Gain of Function or Gain or Risk? In the world of viral research today, the study of Enhanced Pathogens is a risky, if not dangerous, field of research.The big question regarding research on enhanced pathogens stands with: is deeper knowledge about the pathogen worth the risk of accidentally spreading them, or is it too hazardous? Well, Enhanced Pathogens are dangerous, but they aren't as dangerous and complicated as they seem to be. In fact, they are the least harmful in a few cases, but still can cause some troubles along the way. Enhanced Pathogens are used to provide vital insights while treating the viruses. Although, when they are used to increase mammalian transmissibility and virulence, the altered viruses pose serious Biosafety risks. Even though it can insure preparedness for the public in case of an outbreak of any such pandemic diseases, like in case of Ebola, MERS, SARS., Enhanced Pathogens is a huge Biosafety risk to society today because Influenza virus, which is a pathogen, is one of a handful of infectious disease agents that can cause devastating pandemics with high mortality and morbidity in human populations that can kill thousands of people each year. With that being said, in November of 2014, I agree with The White House suspending the research that could possibly enhance …show more content…
It would be great to have a vaccination to cure most of our viruses and diseases we have now. Not only could this help cure our problems, but it could help keep birds and other types of animals from spreading things like the bird flu, and it could help us find out what makes them immune to some viruses that we get today. It could provide us with the vaccines that we're not immune to this day. This study could provide huge advances in today's world, but would you really risk the lives you love and care about to test out these conclusions that could possibly go wrong in so many
Heloisa Sabin helped establish the Sabin Vaccine Institute in 1993 whose mission is to promote the role of vaccines which will eliminate needless deaths from preventable and treatable diseases. (Heloisa Sabin | Sabin Vaccine Institute). Her essay is an extension of her husband’s work and views. ““There could have been no oral polio vaccine without the use of innumerable animals, a very large number of animals,” Albert told a reporter shortly before his death” (Sabin 155). Through citing her husband’s views to support her argument she empowers her essay with the credibility of a man who is responsible for curing a disease that “struck down 58,000 children in 1952 alone” (Sabin 154). To take away the ability to test on animals would be the same as condemning those children to pain, suffering and death. As for Jane Goodall, she has no formal education or training (Muller 157). Jane’s life experience come from following a childhood dream of living with animals and doing a much...
However due to globalization, import and export viruses is more easily transmitted. Over the past century the global community especially Asian has been affected with new strains of the influenza virus. The changes in the virus can occur in two ways “antigenic drift” which are gradual changes in the virus over time. This change produces new strains that the antibody may not recognize. “Antigenic shift” On the other is a sudden change in the influenza virus which ‘’ results in a new influenza A subtype or a virus with a hemagglutinin or a hemagglutinin and neuraminidase combination that has emerged from an animal population,” as seen with H5N1 virus. This change leaves people defenseless against this new virus. (CDC, 2013) Currently there is no vaccine to combat all strains therefore “Planning and preparedness for implementing mitigation strategies during a pandemic requires participation by all levels o...
One of the most virulent strains of influenza in history ravaged the world and decimated the populations around the world. Present during World War I, the 1918 strain of pandemic influenza found many opportunities to spread through the war. At the time, science wasn’t advanced enough to study the virus, much less find a cure; medical personnel were helpless when it came to fighting the disease, and so the flu went on to infect millions and kill at a rate 25 times higher than the standard.
What would the world be like if there was no vaccine for polio? If there was no discovery of insulin? Thanks to animal research we don’t have to live without vaccines or insulin. Animal research is a topic debated everyday around the world. Some argue it is cruel to put animals through experiments that animals have no voice in what is being done to them. Others argue that animal testing is good because it collects a lot of information and helps with surgical techniques. I believe that without animal testing we would never know what we know now. Animal testing for medical research is necessary if there are no other alternatives because it allows for advances in medicine, provides treatments for people with diseases, it eliminates human suffering, and it also has helped treat diseases in animals. (Animal Research 2013)
middle of paper ... ... This idea needs to be remembered by scientists who just want a little more freedom. The United States is the freest country in the world, and in order for it to stay that way, it needs to stay protected with censorship and the use of caution. References Begelman, D. A. & Co., Inc.
Over the past fifteen years H5N1 influenza (also known as Avian Flu or Bird Flu) has become a common topic of speculation and debate worldwide, causing quite a bit of confusion about its possible impacts on our society. At this point in time it is generally recognized by the international medical community that Avian Flu is bound to become a pandemic, most likely within the next ten years. Research on Avian Flu and its effects have led many scholars to make grave predictions of major global turmoil while a small portion of medical scientists remain skeptical, believing we will have enough time to thoroughly prepare for the outbreak. The one thing that nearly all health professionals seem to agree upon is that the avian flu will surely have a large impact on the development of humankind. To truly understand the threat of this disease and what we must do to prepare for it, we need to look at the issue from multiple angles and consider what the spread of a disease so lethal and so prone to mutation would mean for our daily lives, health professionals, laws and government procedures, and of course the continuation of the human race.
...in the fields of both science and medicine, future epidemics of any disease can be handled better. When a lethal disease begins to rampage a population, research on similar epidemics can help the world contain, cure, and prevent the disease to protect the world and its population.
