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Cause and effect of smallpox
Pathogenicity of smallpox
Pathogenicity of smallpox
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Recommended: Cause and effect of smallpox
Smallpox is a very dangerous and in almost every case, fatal disease. There are two types of smallpox: variola major and variola minor. Variola Major consists of four categories ordinary (this is the most common), flat, and hemorrhagic. Variola Major only has an overall fatality rate of 30%. Flat and Hemorrhagic are the two most deadly type of Variola major. Smallpox looks like a very red, puffy, and raised rash. Smallpox is an very dangerous and contagious disease that has been present throughout history until recent times (the last epidemic case of smallpox was October 26, 1977 in Somalia).
Smallpox is an very contagious disease that lasts for about 41 days, 24 of those days are mildly to severely contagious. Variola passes from person to person through contact, prolonged face to face contact, contact with body fluids or scabs from pustules, and in extreme cases the pathogen can become an airborne pathogen. The smallpox virus is passed from human to human and it is not known if any other animals and/or insects can directly pass the variola virus to humans. There have been many cases where people have confused the variola virus with other viruses. For example S Scar Rickettsiella is an deadly disease that is nearly identical to smallpox but it is not as deadly and somewhere on the body a little scar shaped like a S (about the size of an mole) appears on the body. There is one live culture of smallpox kept in America in Atlanta, Georgia in an very secure facility. There is also one kept in Novosibirsk, Russia. Many world leaders fear that the next weapon will be biochemical terrorism. Smallpox can become an airborne pathogen which could cause the greatest amount of damage in a terror attack. From the time the virus enters into...
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...tely end the possibility of an attack doing any damage.
Works Cited
Dowshen, Steven. "Smallpox." KidsHealth - the Web's most visited site about children's health. The Nemours Foundation, 1 Jan. 2013. Web. 22 Apr. 2014. .
"More imagesSmallpox." CDC Smallpox Home. N.p., n.d. Web. 21 Apr. 2014. .
"Smallpox: MedlinePlus." U.S National Library of Medicine. U.S. National Library of Medicine, n.d. Web. 23 Apr. 2014. .
Spillius, Alex. "'We must keep smallpox stocks' US and Russia tells World Health Organisation." The Telegraph. Telegraph Media Group, 18 Aug. 1929. Web. 23 Apr. 2014. .
This summer we had an opportunity to dive into the world of bioweapons, through Richard Preston’s novel The Demon in the Freezer. His book explored the colorful world of smallpox and its use as a biological weapon. Earlier this week we were graced with this authors present for an ACES event. He discussed some of the found topics in his book such as animal testing, what small pox is, and even its eradication. One of the great things we had the chance of vocalizing were our many opinions on the gloom associated with this intriguing disease.
18) Powell, Alvin. "The Beginning of the End of Smallpox."news.harvard.edu. N.p.. Web. 13 Mar 2014. .
The Demon in the Freezer by Richard Preston is an intriguing book that discusses the anthrax terrorist attacks after 9/11 and how smallpox might become a future bioterrorist threat to the world. The book provides a brief history of the smallpox disease including details of an outbreak in Germany in 1970. The disease was eradicated in 1979 due to the World Health Organization’s aggressive vaccine program. After the virus was no longer a treat the World Health Organization discontinued recommending the smallpox vaccination. In conjunction, inventory of the vaccine was decreased to save money. The virus was locked up in two labs, one in the United States and one in Russia. However, some feel the smallpox virus exists elsewhere. Dr. Peter Jahrling and a team of scientists at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland became concerned terrorists had access to the smallpox virus and planed to alter the strain to become more resistant. These doctors conducted smallpox experiments to discover more effective vaccines in case the virus were released. Preparedness for a major epidemic is discussed as well as the ease with which smallpox can be bioengineered.
In closing, the variola virus affected a great amount in that era including, military strategy, trade, and native populations. Elizabeth A. Fenn’s book Pox Americana: The Great Smallpox Epidemic of 1775-82 sheds light on a significant aspect of that era that had not been given proper credence beforehand. She also illuminated the effect of smallpox when it came to race and social status. With regard to race, smallpox decimated much of the non European populations partly because of their lack of an innate immunity to that virus and Europeans lack of regard for those of a different race. Fenn’s argument on social status showed how the poorer strata’s of society suffered more severely from the variola virus because of their lack of finances to get inoculated; thus, the poor often suffered a worse strain of the virus which often lead to death.
