Lupus (systemic lupus erythematosus) is an autoimmune condition that is characterized by systematic damages caused on the immune system by the body itself. The most affected parts if the body by this condition are, heart, kidney, liver, joints, and the brain. With these parts of the body affected, the entire body can end up being paralyzed or rather not working well. Lupus or SLE is commonly recognized by butterfly rush which spreads across the nose and cheeks (Magro et al. 2013). However, the most common symptoms for lupus are joint pains and swellings, kidney failures, fatigue, and photosensitivity.
Lupus is mainly caused by a combination of genetic predisposition and environmental triggers. According to Magro et al., genes, environment, and genetic factors cause lupus (2013). The most affected by this condition are women compared to men. In addition, lupus affects people aged between 20- 40, although, children are said to rarely get lupus. Initially, a person diagnosed with lupus was said to die because there was no treatment. However, with the advancement in treatment and prevention methods, people with lupus can live normal lives. With proper treatment of lupus, the condition can be managed and the affected organs protected from severe damages.
Just like lupus, Multiple sclerosis is a chronic immune system disease that affects the central nervous system. The cause of this condition is unknown; however, some of the causes are violent trauma to the head or spinal cord, and or an immune system attack, which causes the body to attack the myelin sheaths around the neurons in the ascending and descending pathways and most of all genetic and environmental factors. Rosner (2008) notes that, multiple sclerosis is the common cause ...
... middle of paper ...
...er similarity id that they have no cure, mainly affects women, only symptoms are treatable and they start in early adulthood. Conversely, as much as they are both autoimmune conditions, lupus attacks skin, joints, and the nervous system while multiple sclerosis deteriorates the protective sheaths around the nerve cells, which later on results to the damage of the nervous system and the brain.
Works Cited
Ferreira, S. D'Cruz, D. P. and Hughes, G. R. V. (2005). Multiple sclerosis, neuropsychiatric lupus and antiphospholipid syndrome: where do we stand? Rheumatology, 44 (4): 434-442.
Rosner, J. (2008). Multiple Sclerosis. New York, Simon & Schuster.
Magro, C., Cohen, D., Bollen, E. L., Buchem M. A., Huizinga, T.W., and Steup-Beekman, G. M. (2013). Demyelinating disease in SLE: is it multiple sclerosis or lupus? Best Practice Res Clinic Rheumatol. 27(3):405-24
Multiple sclerosis (MS) is a disease affecting the myelination of the central nervous system, leading to numerous issues regarding muscle strength, coordination, balance, sensation, vision, and even some cognitive defects. Unfortunately, the etiology of MS is not known, however, it is generally thought of and accepted as being an autoimmune disorder inside of the central nervous system (Rietberg, et al. 2004). According to a study (Noonan, et al. 2010) on the prevalence of MS, the disease affects more than 1 million people across the world, and approximately 85% of those that are affected will suffer from unpredictably occurring sessions of exacerbations and remissions. The report (Noonan, et al. 2010) found that the prevalence of MS was much higher in women than in men, and that it was also higher in non-Hispanic whites than in other racial or ethnic groups throughout the 3 regions of the United States that were studied.
The incidence of SLE is 7.6 cases per 100,000 with a prevalence of approximately 68 cases per 100,000 (Bernknopf, Rowley, & Bailey, 2011). It affects women more than men with a 9:1 ratio, and typically affects women of childbearing age (Patel, Fenves, & Colbert, 2012). The mean age of symptom onset was 29 years in the Euro Lupus Project that studied 1000 patients with SLE (“Systemic Lupus Erythematosus”, 2012). Children and older adults are also diagnosed with SLE but at a much lower rate, 8%-15% and 3%-18%, respectively (Arnaud, Mathian, Boddaert, & Amoura, 2010). Patients with ethnic backgrounds have a higher incidence rate with African Americans developing SLE 3-4 times more than Caucasians, unlike drug-induced lupus erythematosus (DILE) which has an equal male to female prevalence yet a higher disease severity in Caucasians (Bernknopf, Rowley, & Bailey, 2011).
Around the world, many people are living with neurologically debilitating disorders like multiple sclerosis. Multiple sclerosis is best described as a pathological “inflammatory-mediated demyelinating disease of the human central nervous system,” and affects more than 2.5 million people globally (Trapp & Nave, 2008).
Well what causes MS? When you have damaged nerve signals that is one way you can get it. Another way is you is it could be genetic or environmental. The other way you can cause it is by infections. Woman would be more common to get MS than a man. The ages
Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks healthy tissue and organs. This inflammation can damage many different bodily systems. Lupus commonly affects the joints, skin, kidneys, lungs, brain and heart. Many people with lupus have found relief for some of their chronic pain through practicing a few different styles of yoga.
When someone has lupus they have a different outlook on life. For patients with this disease, even the easiest task can be painful to the body or joints. Lupus is not contagious. “Lupus is a disease of the immune system. The immune system protects the body from inflection”(http://lupus.webmd.com). With lupus, the immune system attacks the tissue in many parts of the body. Lupus affects women more than men(www.womenshealth.gov). There are many different types of lupus, and each symptom affect different parts of the body. With treatment you can obtain and fulfill a healthy lifestyle.
Point #1: “Lupus is a chronic (6 wks. -Years), autoimmune disease that occurs when your body’s immune system damages any part of your body such as the skin, joints, and organs.”
