Rheumatoid Arthritis Case Study

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When one is healthy there is hardly a need to visit the doctors, or a need to consistently refill medications. However, when one has an illness, especially an illness that does not have a cure, then one is obligated to go for monthly check-ups, monthly blood draws, and monthly pharmacy visits. Such is the case for Nirmal, a 52-year-old female, who has had rheumatoid arthritis for five years and hypertension since her early thirties. Rheumatoid arthritis is a chronic inflammatory disease, considered an “autoimmune disease,” and is characterized by “joint swelling, joint tenderness,” and destruction of “synovial joints” (Charles, Britt, & Pan, 2013, p. 765). She currently takes a myriad of medications which control her rheumatoid arthritis and hypertension, but the five medications that will be analyzed are: prednisone, gabapentin, methotrexate, metoprolol, and tramadol. …show more content…

127). Thus, prednisone can be utilized for an array of illnesses that involve inflammation. Prednisone is administered orally or intravenously, ranging from one milligram to fifty milligrams; however, Nirmal takes this medicine orally, once every day, in 5 milligram dosages. Prednisone is easily absorbed in the gastrointestinal tract and extensively binds to plasma proteins, such as serum albumin; however, because prednisone is “biologically inert,” it must be converted to the active metabolite prednisolone, which is then metabolized mainly in the liver and utilizes cytochrome P450 enzymes (Frey & Frey, 1990, p. 129). The half-life of prednisone is two to three hours, and is excreted in the urine as “sulfate and glucuronide conjugates” (Frey & Frey, 1990, p.

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