Influenza is a major public health problem which outbreaks all over the world. Resulting in considerable sickness and death rates. Furthermore, it is a highly infectious airborne disease and is caused by the influenza virus. Influenza is transmitted easily from one person to another person which has a great impact on society. When a member of society becomes sick, it is more prone to spread to other people. In the United States, every year between 5 to 20 percent of the population is affected by influenza. As a result of this, between 3,000 and 49,000 deaths have occurred per year (Biggerstaff et al., 2014). Therefore, the influenza vaccine is the most effective strategy to prevent influenza. This essay will examine two significant reasons for influenza vaccination which are the loss of workforce and economic burden as well as one effect regarding herd immunity.
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi or parasite who live both inside and outside our bodies and are normally helpful but can cause infectious diseases to the human (body) system under certain conditions. And for a disease to be infectious, there is what is called ‘’chain of infection’’ that takes place before. And this can be seen in the below diagram:
At no time was a search for the cure for influenza more frantic than after the devastating effects of the pandemic of 1918. The pandemic killed somewhere between twenty and a hundred million people, making it twenty five times more deadly than the ordinary cough and sneeze flu. The symptoms of this flu were like something straight out of a horror movie: the victim’s facial complexion changed to a dark, brownish purple, the feet turned black, and they began to cough up blood. Eventually, death was caused, literally by drowning, when the victim’s lungs filled with their own blood. The first scientist to claim to solve the enigma of influenza was Dr. Friedrich Johann Pfeiffer. He isolated a bacterium he named Hemophilus influenzae from the respiratory tract of those who had the flu in the pandemic of 1890. He was believed to be correct in his discovery until the pandemic of 1918, when scientists searched the respiratory tracts of influenza victims and only sometimes found his bacterium. Robert E. Shope and his mentor Paul Lewis were the next to attempt to crack the code of influenza. They chose to study the disease in pigs, a controversial choice because many people believed that the swine influenza pigs were contracting was not the same as the human flu. The first experiment they ran was ba...
Believe it or not, but investing money in vaccines actually helps our economy. When a person thinks about it, it makes sense. For every vaccine you receive, the less likely you will have to pay medical expenses if you get sick. And that money adds up, “Every $1 invested in immunization returns an estimated $16 in health-care savings and increased economic productivity” (Bustreo par. 4). Using those statistics, every ten dollars a person spends on getting a flu vaccine potentially saves them one hundred-sixty dollars from doctor visits. Imagine what that could do in third world countries where hundreds of people are dying everyday from vaccine-preventable diseases. Imagine how quickly that money could add up. Not only would it save their citizens’ lives, it would actually help their economy
...mptoms and known pattern of disease. Experiments by scientists, Nicolle and Le Bailly in Paris, were the earliest explanations that influenza was caused by a filter-passing virus. They proved that influenza was due to a submicroscopic infectious agent and not a bacteria. Scientific experiments, such as these, had immediate preventative applications. They were part of an effort to create a vaccine that would prevent the influenza. Vaccines were considered the best preventative treatment at the time. Several scientists tried to create effective vaccines, each with a different understanding of the virus. Dr. Rosenow invented a vaccine to target the multiple bacterial agents involved from the serum of patients. He aimed to raise the immunity against the bacteria, and not the cause of the initial symptoms (Virginia).
A few years before 1918, in the height of the First World War, a calamity occurred that stripped the globe of at least 50 million lives. (Taubenberger, 1918) This calamity was not the death toll of the war; albeit, some individuals may argue the globalization associated with the First World War perpetuated the persistence of this calamity. This calamity was referred to the Spanish Flu of 1918, but calling this devastating pestilence the “Spanish Flu” may be a historical inaccuracy, as research and historians suggest that the likelihood of this disease originating in Spain seams greatly improbable. Despite it’s misnomer, the Spanish Flu, or its virus name H1N1, still swept across the globe passing from human to human by exhaled drops of water that contained a deadly strand of RNA wrapped with a protein casing. Individuals who were unfortunate enough to come in contact with the contents of the protein casing generally developed severe respiratory inflammation, as the Immune system’s own response towards the infected lung cells would destroy much of the lungs, thus causing the lungs to flood with fluids. Due to this flooding, pneumonia was a common cause of death for those infected with Spanish Flu. Due its genetic similarity with Avian Flu, the Spanish Flu is thought to be descended from Avian Flu which is commonly known as “Bird Flu.” (Billings,1997) The Spanish Flu of 1918 has had a larger impact in terms of global significance than any other disease has had because it was the most deadly, easily transmitted across the entire globe, and occurred in an ideal time period for a disease to happen.
Researchers are also looking for new ways to improve vaccines, and they use clinical research patients to do so. Clinical patients are being tested on to see if something works in the medical practice. Before a vaccine is created the researchers behind that certain vaccine have to do clinical research studies. In these clinical trials the patient is tested and if they fit the requirements then they are eligible to take place in the study. This can help people because if the vaccines work then the vaccines can be used to help other people. Also through clinical research they can help and improve the
In 1918-19 approximately 50 million deaths were a detriment of the Spanish H1N1 virus pandemic; a respiratory virus. According to the World Health Organization, the second Influenza A H1N1 pandemic in 2009 spread to more than 200 countries causing more than 18 000 deaths. Before the World Health Organization had announced the official end of the pandemic in August 2010, in July 2009 the World Health Organization sent out a phase 6 warning that H1N1 could soon be a global pandemic. It is important to recognize that the 2 different outbreaks had different A/H1N1strains effecting the world population; this suggests A/H1N1has a high ability for mutation, severely complicating the human body’s natural immune mechanism of antigenic drift. (Qi-Shi Du et al., 2010)