According to National Multiple Sclerosis Society, Multiple Sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system (CNS) that disrupts the flow of information within the brain, and between the brain and body. The central nervous system (CNS) comprises of the brain and the spinal cord. CNS is coated and protected by myelin sheath that is made of fatty tissues (Slomski, 2005). The inflammation and damage of the myelin sheath causing it to form a scar (sclerosis). This results in a number of physical and mental symptoms, including weakness, loss of coordination, and loss of speech and vision. The way the disease affect people is always different; some people experience only a single attack and recover quickly, while others condition degenerate over time (Wexler, 2013). Hence, the diagnosis of MS is mostly done by eliminating the symptoms of other diseases. Multiple sclerosis (MS) affects both men and women, but generally, it is more common in women more than men. The disease is most usually diagnosed between ages 20 and 40, however, it can occur at any age. Someone with a family history of the disease is more likely to suffer from it. Although MS is not
Lupus is a dangerous disease that can affect anyone. It has no cure and is known to affect 9 out of 10 adults. “Systemic lupus erythematosus (SLE), also called lupus, is a chronic inflammatory autoimmune disease characterized by unusual antibodies in the blood that target tissues of the body.” (Frazier & Drzymkowski, 2008) Autoimmune means that your immune system cannot tell the difference between foreign invaders and your body’s healthy tissues and creates autoantibodies that attack and destroy healthy tissue. These autoantibodies cause inflammation, pain, and damage in various parts of the body. Lupus affects each individual differently and it may be worse for one person than it is for another. My grandmother, Carolyn, was diagnosed with Systemic lupus erythematosus in her early forties. She suffered a long time before she was diagnosed with Lupus. “The worst part of my lupus is the flare-ups” Carolyn said, “It feels as if I am on fire sometimes and every single inch of my body hurts in the most awful way I have ev...
Multiple Sclerosis (MS) is a complicated chronic deteriorating disease that has an effect on the central nervous system (CNS). This disease causes destruction of the myelin around the nerve fibers. “The exact etiology of Multiple Sclerosis is unknown; however, it is thought to be an immune mediated disease. MS is characterized by CNS inflammation, demyelination, and axonal loss” (Compston & Coles, 2008). Typically, it is described by early relapses and remissions of neurological signs of the CNS. This is known as relapsing-remitting MS (RRMS). MS can be identified by a variety of known risk factors. Multiple Sclerosis can be brought on by a mixture of inherited and environmental risk factors such as smoking or an exposure to a virus like Epstein Barr. The inflammatory process has an interesting role on the central nervous system.
Primarily, the term MS refers to a chronic disorder that attacks the central nervous system (CNS). It is most common in temperate continents such as Europe and Australia with Asiatic and African continents having a lower risk of the disease (Wiley Online Library, 2013). A search organised by the Multiple Sclerosis Society (2013) has estimated that there are 127,000 people living with MS in the United Kingdom. Further research by Chipps, Clanin, and Campbell (1992, pp. 158-167) shows that MS disorder more likely affects women than men with its symptoms occurring between the ages of 20 and 40 in most cases and is quite uncommon in childhood and old age. The nerve cells known as neurons in the brain constantly transmit and receive signals. They invoke emotions, activities and cognition that constitute the day to day experiences of humans. Under normal circumstances, these signals travel on a protected insulation path known as the myelin sheath. This insulation is vital as it enables signals to reach their target. In Multiple Sclerosis, the myelin sheath gets disintegrated causing the nerve fibre to be damaged leading to a disruption in the abili...
The etiology of the disease is not yet known. There is a discussion that there is action of one or more exogen factors, which after a long latent period trigger the disease in genetically receptive people. MS is characterized by a geographical and demographical spread, with frequency going up when moving away from the equator and again going down in the polar regions. Approximatly 30/100000 people have the disease globally.
... resulting impairment to the CNS. The first group of mice exhibited a pattern of CNS inflammation that resembled that of the most common subtype of MS, RRMS, with lesions filled with macrophages, a type of immune defender cell. The second group of mice displayed inflammation deep in the CNS tissues and in the optic nerve with lesions filled with neutrophils, another type of immune cell. Both groups of mice were given antibody drugs similar to drugs being developed against MS in humans. The effects were observed over time and results showed that some of the drugs inhibited disease in the first group of mice but did not inhibit disease in the second group. Thus, as Mark Kroenke (2008), the study’s first author and a Ph.D. student in immunology at U-M stated, "That's our proof that these really are different mechanisms of disease" (Kroenke et al., 2008).
In nearly 85% of patients with untreated SLE test positive of dsDNA. This finding shows that it is probable SLE even though it is not always present in every case, but because it is not seen positive with other connective tissue problems, it is associated with Lupus.
Multiple Sclerosis (MS) is an erratic disease of the central nervous system that is often disabling. This disease interrupts the transmission of information from the brain to the body. MS attacks the myelin on nerve cells, which is a coating around the cells. The cause of MS is still unknown. Researchers believe that people are born with a genetic predisposition and that can be triggered by unknown environmental factors which result in developing the disease. MS affects 2.3 million people in the world. Though, the cause is unknown, there are factors that are associated with the disease including gender, genetics, age, geography, and ethnic background. The majority of people with MS are diagnosed between the ages of 20 and 50. MS is