Hpvs: The Necessary Cause Of Cervical Cancer

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HPVs are now identified as the etiological factors in nearly all types of cervical intraepithelial neoplasia (CIN) and invasive cancer of the cervix. In fact, based on laboratory, clinical, and epidemiological evidence HPVs have been recognized as the ‘necessary cause’ of cervical cancer that is cancer of the cervix will not develop in the absence of persistent HPV infection.10 The relationship is stronger than that between cancer of the lung and cigarette smoking; but, the progression of cancer of the cervix from HPV infection is not inevitable. Studies have shown that only 100 000 or 10% of every one million women who are infected, progress to cervical dysplasia (that is pre-cancerous changes in cervical epithelial cells). Out of these,

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