Blood Transfusions and Disease

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“Blood Safety in the Age of AIDS” reflects upon the history of blood transfusions, the advancement in performing clean (disease-free) transfusions, and, specifically, the appearance of and efforts to prevent the acquired immunodeficiency syndrome (AIDS) virus in blood donations. The AIDS epidemic hitting the blood banks is not only examined as an urgent problem in its own right, but also as a warning to both doctors and patients who regularly or spontaneously require blood transfusions. This warning indicates that the idea of new diseases and epidemics are still a possibility despite medical and conditional advances through history and that additional measures should be researched in the effort to make blood transfusions less risky.

The blood transfusions started out as an already dangerous procedure during its early stages. Not only were the obvious factors of cleanliness and bacteria control an issue, but the question of blood types had yet to be raised. Despite this, some early blood transfusions were successful, such as Jean-Baptiste Denys’s transfusion of lamb’s blood into an adolescent suffering from fever in 1667. Nonetheless, many early transfusions were fatal, thus research on this procedure was halted until the nineteenth century. This research began to provide tangible hope in 1901 when the first blood group (ABO) was identified by Karl Landsteiner. This discovery explained the deaths of patients who had received an incompatible blood type. Further triumphs in medicine were achieved, such as the use of sodium citrate as an anti-coagulant and increased measures to create sanitarAs these improvements surfaced over the course of the first half of the twentieth century, the general population of the 1960s saw blood transf...

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... the engineering of synthetic blood parts, and the use of growth-factor proteins have given both researchers and patients hope. Using one’s own blood via self-donations, intraoperative hemodilution (extracting blood before an operation, then dispensing it back into the body afterward), blood recycling during surgery, and designated donations are also options for patients who wish to ensure further a clean transfusion. Finally, the practice of extracting illness-fighting white blood cells from donated blood before a transfusion may filter some diseases from the donation.

Though there were many innocent victims of the AIDS epidemic’s outreach to blood banks’ donated supply, this problem sparked new innovations and research that have worked to solve both the AIDS-infected blood problem, but also threats of other serious diseases and complications in blood transfusions

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