Pregnancy and Bipolar Disorder

763 Words2 Pages

Many females suffer from depression and for most they may not know what to do in the case of pregnancy. I for one wouldn’t know what the best route of action would be. Is it safer to continue mood stabling treatments or discontinue them during pregnancy? This study assessed the danger of return of mood occurrences among women with a history of bipolar disorder that continued or stopped treatment with mood stabilizers during pregnancy. In a prospective observational clinical cohort study, the authors determined recurrence risk and survival-analysis-based time to recurrence of a new episode in 89 pregnant women with bipolar disorder. Eligible subjects were euthymic at conception and continued mood stabilizer treatment or discontinued treatment proximate to conception. The overall risk of at least one relapse was 71%. The females who discontinued treatment verse continued with their mood stabilizer treatment the recurrence risk where two times greater. The average time to first recurrence was more than four times shorter, and the number of weeks ill during pregnancy was five times greater. The average recurrence of inactivity was eleven times shorter after immediate and quick discontinuation versus steady discontinuation of mood stabilizer. Most recurrences were depressive or varied at 74% with 47% occurred during the first trimester. The factors of relapse involved bipolar II bipolar diagnosis, earlier onset, and extra recurrences per year, current sickness, usage of antidepressants, and usage of anticonvulsants versus lithium. In conclusion discontinuation of a mood stabilizer especially when stopped abruptly during pregnancy carries a higher risk for more illnesses in females with bipolar disorder, especially for premature depres... ... middle of paper ... ...ndling the discontinuation or even continuation of medications should be done in a proper manner to alleviate any relapse. Works Cited Gülöksüz, S., Akdeniz, F., Ince, B., & Oral, E. T. (2010). The treatment of bipolar disorder during pregnancy and the postpartum period. Turk Psikiyatri Dergisi, 21(2), 1-66. Retrieved from http://search.proquest.com/docview/744031121?accountid=158307] Yonkers, K. A., Wisner, K. L., Stowe, Z., Leibenluft, E., & al, e. (2004). Management of bipolar disorder during pregnancy and the postpartum period. The American Journal of Psychiatry, 161(4), 608-20. Retrieved from http://search.proquest.com/docview/220491083?accountid=158307 Freeman, M. P., M.D. (2007). Bipolar disorder and pregnancy: Risks revealed. The American Journal of Psychiatry, 164(12), 1771-3. Retrieved from http://search.proquest.com/docview/220483539?accountid=158307

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