Throughout the eighteenth and nineteenth century a disease dominated the world killing one in three people who caught it, smallpox. The few that survived the disease were left with very disfigured bodies and weak immune systems. In modern days this disease seems very unusual and hard to catch; it is all because of one man, Edward Jenner.
Smallpox did not play favorites when it came to choosing a victim. Whether it was a young child, or a older person, smallpox destroyed the lives of hundreds of thousands over a period of eight years in the colonies. Fenn did a great job in my opinion of describing just how bad this disease was and painted a horrific picture in explaining what people went through when dealing with the disease. Even as the author started her introduction into the book she explains that Viariola (smallpox) blinded, scarred, maimed and killed many of its victims. It is hard to even try and imagine what these individuals went through when dealing with smallpox. However, one thing is according the author they did not let the virus destroy them. They fought back with every fiber in their bodies to understand and illuminate this dreaded foe.
1. The contrast between Cottard and the other characters is that while everyone else is in constant fear of catching the plague and doing everything they can to fight the disease, Cottard is cheerful in the fact that the plague has put a stop to the police investigating his mysterious crime . Cottard probably also enjoys the camaraderie of everyone else finally being in the same position as he is.
Native Americans were completely susceptible to contracting the disease, but they weren't the only victims. Twenty people died on the Mayflower as a result of smallpox. There was a smallpox outbreak in Plymouth Colony around 1633. Twenty people died including their only physician. This was the beginning of the colonial's struggle with the disease.
In order to understand the history of smallpox one first has to understand how diseases like it evolve. Much like other species, diseases that survive in the long run are the microbes that most effectively reproduce and are able to find suitable places to live. For a microbe to effectively reproduce, it must "be defined mathematically as the number of new infected per each original patient." This number will largely depend on how long each victim is able to spread the virus to other victims (Diamond, 198).
By preserving the virus, Boylston personally inoculated 247 people in 1721 and 1722 to prevent transmission. However, from there only six people died, and Boylston was the first American surgeon to inoculate his patients personally. The author portrays the background data Boylston used to examine the inoculation practice on different age and gender of persons to treat his patients from previous experiments. The inoculation method provided higher level of immunity in preventing smallpox infection. The prevention of smallpox is through inducing antibodies through vaccines which last longer for a person taking it.
Smallpox is a highly infectious and fatal disease caused by the Variola virus. It causes extremely painful pustules to sprout across the entire body. Spread from human to human, it has since been eradicated from the world through the efforts of the World Health Organization. However, there is a distinct possibility that it may be reintroduced through bioterrorism. Biological weapons may cause another pandemic to erupt across the world and kill millions of individuals. Through constant vigilance and careful planning, mankind can prevent this scenario.
Diseases were common and widespread in the colonies. Countless times, epidemics have struck everywhere, from major cities to small countryside. Characterized by horrid rashes, smallpox was a despised disease that existed throughout history and throughout the colonies. If y...
During one of his earlier apprenticeships, Jenner noticed milkmaids with a disease called cowpox. Cowpox is a close relative to smallpox and is only mild in humans. Pustules appear on the hands and a basic cold is also brought on. At Jenner’s young age he was able to link these two viruses together and come up with a theory for immunization. In 1796, while still attending medical school, Jenner decided to test this theory between smallpox and cowpox. He used a dairymaid, who was a patient of his named Sarah Nelms, who had contracted cowpox and had ripe pustules on her hands. Jenner realized this was his opportunity to test someone who had not contracted smallpox yet. He picked an eight-year old boy named James Phipps to use as his test subject. He scraped open a spot of James' arm and rubbed in a dissected piece of Sarah Nelms pustule into the open wound. A couple days later James became ill with cowpox but was well again within a week. This test proved that cowpox could be spread between humans as well as cows. Jenner's next test would be if the cowpox virus gave James immunity against smallpox. On July 1st of 1796, Edward Jenner obtained an infected smallpox pustule and scratched the virus filled pus into James' arm. This technique of placing a virus into a patient is called variolation. James Phipps did not develop smallpox within the
Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world’s population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world’s cases occur and where eighty percent of the cases are treated at home, one in twenty children die of the disease before they reach the age of five. Pregnant women are also more vulnerable to disease and in certain parts of Africa, they are four times as likely to contract the disease and only half as likely to survive it.