Background Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Acne vulgaris is a disease of pilosabaceous follicles with four pathogenic factors. These factors are follicular hyperkeratinization, increased sebum production, infection with Propionibacterium acnes within the follicle, and resulting inflammation. Follicular hyperkeratinization is increased proliferation and decreased desquamation of keratinocytes lining the follicular orifice. This results in partial obstruction of the follicle with sebum and keratin, the microcomedo. Sebaceous glands enlarge with adrenarche due to DHEA-S rise and sebum production increases. Sebum provides a growth medium for P. acnes, an anaerobic diphtheroid that is …show more content…
The drug competitively inhibits the binding of androgens to androgen receptors [Katsambas]. Additional antiandrogenic effects of spironolactone may also include inhibition of enzymatic conversion of androstenedione to testosterone, inhibition of 5-alpha reductase, and increased steroid-hormone binding globulin [George]. The drug decreases 17-beta-hydroxysteroid dehydrogenase, therefore halting the conversion of androstenedione to testosterone [Archer]. Spironolactone may also inhibit 5-alpha-reductase, thereby preventing the conversion of testosterone to dihydrotestosterone (DHT). Additionally, spironolactone may increase steroid-hormone binding globulin [Zouboulis]. Together these mechanisms of action result in a 30 to 50 percent reduction in sebum excretion [Thiboutot 2003]. In addition, spironolactone competes with aldosterone for receptor sites in the distal renal tubules, increasing sodium chloride and water excretion while conserving potassium and hydrogen ions. For this reason foods with high sodium and potassium should be avoided[Lexicomp]. Excess salt intake can be avoided by decreased intake of frozen foods, preserved foods, canned vegetables, vegetables juices, packaged deli meat, soups, marinades/flavorings, spaggetti sauce, salted nuts, chips, pretzels, ketchup, relish, and capers. Foods with high potassium levels include banana, papaya, prune …show more content…
Milk consumption has been associated with increased levels of serum IGF [Holmes]. IGF is also increased by ingestion of high glycemic loads and could potentially link diet and acne. A 12-week randomized trial that compared low and high glycemic load diets in 43 male patients with acne found a greater reduction in lesion counts with the low glycemic load diet [Smith]. However, the participants on that diet also lost more weight than those on the high glycemic load diet, so it is possible that the results were due to changes in weight rather than the composition of the diet. IGF-1 is typically found in dairy products, as well as in other foods of animal origin, such as meat and liver [Kang 2007, Ma]. A preliminary study has linked high protein diet to increased IGF. Serum IGF-1 was 35% lower in the low protein group when compared to animals fed the high protein diet. Conversely, serum IGFBP-1 was 136% higher in the low protein group compared to the high protein
Arch Dermatol. 2007;143(1):124–125. Puchenkova, S. G. (1996). "
Acne damages the skin. The bacteria and oil cause damage to the pores, skin, and underlying tissue. In response, the body sends white blood cells and other treatment molecules called collagen to the area in an attempt to heal the damaged tissues. Most acne scars only affect the outer layers of skin. Depending on how much collagen one’s body produces affects the scar type, if the scars are depressed the body does not produce enough collagen, if the scars are raised the body produced too much collagen (American Association of Dermatology 2011).
In 1957, in Germany, Dr. Karl Schulz of the University of Hamburg identified chloroacne in several workers from a Boehringer chemical plant. The disease in its mildest form resembles teen-age acne but differs in that the blackheads and cyst cluster in two locations: appearing in a crescent shape outside of and under the eyes and ears. In more pronounced cases, pus-containing spots erupt and spread across the rest of the face, neck, shoulder and down to the rest of the body.
Laliberte, Richard. "Growth Hormones in Beef and Milk." WeightWatchers.com. N.p., n.d. Web. 27 Oct. 2013. .
Androstenedione, known as "andro", is made of a naturally occurring hormone of the body, which is used naturally in tiny amounts to make the male hormone testosterone. It is found in humans, animals and the pollen of many plants. Andro is produced in the gonads and adrenal glands of all mammals. It is said to help speed up the recovery of injuries along with bodybuilding and weight training to increase muscle mass. The androgens are the male sex steroids. When andro is taken it can convert the female sex steroid, estrogen into testosterone. Testosterone increases body and facial hair, acne, deepens the voice, enhances prostate growth, and promotes muscular growth. Blood levels of testosterone start rising about 15 minutes and peak about an hour after oral consumption of androstenedione. When users take too much, androgen shuts off the bodyís own making of testosterone, which can damage normal testicular function (Quinn).
