The Use of Proton Pump Inhibitors

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Research is showing that the numbers of proton pump inhibitors (PPIs) are being over prescribed during hospital stays and subsequently on discharge. There are studies published that show there are opportunities for substantial cost savings in relation to PPI prescription if there were some clinical guidelines used across the board nationwide. In addition to the costs, there are also risks for devastating side effects of continued use. There is a need to have a more defined reason for the administration and continuation of PPI’s. The need for proton pump inhibitors Being admitted to a hospital is a scary thing – especially when unexpected. There is a common trend seen among patients when they are admitted. They are usually less mobile, taking multiple medications and prone to stress ulcers from the hospital stay itself. All of the aforementioned reasons can cause stress ulcers. This means there is a reflux of stomach contents into the lower esophagus. Excess stomach acid occurs when the patient is immobile due to the gastric contents moving from a lower pressure to a higher pressure. (Lewis, 2007 p.1003) Typically, this occurs when the patient is in a supine position or with an increase in abdominal pressure. There are a variety of reasons why the decreased pressure in the lower esophageal sphincter - ranging from medications to diet. Doctors know this is a common manifestation and for that reason they will prescribe a proton pump inhibitor or PPI when the patient is admitted. PPI’s work by decreasing the amount of acid produced in the stomach. Some examples of these medications are omeprazole, lansoprazole, and pantoprazole. These medications are used to treat erosive esophagitis, which is damage to the esophagus from stomach... ... middle of paper ... ...cking a PPI: It comes down to cost. Journal Of Family Practice, 57(4), 231-236. Cahir, C., Fahey, T., Tilson, L., Teljeur, C., & Bennett, K. (2012). Proton pump inhibitors: potential cost reductions by applying prescribing guidelines. BMC Health Services Research, 12(1), 408-415. doi:10.1186/1472-6963-12-408 Hughes, J. D., Tanpurekul, W., Keen, N. C., & Ee, H. C. (2009). Reducing the cost of proton pump inhibitors by adopting best practice. Quality In Primary Care, 17(1), 15-21. Bernard, L., Fendrick, A., Inadomi, J., & McIntyre, L. (2013) Center for Biotechnology Step-down from multiple- to single-dose proton pump inhibitors (PPIs): a prospective study of patients with heartburn or acid regurgitation completely relieved with PPIs. Am J Gastroentero Coggins, M. O. (2014). RECOGNIZING PROTON PUMP INHIBITOR RISK. Today's Geriatric Medicine, 7(1), 6-8.

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