Urinary Tract Infection (UTI)

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Urinary tract infection (UTI) is one of the most common and frequent bacterial infections globally. It is a pathogenic invasion of the urothelium, resulting in inflammation, encompassing infections of the urethra, bladder, ureters and kidney (Dielubhanza & Schaeffer, 2011). UTI development depends on anatomical factors, the integrity of host defence mechanisms, and the virulence of the infecting organisms. Such infections affect all ages and both sexes but occur more often in women than men (Al-Badr & Al-Shaikh, 2013). Several risk factors predisposed to acquiring UTI, which includes multiple sexual intercourse partners (Lentz, 2009) and postmenopausal (Raz, 2001). According to Foster, Sr. (2008), there is approximately 60% of women experience …show more content…

Cranberry juice has traditionally been used to minimise occurrence of recurrent urinary tract infections (Howell, et al., 2010). There are several strong confirmations that cranberry can be an alternative approach to reducing UTI compare to pharmacological intervention (Santillo & Lowe, 2008). In a recent observational study (Burleigh, et al, 2013) involving 20 females with history of recurrent UTIs were enrolled in the trial and consumed sweetened, dried cranberries for 14 days. The result of the study reveals beneficial outcome from consuming cranberries, resulting in decrease number of UTIs in susceptible women (over one-half). Another study that supports cranberry consumption against UTI was conducted by Bailey, et al. (2007). The study investigated the ability of a concentrated cranberry preparation to minimise UTI occurrence. The result reveals that during the study none of the women experience UTI and no adverse effects were noted. Furthermore, Wang et al. (2013) conducted a systematic review with meta-analysis and found clinical benefits in the prevention of UTI. It also found that cranberries are relatively more effective in women with recurrent UTIs. It is apparent that evidence indicates potential beneficial effect of consuming cranberries in reducing the number of recurrent UTIs in predisposed women. However, the outcome is still uncertain due limited number of participants …show more content…

Probiotic as treatment for UTI is supported by a study conducted by Falagas, et al. (2006). The trials involving females with UTI have been conducted to evaluate the effectiveness and safety of probiotics against uropathogens. The result indicated that Lactobacillus rhamnosus GR-1 and L is the most effective probiotic for preventing UTI. It is also argued that there is association between loss of normal urogenital microflora and risk of UTI (Amdekar, Singh & Singh, 2011). Studies showed that intake of lactobacilli can modify the microflora (Reid, 2001). Lactobacilli prevent the adherence of uropathogens to the urinary tract. The argument is supported by a research study by Kontiokari, et al (2003). The study indicated that consumption of products with probiotic bacteria was associated with reduction of UTI. According to Stapleton, et al. (2011), UTI is associated with decreased of Lactobacilli and increased colonisation of uropathogens, such as E. coli. Thus, it is claimed that supplementing the vaginal flora with probiotic may prevent UTI (Stapleton, et al., 2011). However, there are some arguments arising against probiotics. McFarland (2009) includes poor quality control for some products and uncommon adverse effects of probiotics. It is supported by a systematic review (Boyle, et al. 2008), including 12 RCT with 781 participants. The

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