Pulse Wave Analysis Essay

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4.1 Overview This chapter provides some insight into pulse wave analysis and its relation to arterial diseases. The shape of the arterial pulse wave is an augmentation of the forward traveling wave with the reflected wave. The amount of wave reflection is dependent on the arterial wall properties such as arterial stiffness and is expressed in terms of Augmentation Index. This approach has been studied extensively using various measuring techniques, all of which have respective advantages and disadvantages. The purpose of PWA can be seen in the section describing the medical conditions that affect the wave shape. The discussion is included to assist the reader in understanding the purpose of pulse wave analysis. 4.2 Description of Pulse Wave Shape O’Rourke [13] describes the pulse wave shape as: “A sharp upstroke, straight rise to the first systolic peak, and near-exponential pressure decay in the late diastole.” Arteries are compliant structures, which buffer the pressure change resulting from the pumping action of the heart. The arteries function by expanding and absorbing energy during systole (contraction of the cardiac muscle) and release this energy by recoiling during diastole (relaxation of the cardiac muscle). This function produces a smooth pulse wave comprising a sharp rise and gradual decay of the wave as seen in Figure 5. As the arteries age, they become less compliant and do not buffer the pressure change to the full extent. This results in an increase in systolic pressure and a decrease in diastolic pressure. Figure 5: Example of pulse wave shape 4.3 Wave Reflection In an arterial system, the input impedance of the vessel varies with changes in the vessel’s size and properties. For compliant arteries, whic... ... middle of paper ... ...essure in the central arteries . • Hypertension: Hypertension is an abnormal increase in the systolic,diastolic or mean arterial pressure, or all three. This is due to increased arterial stiffness and can be monitored using PWA • Diabetes Mellitus: Diabetes mellitus (Type I Diabetes and Type II Diabetes) has been associated with an increase in arterial stiffness . O’Rourke’s studies showed that PWA does not aid in the diagnostics of diabetes mellitus. Further research by Cruickshank showed that PWV is a powerful independent predictor of mortality for diabetes. • Chronic Renal Failure: Savage et al conducted an investigation into the reproducibility of PWA on patients with Chronic Renal Failure (CRF). Their study concluded that indices of arterial stiffness, such as AiX and Time to Reflection (TR), which is determined by PWA, can assist in the assessment of CRF

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