Community Acquired Pneumonia Case Study

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Community acquired pneumonia (CAP), caused by viruses, ‘typical’ respiratory bacteria (as Streptococcus pneumoniae) or ‘atypical’ respiratory bacteria (as Mycoplasma pneumoniae and Chlamydia pneumoniae) is a frequent local infection in childhood (39). Pneumonia is the important cause of fatality for children around the world, accounting for about 30 percent of all childhood death. A particular pathogen is not identified in most cases, but both viruses, mainly respiratory syncytial and influenza virus, and bacteria, especially S. pneumoniae and Haemophilus influenzae, are significant pathogens(40). Numerous bacteria and viruses and their mixtures can cause this infection, but there is an absence of speedy and commercially accessible diagnostic …show more content…

Microbe-specific diagnosis, based on culture of blood, fluid or samples obtained directly from the focus of infection in the lungs, is possible only in a small minority of CAP cases. In papers published over the last 15 to 20 years, serological tests based on antigen, antibody and immune complex detection have been used for microbe-specific diagnosis of CAP in children (39, 43). Several studies are available describing the detection of lower respiratory infection etiology using PTC as a marker. Finding of these studies are not in agreement. Moulin F et al. described PCT concentration, with a threshold of 1 μg/l is more sensitive and specific and has greater positive and negative prognostic values than CRP, IL-6, or WBC cell count for differentiating bacterial and viral causes of community pneumonia in untreated children declared to hospital as emergency cases(44). The results of Toikka P et al. study indicated the quantity of serum PCT, CRP and IL-6 has little value in the differentiation of bacterial and viral pneumonia in children. However, in some patients with very high serum PCT, CRP or IL-6 values, bacterial pneumonia is feasible(45). Annick

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