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The Role of Genetics in Alzheimer's
The Role of Genetics in Alzheimer's
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Where did I put my glasses? No I am sorry I cannot remember. These are the things that people with Alzheimer’s might reiterate. It is estimated that about 5.1 million Americans may have Alzheimer’s disease. Genetics is a key influence in developing Alzheimer’s, and as our population gets older, the disease impacts a greater percentage of Americans. Alzheimer’s or AD is a disease that can be lead to very severe problems and damage in the brain. Also, there is numerous studies taken place regarding the progressiveness of Alzheimer’s disease.
Age and Genetics are primary risk factors for people that acquire Alzheimer’s disease. One in ten people over the age of 65, and over half of those over 85 have Alzheimer’s disease. It is stated that over 15 million Americans will be affected by year 2050. One main reason for this is the rapid growth of the oldest age groups in the United States population. The number of individuals who are 75 to 84 years of age will double, and the number of people who are 85 years of age will quadruple believe it or not. This disease makes it very difficult for older people to go on with their daily routines. People with rare genetic changes that virtually guarantee they will develop Alzheimer’s often begin experiencing symptoms while they are in his or her 40s and 50s (Thies 2012). When people think of Alzheimer’s they often think of memory loss and an exaggeration of normal aging, which is not true. Alzheimer’s disease is more than just a disease of old age and memory failure. Alzheimer’s disease is the most common form of dementia. It is an age related, nonreversible brain disorder that develops over a period of time. People with Alzheimer’s often feel confused and lost. Also, their cognitive abilities b...
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...e effects of vitamin E and one of the drugs currently approved for Alzheimer’s, in preventing the development of the disease in people diagnosed with mild cognitive disabilities. Another research trial are examining the effectiveness of naproxen and celecoxib in reducing Alzheimer’s risk in a person who has a family history of Alzheimer’s or dementia. As scientist test these medications, the next generation of drugs is being made to target specific abnormal cellular pathways, including plaques, tangle formation, and death of brain cells. An interesting study out of Japan that looked at over one thousand men and women over the age of sixty, it was found that people with diabetes were twice as likely to acquire Alzheimer’s. Researchers are now trying to understand the molecular mechanisms that link diabetes to Alzheimer’s. It is thought that the link may be twofold
Although Alzheimer’s disease appears to be the most common cause of dementia, “more than 50 conditions are associated with dementia, including degenerative ...
Memory plays a significant role in the everyday lives of people of all ages. It allows them to recall information and remember skills that were learned in the past. Memory also organizes past information to help people make current and future decisions. However, imagine forgetting the names of close family members or not having the ability to find your keys every time you want to leave the house. These are some of the struggles that people with Alzheimer’s disease face daily. Alzheimer’s disease was first identified by German neurologist Alois Alzheimer in 1906, and was discovered to have an overpowering effect on explicit memory loss (Gruetzner, 1988). There are two types of Alzheimer’s disease – early onset and late onset. Early onset occurs in patients who are diagnosed before the age of 65 whereas late onset occurs in patients who are diagnosed after the age of 65. In the early stages of Alzheimer’s disease, short-term memory is often lost. As Alzheimer’s disease progresses, problems with long-term memory begin to develop, in addition to short-term memory impairments. Although a lot is known about the symptoms of Alzheimer’s disease, the cause has not been conclusively identified. However, as research continues, new theories about the cause of Alzheimer’s disease are being proposed. This has led to a controversy over whether Alzheimer’s disease is caused by genetics or environmental influences (Gruetzner, 1988).
Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.
... conclude that Alzheimer’s disease is becoming more common and the facts back that up. Just in a span of fourteen years the annual deaths related to Alzheimer’s has become twenty-five times greater. Both by external sources demonstrate that Alzheimer’s has been a problem for a while and will continue to increase if we do not find more efficient treatment methods in the near future.
Dementia is the progressive deterioration and impairment of memory, reasoning, and other cognitive functions occurring as the result of a disease or condition. Dementia can affect the person’s ability to carry out daily activities. For example, the person may forget where they live or they might think they have already done their activities but never did. Dementia can also cause the elderly to become incontinent and can’t control their urinary system. Many people get confused that dementia is a disease. Dementia is not a disease. However, it can lead to a disease or condition. Dementia is more common in the elderly population. It’s normal for people to forget things, but to a certain extent it becomes a critical issue. Depression also plays a role in the affects of dementia. Studies have been made to believe that the biological mechanisms for depression relating to dementia is, “interactions with vascular diseases, changes in glucocorticoid steroid levels that can result in hippocampal atrophy, accumulation of amyloid-[beta] plaques, inflammatory processes, and lack of nerve growth factors” (Heser et al., 2013). Dementia is caused because of plaques and neurofibrillary tangles. This can also be known as Alzheimer’s Disease. Dementia is the leading cause for Alzheimer’s Disease in the elderly. For all dementia cases, 60 to 80 percent of people with dementia will have Alzheimer’s Disease. The disease has 3 different stages, the early stage, the middle stage, and the late stage. Each of those stages has a variety of symptoms that affects the memory impairment of the person (Wieregna, Bondi, 2011). Also relating to dementia is Parkinson’s Disease and Huntington Disease. These diseases can result in impairment, which can cause challeng...
