Hypothermia Therapy for Treatment of Patients with Potential Ischemia

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Therapeutic hypothermia
The use of Therapeutic hypothermia for treatment of patients with potential ischemia has been around for around for about 70 years. After fading into and out of popularity for the past half century, therapeutic hypothermia has reemerged as a state of the art lifesaving tool in the fight of a potentially hypoxic brain injury. Even though the evidence to the support this treatment is growing, more research is needed to decide if this treatment will become the new standard of care for these patients, or if it will fall by the wayside. In the past 25 years EMS has gone under drastic changes in the way that we treat patients, with cutting edge emergency medicine and state of the art equipment and with months of detailed and in depth training, todays paramedic is well equipped to handle every medical emergency they can encounter. But, even though all of these advances have been made, the chance of a patient making a full recovery following an out-of-hospital cardiac arrest is extremely low.
It is generally known that the brain does not respond well to that of hypoxic events, most all situations the golden 5-7 minutes ‘point of no return rule’ still is acknowledged, but a large part of the problem is that fact that brain damage will continue to occur for several hours following resuscitation, just because the heart begins beating again does not mean that ischemia has stopped. One study shows that while 17 -25% of cardiac arrest patients survived to hospital admission, only 4-9% (Bernard) left the hospital neurologically intact. Some research has shown, however, that therapeutic hypothermia can help increase the odds of these patients regaining 100% of neurological function by the time that they leave the hospital...

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... immune system response, hypoglycemia, hyperkalemia, a generally lower cardiac index, a high risk of hospital acquired pneumonia secondary to the decrease immune system response, impaired clotting factors, and shivering from the patients that could negate the therapy itself
The EMS role in therapeutic hypothermia is that of much importance, who is the first one on scene with these patients? Nine times out of ten EMS is by the patient’s side within minutes and who better to start this therapy than those of paramedics. The use of hypothermic fluids usually must continue for a minimum of 12 hours following a sudden cardiac arrest. And seeing as how the potent effects of therapeutic hypothermia can be decreased by withholding the treatment even a matter of minutes, EMS is by far in the best position to begin the treatment in the field, before arriving at the hospital.

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