covalently bonded to at least two or non-metal ions in the same molecule. They are classified based on their covalently bonding and stability resistance to biological transformants, high affinity, level of removal of metal during detoxification. Chelation therapy is a well-studied therapy by known to remove condensate which are transition metals (Ca, Mn, Pb, Ar) that are accumulated in the blood stream. Chelating agents are restricted only to the surface of the blood stream they do not penetrate the
Thalassemia is an inherited blood disorder characterized by low amounts of hemoglobin and a low count of erythrocytes in the body. Thalassemia is caused by mutations in the deoxyribonucleic acid of cells, which makes hemoglobin. The mutations are passed from parent to child. The mutations vary depending on the type of Thalassemia inherited. The variation in the mutation occurs from the number of gene mutations, which are inherited, as well as mutation within the hemoglobin molecule. Clinical
Heavy Metal Poisoning Heavy metal poisoning is the toxic accumulation of heavy metals in the soft tissues of the body. Heavy metals are chemical elements that have a specific gravity at least five times that of water. The heavy metals most often implicated in human poisoning are lead, mercury, arsenic, and cadmium. Some heavy metals, such as zinc, copper, chromium, iron, and manganese, are required by the body in small amounts, but these same elements can be toxic in larger quantities. Heavy metals
approved by the United States Food and Drug Administration, yet about 111,000 adults in the United States used chelation therapy as a form of complementary medicine in the year of 2007. [Chelation for Coronary Heart Disease. (2016). Retrieved November 28, 2016, from https://nccih.nih.gov/health/chelation]. Dr. Rekha Mankad, M.D. argues that some doctors are concerned about the safety of chelation therapy as treatment because the safety and effectiveness cannot be determined. She also goes on to write
electrostatic repulsion and chelation [14, 31]. The formation of ternary complexes is the mechanism for the adsorption of alkaline and alkaline-earth ions[29], and the electrostatic repulsion occurs in systems concerning chitosan and anions[29], therefore those mechanism
Lead Toxicity in Children Lead poisoning in children was first discovered in 1890 in Queensland, Australia. The lead source was not identified until 1904, when a researcher traced it to the paint used on railings and verandahs. The first discovery of lead poisoning in the United States (with a traceable source) was in 1914; the child had chewed the paint off of his crib. At this time they linked lead poisoning as a cause of convulsions in children. As research progressed and more children were
Based on the research that has been conducted by Gupta (2005), Bhapkar et. al (2013), Subissi et. al (2010), and ciclopirox is available in 8% nail lacquer topical solution. Ciclopirox nail lacquer is a clear, colourless pale to yellow solution that is used to treat the infection on the fingernails and toenails and this each gram ciclopirox nail lacquer do contain 80 mg of ciclopirox (Gupta, 2005). For these ciclopirox derivatives, ciclopirox is an active ingredient to treat the onychomycosis safely
ASSIGNMENT: THE CRIMES OF LEAD 1.What are the primary sources of environmental and occupational exposures to lead? Ans) Primary sources: a. Burning fossil fuels b. Mining c. Manufacturing Other sources: d. Lead paint in older houses e. Contaminated soil f. Household dust g. Drinking water h. Lead glazed plates and cups a. Painting, Plumbing and Welding b. Automotive repair c. Ammunition manufacturing d. Production of batteries and gasoline 2. List and briefly explain the common and most important
Once used for varying applications, lead is now known for its toxicity in the human body. Dr. Gary Goldstein, the chief executive of Kennedy Krieger Institute wrote, “Exposure to excessive amounts of inorganic lead during toddler years may produce lasting adverse effects upon brain function (Goldstein 1990).” Lead poisoning awareness has become increasingly prevalent in the American government, with lead poisoning testing recommended as early as nine to twelve months of age (Health and Human Services
Polluted air in general contains one or more hazardous substances that create hazards for the health of living individuals. Pollutants within the air are measured in terms of particulate matter (PM); or the number of particles of potentially hazardous substances as a percentage of air. Outdoor air pollutants can create acid rain, which affects the environment and depletion of the ozone layer by chlorofluorocarbons (CFC's), which increases the risk of skin cancer and cataracts in human individuals
