Maple Syrup Urine Disease
An Amish family was concerned about a newborn boy that began to eat poorly 5 days after birth and was not gaining weight. The infant made repetitious gestures resembling the movements of fencing or bicycling. The baby’s urine has a characteristic maple syrup odor. The family had three other infants, all of whom died of an undiagnosed metabolic disorder within three months of birth. All three infants had urine that smelled distinctly of burned sugar. The baby’s diagnosis is maple syrup disorder,
Maple syrup urine disease is an inherited disorder. This disease is usually found in newborns twenty four hours after they are born. Symptoms include lethargy which is lack of energy, seizures, vomiting, coma, loss of appetite, fussiness, mental and physical retardation, hypotonia when the muscles stiffen, weight loss, and urine that smells like maple syrup. Even though this disease is usually found in newborn babies, it can also occur in later infancy or childhood. When a baby is born they run a test on a sample of blood to see if the baby has MSUD. There can be three types of MSUD. The most common type is Classic MSUD the baby starts to develop some symptoms 4-7 days after they are born. Intermediate MSUD can be found in older babies, 10 months or older the symptoms are growth and mental development delay. Intermittent MSUD in this type the babies usually show no symptoms until they are older. The patients can have episodic ataxia which is when they lose control of their body movements, and lack of energy. Although they are very similar the severity is not as well as the treatment.
This disease is mainly caused by the mutation of a gene which causes a mutation in the BCKD (branched-chain alpha-ketoacid dehy...
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Vital to maintenance of homeostasis is the regulation of plasma osmolality. The Renin-Angiotensin-Aldosterone system, which works to regulate blood pressure, plays a crucial role in fluid balance. When dehydration occurs, blood osmolality increases, which stimulates the release of antidiuretic hormone (ADH), ultimately leading to increased water reabsorption. This leads to more concentrated urine, and less concentrated plasma. Low plasma osmolality works in the opposite fashion: ADH release is inhibited, water reabsorption decreases, and urine is less concentrated. The added electrolytes and carbohydrates in Gatorade would facilitate greater fluid retention through stimulation of renin and vasopressin, increasing urinary sodium reabsorption (3). Studies of both urine volume and plasma volume changes are eff...
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Canada exports approximately 2500-3000 tonnes of maple syrup to Japan annually. Since this makes Canada Japan’s largest source of maple syrup, our principal competitors are the existing Canadian companies that create and export maple syrup to Japan. Some of these competitors are L.B. Maple Treat, H.T. Emicott, and Maple Terroir. L.B. Maple Treat has been in the maple syrup industry for over 35 years. They use no chemicals, preservatives, or additives in the production of their maple syrup. They participated in a Japanese international...
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“Honey and maple syrup,” Mary said. “We’re still pretty well stocked from last year, but it’ll be nice to get production ramped back up now that spring has sprung,
Not only maple trees have been tapped for syrup. The Birch and Elm trees have been used for syrup, but the maples produce a much sweeter sap than any other tree. "What is more peculiar is that the sap, unlike nectar, does not come from the leaves (they
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According to Krisha McCoy on her article: The history of Diabetes; “In 150 AD, the Greek physician Arateus described what we now call diabetes as "the melting down of flesh and limbs into urine." From then on, physicians began to gain a better understanding about diabetes. Centuries later, people known as "water tasters" diagnosed diabetes by tasting the urine of people suspected to have it. If urine tasted sweet, diabetes was diagnosed. To acknowledge this feature, in 1675 the word "mellitus," meaning honey, was added to the name "diabetes," meaning siphon. It wasn't until the 1800s that scientists developed chemical tests to detect the presence of sugar in the urine”.