness and exactly what part of the heart is weakened. The four main types of cardiomyopathy are dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular dysplasia. One other category of cardiomyopathy that is diagnosed is “unclassified cardiomyopathy.” Unclassified cardiomyopathy is the weakening of the heart that does not fit into the main four categories.
Emery-Dreifuss muscular dystrophy is a rare form of muscular dystrophy characterized by early onset contractures of the elbows, achilles tendons and post-cervical muscles with progressive muscle wasting and weakness It is also associated with heart complications like cardiomyopathy and arrhythmia which in both cases can lead to death. Cardiomyopathy is a heart disease which affects the muscles of the heart. In cardiomyopathy is muscles get rigid, enlarged or thick. They also sometimes changed by scar tissues. On the other hand arrhythmia is a disorder with the rhythm or rate of heartbeat. The heart can beat fast, which is called tachycardia or it could be beating too slow, which is called bradycardia. Emery-Dreifuss muscular dystrophy is characterized by early onset of contractures and humeroperoneal distribution. Humeroperoneal refers to effects on the humerus and fibula. The genes known to be responsible for EDMD encode proteins associated with the nuclear envelope: the emerin and the lamins A and C.
Cardiovascular disease is currently the leading cause of death in the United States. It is responsible for one in four deaths every year, about 600,000 mortalities. This disease affects men and women, as well as every ethnic group. Coronary artery disease is the most common cardiovascular disease, representing approximately 400,000 deaths per year of the aforementioned 600,000 total deaths from cardiovascular diseases as a whole. In 2010 alone, coronary artery disease cost the United States $108.9 billion for health care services, medication, and lost productivity. These chilling statistics, published every year by the American Medical Association, demonstrate the immediate need for new and innovative ways to prevent, detect, and treat coronary heart disease. This paper will explore the molecular biology behind the disease while explaining the current treatments and prevention that are available today, why they work and what can be done to improve them.
My patient who is a 57 year old male who has a past history of Hypertension, takes Accupril to help with his high blood pressure. Is complaining of chest and lest arm pain. He has a blood pressure of 140bpm a high heart rate, and on the ECG showing significant ST elevation and Sinus Tachycardia.
[11] Nishimura, Rick A., Ommen, Steve R., Tajik, A.J., (2003) Hypertrophic Cardiomyopathy: A Patient Perspective. Dallas, TX: American Heart Association,
“Heart failure is a chronic, progressive condition in which the heart muscle is unable to pump enough blood through to meet the body's needs for blood and oxygen” (American Heart Association, 2012, para 3). What this basically means is that the body is functioning in a way that the heart cannot keep up with. Although heart failure can be acute and occur suddenly, it usually develops over time and is a long-term or chronic condition. There are two different types of heart failure, left-sided and right-sided, and they can be caused by other diseases such as diabetes, coronary heart disease, or high blood pressure (National Institutes of Health, 2012). In most cases, both sides of the heart are affected simultaneously.
This condition can be treated various ways depending on “the type and frequency of arrhythmias, associated symptoms…, and the presence of structural heart disease” (Cleveland Clinic, 2014). Some patients may not need treatment at all, since they show not symptoms, since sometimes this condition can be naturally eliminated over the first year of life, but may still be required to have regular schedule appointments with the physician so the patients can be monitored. If symptoms are prevalent, the different treatment methods include a pacemaker, defibrillator, surgery, and medicine.
(Slide 5) Dilated cardiomyopathies results from a wide spectrum of genetic, inflammatory, toxic, and metabolic causes. However, at least 750,000 of the over 300 million U.S. population are likely to have idiopathic (ie: the cause is unknown) dilated cardiomyopathy (Hershberger). (Slide 6) Although many cases are currently classified as idiopathic, some examples of known causes include specific gene mutations, chronic excessive alcohol ingestion and other recreational drug use, chemotherapy, pregnancy, and viral myocarditis
Bradycardia can be very serious. Some of the symptoms are loss of consciousness, heart failure, or death. Slow heart rates are caused by heart block. The hearts natural pace-maker fails to be conducted to the ventricles, the hearts main pumping chambers.
...lso recommended not only for patients with dysrhythmias, but for everyone. It promotes a positive attitude, gets the blood flowing and is shown to reduce stress levels (Shea & Sears, 2008)
Cardiofaciocutaneous syndrome may be generated through various genetic mutations. As mentioned before, there are four genes that can cause this condition to be brought about in an individual. The most frequent mutation of these is the BRAF gene, because it is responsible for approximately 75 to 80 percent of each case of the syndrome. The two genes, MEK1 and MEK2, are very much alike and together are the result of 10 to 15 percent of ...
Genetics & Personalized Medicine. (2013). University of Ottawa Heart Institute. Retrieved on February 3, 2014 from: http://www.ottawaheart.ca/research_discovery/genetics-personalized-medicine.htm