contamination you were exposed to, and have the authorities remove the contamination. The doctors will admit the patient to ICU, and closely monitor them. If tested positive some people use a therapy called chelation, which is used to treat toxic metals inside the body (http://nccam.nih.gov/health/chelation). More severe cases a filtration of the blood are used. Less severe cases by using ultra violet light on aquatic environment it can break down the mercury or methyl mercury into a gas form. FDA warns
History of sickle cell Many people can prove to the fact that sickle cell originated in Africa. Going by different names related to tribal languages but in 1910 a young dental student came to the office of Doctor James B. Herrick, a cardiologists complaining of black problems Herrick wanted nothing to do with young kids. So he referred him to Dr.Ernest Irons after drawing flood and examines it. Dr.Irons notice that the red blood cells had a sickle shape at that moment he immediately informed Dr
TOPIC OUTLINE Thesis: The use of alternative medicine in autistic kids should include medical supervision in order to avoid overdosing, internal bleeding, and organ failure. I. Risks associated with alternative medicines II. Autistic kids Characteristics III. Medication without medical supervision SENTENCE OUTLINE Thesis: The use of alternative medicine in autistic kids should include medical supervision in order to avoid overdosing, internal bleeding, and organ failure. I. The
COORDINATION COMPOUNDS: Coordination compounds are those which are electrically neutral and contain complex ions. Complex ions are those compounds in which central metal atom is bonded to ligand by coordinate covalent bond. The complex can be charged so coordination compound is balanced by counter ion. Coordinate covalent bond is the bond in which electron pair is donated by one bonded atom only. The atoms which donate and accept the pair of electron are called donor and acceptor respectively. Ligand
General Information about Urease Urease is an enzyme found abundantly within organisms such as plants, fungi, bacteria, invertebrates, and is also present within the soil. Its function is to convert the organic compound urea into ammonia and carbon dioxide. Within animals, urea is excreted as a waste compound through the metabolism of nitrogen-containing substances; urease is therefore not required within animals. For organisms such as plants, fungi, bacteria etc., urea serves as a source of nitrogen
Lipids are a major source of energy and provide essential lipid nutrients. In many food products the lipid component plays a major role in determining the overall characteristics, such, as flavour, texture, mouthfeel and appearance (Ross & Smith, 2006). However, fats, oils and lipid-based products deteriorate during heat processing, distribution and long term storage. The chemical deterioration is as a result of lipid oxidation. In some chesses, a limited amount of lipid oxidation is desirable for
Thalassemia is a blood disorder transferred through families. It occurs when the body makes less hemoglobin than needed or an unusual form of hemoglobin. Hemoglobin is the protein in red blood cells that carry oxygen. The disorder makes an excessive amount of destruction of red blood cells. This eventually leads to anemia. There are two main types of thalassemia. The first one is Alpha thalassemia. This occurs when a gene or genes related to the alpha globin protein are missing or mutated. It happens
Topic: Thalassemia disorder Thalassemia is an inherited co-dominant blood disease. It is characterized by reduced synthesis of the hemoglobin and less red blood in children affected by this disorder. Hemoglobin is the means through which red blood cells carry oxygen in our body. We need two forms of globin genes to make beta globin chains in our body, one from each globin gene. If one or two of these genes are defective, it produces beta thalassemia which is the less severe form of this disease
Cell death restrains the superfluity of physiological processes such as embryogenesis, post-embryonic development (Penaloza et al, 2006) and tissue homeostasis and abrogating cell death provokes various diseases such as autoimmune diseases and cancers. (Galluzzi, Maiuri et al. 2007) In the long time of cell death related studies researcher have found dozens of methods to study the death related parameters but none of these method fulfill the requirement. NCCD (Nomenclature Committee on Cell Death)
Although the early-onset AD related to specific genetic mutations seem to have a stronger relationship to the AβH, it only accounts for less then 5% of the cases (Knopman, 2014). The other cases, classified as late-onset AD, have not be fully understood only with the advent of the AβH, although both types of AD bear plaques and tangles, hallmarks of the disease. I. What is the real role of Aβ? One of the most refutable arguments against the amyloid-beta theory is that a considerate amount of elders