Nephrolithiasis Essay

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Nephrolithiasis, also known as kidney stone, affects up to 5% of the population, with a lifetime risk of passing a kidney stone of about 8-10% (Parmar 2004).
Conforming to Melmed, Polonsky, Larsen & Kronenberg (2011) the waste products of the blood can form crystals which can collect inside the kidneys and aggregate to form stones. Normally the stones are composed of phosphate, oxalate, uric acid, and magnesium ammonium phosphate, single or combined. The type of stone is determined by the pathogenic mechanisms. When the stones are find in the bladder, ureters, renal tubules and collecting system they tend to be symptomatic. When the urine is oversaturated with the stones constituents the stones are formed. During the passage through the renal tubules the crystals aggregate into stones. In order to allow more time for growth the crystals anchor themselves to the renal tubular epithelium in the renal papillae and Randall’s plaques. The concentration of excreted ions is influenced by the diet. The intake of fluids can reduce the stone formation and growth. A reduction in the sodium int...

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