Understanding Microgels: Significance in Drug Delivery and Nanotechnology

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1. Introduction
The term microgels are consists of two words and both these words have totally different meanings. The micro word is associated with the gel particle size. The word gel of microgel describes the swallon power of particles in suitable organic solvent [1]. So microgels contain very large molecular weight polymeric organization. Every particle of gel was existing as a particular polymer fragment. It is also define as colloidal scattering of gel molecules. The particle size of microgels should be lie from 10-1000nm [2]. The microgels plays an important role in the area of drug delivery[3]. The microgels also gains popularity in the field of nanotechnology and it enhanced day by day[4]. The greater change in their size is observed by varying the ionic strength or by applying the electric and magnetic field, by temperature and pH[5]. The particles of microgels are rounded and contains a water swallon polymeric organization [6].The amount of water for microgels are in the range from 10 to 90% which rely on the microgel diffusion chemistry. The …show more content…

These are also very helpful for the drug encapsulation which are discharge on disintegration of polymer layer network. The factors on which the physically cross linked microgels are depends are polymer composition, ionic strength of the medium and on temperature. The physically cross linked microgels are prepared from the biopolymers such as dextron, agarose and alginate[24]. This is also very important type of microgels used in many fields.

2.2 Chemically cross linked
They are covalent in nature and this property enhance their stability than the physically cross linked counterparts. The monomers are copolymerizing for the preparation of chemically cross linked microgels in the presence of multifunctional cross linking

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