Hormone steroids used in food can have many effects on the people who eat them. Steroids in animals make the meat taste better and become lean. Even though the steroids they put in animals are edible, it does not mean they do not have an effect on those who partake of the food. The steroids in animals have a large amount of sex hormones. These steroids sometimes can contribute to cancer. They also may make girls develop early and cause them to hit puberty faster. It has been found that girls who eat foods with steroids have a higher chance of having breast cancer. People who eat dairy products that have steroids in them are increasing the risk of breast cancer. Those who eat meat products may have effects on children w...
Several effects of steroid use have been identified. These include an increase in low density lipoprotein (LDL) cholesterol and a decrease in high density lipoprotein (HDL) cholesterol. These lipid changes if allowed to continue over long periods of time could result in coronary heart disease (6). Some other side effects of steroids in men include shrinking of the testicles; reduced sperm count, infertility, baldness, development of breasts, and increased risk of pro...
Even though S. aureus is mainly associated with food poisoning, the bacterium can penetrate the skin or other mucous membranes to invade a range of tissues which will cause a variety of infections. Superficial infection of the skin can cause boils, impetigo, styes (infection of the glands or hair follicles of the eyelids), folliculitis, and furnacles. All of these infections are charac...
Besides that, vitamin C also helps in fights dandruff or some researchers and scholars claimed as seborrhoeic dermatitis. Moreover, based on the study by Ranganathan S. and Mukhopadhyay T (2010), they concluded that dandruff is considered as more towards physiological situation whereby inflammation on the scalp is reffered to seborrhoeic dermatitis. Dandruff problem is said that it is aetiologically from weak immune system and Melinda L. S. (2013) summarizes vitamin C improves in circulation system, skin health, immune system and
This treatment is considered to be effective for the removal of acne scars. This avoids the use of taking medicines and applying ointments. However, the treatment must be done by an experienced and specially traine...
Although steroids have many negative effects, they have many needed medical purposes. Androgens have many legitimate medical uses, such as the use for treatment of hypogonadal men to compensate for the lack of endogenous production. Anabolic steroids are also helpful for the treatment of certain adolescent diseases, some types of anemias, and for a relatively rare form of edema. Other clinical uses focus on the tissue building and anti-catabolic effects, such as in the treatment of burn victims, AIDS, or HIV positive patients, or patients malnourished from disease or old age (Bellino 1).
The term vegan, devised in 1944 via Donald Watson, is referred to as an individual that follows veganism, which is the exclusion of all animal products to be consumed, predominantly in their diet (Kahn, 2011). Veganism is primarily supported due to preventing animal cruelty, as well as its health benefits and environmental consequences (Craig, 2009). Adolescence is referred to as the transition from childhood to adulthood, due to biological changes that occur via the onset of puberty (Ellis, 2004). Essential nutrients that are vital to be consumed during adolescence are proteins, which are in the category of macronutrients as they are required in large amounts, as well as calcium and iron, which are categorised as micronutrients, thus being required in smaller amounts (Bialostosky, Wright, Kennedy-Stephenson, McDowell & Johnson, 2002). Protein, calcium and iron are claimed to be essential nutrients in an adolescent female following a vegan diet as they are at higher risk to be lacked via plant-based sources if the consumption of these nutrients are inadequate, which may implicate negative effects on the growth and development during the pubertal growth spurt (Craig, 2009; Ilich-Ernst et al., 1998). This essay will be regarding to a 14 year old female named Jenny Brown, whom is currently following a vegan diet and is not consuming any supplementation in order to obtain adequate nutrition. As Jenny Brown is at the age of adolescence, this essay will discuss the biological changes that occur during puberty, followed on by a discussion on each of the vital nutrients including the macronutrient protein, as well as the micronutrients calcium and iron that are essential to be adequately consumed in order to attain nutritional competence ...
...igh meat diets and cancer risk." The Proceedings of the Nutrition Society. 58(2):243-8, May 1999.
Psoriasis is a chronic skin disorder, easily identified by its symptoms of white, scaly skin and red lesions, though not so easily cured or understood. In psoriasis, skin cells mature faster than the body can shed them, causing a buildup. Although there are many theories as to what the cause of such a disease might be – genetics, stress, or other triggers – no one is quite sure why the disease occurs, or what could be a possible way to fully cure it. In this essay we will explore the symptoms, types, and effects of this condition, and also some of the known treatments.
has shot up. I think that it is fair to say that what you eat affects