In the modern age scientists and researchers are constantly discovering new diseases and disorders that affect the human body. With technology improving and new equipment being introduced it enables scientists to gain more knowledge about the disorders than ever before. During the last century a German physician by the name of Alois Alzheimer linked a patient’s memory loss to her brain autopsy which displayed signs of brain shrinkage. His discovery is now known today as Alzheimer’s disease; which is a form of dementia and is a psychological disease that causes the brain to deteriorate. In today’s day and age, there are still many unanswered questions about Alzheimer’s disease (Crider, A., Goethals, G., Kavanough, R., & Solomon, P. 1989). A few known facts are that Alzheimer’s disease is it is most commonly found in elderly humans, with majority of carriers being age 60 or older. It is important to note that Alzheimer’s disease is not an old person’s disease and that it can also be found in adults of younger ages. Furthermore, there are two forms of Alzheimer’s disease. The two forms are called Early-onset which is found in adults ages 30-59 and Late-Onset which is more common and occurs in adults ages 60 and up. Alzheimer’s disease may not be curable, however with the right information it can be easy to conquer (Alzheimer and Dementia Resources).
Alzheimer’s disease, named after Dr. Alois Alzheimer, is a disease that is on the rise in America and the rest of the world. People should learn as much as they want about this disease, because as you age, your chances of becoming an Alzheimer’s Disease, or AD, patient increases. It is estimated that approximately 3 percent of Americans between the ages of 65 and 74 have the illness, and more than half of all people over age 85 have the ailment.
Alzheimer’s disease is one of the most prevalent diseases in America and in the world at this point in time and the number of cases is only increasing. Symptoms of Alzheimer’s might include a decline in mental capacity, confusion, and forgetting how to do simple tasks. The disease in not limited to the older generation but is far more prevalent. There is no existing cure for Alzheimer’s and only a few medications that can mildly treat the disease but they vary from patient to patient and are not very affective. Many people are now trying to focus on preventing the disease in its early stages. Some ways in which people do this is by pairing a healthy diet with both cognitive and physical exercises.
Alzheimer's disease is the sixth leading cause of death in the United States(1). Alzheimer's has no cure or any way of preventing it from occurring. Life expectancy continues to grow due to improvements in medicine, and so Alzheimer's Disease will continue to be a problem in the elderly. Looking at figure 1(3), it shows that from the year 2000, cases of Alzheimer's disease are estimated to double by the year 2040, which is most likely due to the fact that medicine will continue to improve. Despite not knowing the causes of Alzheimer’s, there have been studies(2 and 7) showing that high cholesterol or high blood pressure can increase the risk...
It is said that memory declines as people age, and this can be just a natural part of life. However, in many cases as people grow older, they develop a mental disorder known as Alzheimer’s disease. Alzheimer’s is a disease that causes problems with memory, thinking, and overall behavior, and progressively becomes a bigger problem. Alzheimer’s is the most common form of dementia and is a very common disease in people over the age of 65. This terminal disease puts tremendous stress on the victim and the victim’s family. A cure for Alzheimer’s has yet to be discovered; however, through healthy and constant use of the brain and the aid of certain drug treatments, Alzheimer’s disease can be both naturally and medically prevented.
Purpose – I want to bring awareness to the fact that Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills, and eventually the ability to carry out the simplest tasks.
Cummings, Jeffrey L., Cole, Greg. “Alzheimer Disease.” Journal of the American Medical Association. May 2002: 287-18. Health Source. EBSCOhost. Utica College Lib. 15 Apr 2005. .
Alzheimer’s is a disease that many people have heard of, but few really know much about. Imagine not being able to remember your loved ones and friends or even how to do simple tasks like dressing yourself and brushing your hair. Now imagine having to dress your mother, who rarely remembers you anymore. This is the reality of life for millions of older people afflicted with Alzheimer’s disease and the families that care for them. Alzheimer’s causes cognitive function to decrease gradually overtime. Alzheimer’s disease is the most common form of dementia - affecting around 5 million Americans (alz.org). It is the most fatal disease affecting older people and needs to be taken seriously.
Hello my name is Nick and I am giving my speech on Alzheimer’s Disease. I was thinking of what I could do for a speech. Then I thought I wanted to inform people on something that little know about. Then it hit me. Alzheimer’s Disease it has affected my life so much and I know so much about it. So I am going to tell you how it has affected my life in more ways than one. Before I start I want you to imagine something. Look around you know everyone right? All these faces you see practically see everyday take all that you know about them and forget it. Can you do it? I can’t. So try to imagine now that it could happen to you years down the road and the disease gets so bad you cant remember your kids, your mother, or even your family. You probably are thinking right now, it will not happen to me. Well that is what my grandfather said about 6 years ago and now he cant even remember my name.
Mykenzie Moyle Ms. Douglass English I, P.4 16 May 2014 Research Paper Alzheimer’s Disease is formed in the brain but, yet, has no known cure or treatment. Alzheimer’s disease has many symptoms. Memory is the biggest symptom along with mood swings and having a hard time keeping up with a conversation. A patient with Alzheimer’s goes through 7 stages; The first stage, which is misplacing things or forgetting what something is used for, second stage, they start losing more of their memory and they begin to forget where they are or what they are doing, the third, fourth and fifth begin to mentally decline and need someone to take care of them and worsen over time.