Several factors affect the action of disintegrants such as: ratio of the disintegrant in tablet, particle size, molecular structure, compression force, method of incoroporation, compatibility with other excipients, adding more than one disintegrant, addition of surfactant, tablet hardness the tablets, API nature , mixing, screening and others [5,10,11]. In 1980, Rundic and co-workers found that larger CPV grades (with larger particle size) are more efficient than smaller one [12]. Later in 1981, Smallenbroek et al studied the effect of particle size of the disintegrant on the disintegration of tablet, they found that larger particle size are more efficient than smaller one [13]. Later, Rundic and co-workers studied the effect of crosslinking …show more content…
Khan and Rhodes found that SSG tablets disintegrates quickly at medium compression forces while slowly at low and high forces, this property vary with other disintegrants [16, 17]. In addition, in 1998 Munoz et al. found that the effect of compression on disintegration depend on the concentration of the SD explotab® included in the tablet. Lower SD concentration result in higher effect of compression force variation on disintegration, while at 7% where best disintegration achieved; compression force variation had a little effect on disintegration …show more content…
Fenugreek seeds contain a high percentage of mucilage which swell when hydrated [10,33]. Kumar et al used fenugreek mucilage at multiple percentages to prepare metformin FDT and compared it to other SDs. At 4%, the mucilage gave better disintegration time than the most widely used synthetic SDs like CCS [34]. Avachat et al reported the use of of fenugreek husk for granulation [35]. 1.3. Soy polysaccharide (Emcosoy®) It doesn’t contain any starch or sugar and used in nutritional products (figure 4). It has a good swelling ability and can act as tablet disintegrant [5]. In 1982, Khalidindi et al evaluated soy polysaccharide as a disintegrant in directly compressed tablet and compared it to crosslinked sodium carboxy-methyl cellulose and corn starch, they found that soy polysacchardie showed a good disintegrant activity similar to those of 2% cross-linked carboxy-methyl cellulose and 8% superior to corn starch [36]. 1.4. Lepidium sativum Mucilage Also known as asaliyo, it belongs to Cruciferae family. It has a good availability and low cost. The plant seeds contain high amount of mucilage which act as binder, disintegrating agent and gelling agent
In the U. S today, the approximated population of undocumented immigrants stands at averagely 11 million. Therefore, this has created a hot debate in Congress about the action to take over the undocumented immigrants. Those opposed to illegal immigrants suggest that, their stay in the United States effects U.S citizens on the job market negatively . In addition, illegal immigrants are viewed in certain quarters as takers in the sense that illegal immigrants benefit more from public resources than the american-born citizens of the U.S. However, the reality is that immigrants contribute positively to the U.S economy and pay significantly into the system compared to what they send back home. In addition, the contributions associated with undocumented immigrants involve sustaining the solvency of the SSTF (Social Security Trust Fund). In this sense, the use of cost benefit analysis by those supporting immigration restrictions are unfounded and do not reflect the facts on the ground (Nadadur 1037). The opponents of undocumented immigrants believe that having more undocumented immigrants in the U.S is costly; however, there are no solid reasons to prove that undocumented immigrants are a burden to the treasury. Instead, the undocumented immigrants play an important role in boosting the economy and in particular by taking up jobs those citizens perceive as demeaning because the money they earn goes back to the economy through taxes resulting from consumer spending when they send money back home.
The United States has been known as the “Melting Pot ”and “The Land of Opportunity” for decades, but the title is slowly diminishing as scrutiny has been bombarding immigrants for wanting a better life. As questions arise of what is needed to protect the borders from possible terrorist other factors come into play such as what immigrants have to contribute to the country. Immigration is actually vital to our country since it provides the government more income, it brings the country a positive image, and DACA helps the community come together.
In the United States, it is practically impossible to walk down most streets without coming across a homeless person. The issue of homelessness has worsened because of the number of veterans back from our most recent wars. They have resorted to homelessness as their only refuge after being unable to maintain a stable home and/or not receiving the treatments they need. But as veteran homelessness demands more attention, especially in California, various solutions are being brought to action. The “housing-first strategy” being offered to homeless veterans and those endangered of becoming homeless, has played a major part in moving California closer to having an end to veteran homelessness in 2015.
U.S. immigration law is very complex, and there is much uncertainty as to how it works. The Immigration and Naturalization Act (INA), the body of law governing current immigration policy, provides for an annual worldwide limit of 675,000 permanent immigrants, with certain exceptions for close family members ("How the United States Immigration System Works: A Fact Sheet"). Around the world there are so many immigrants/refugees who are in the hunt for a fitter life. Some come from places where civil war occurs or some suffer economically trying to support their family. Knowing the fact that they are desperate to seek for a better life, the best option is to migrate to the U.S, the land of opportunities. The problem lies in the migration to the U.S. What are the quotas for new immigrants arriving to the U.S? What are the eligibility requirements to becoming a permanent citizen in the U.S? With much inquiry, this topic has become very intriguing. What people must understand is that
The homeless population is growing in America. There are more and more Americans living in boxes, sleeping on park benches and panhandling on the streets each day. These people tend to make us, the non-homeless, feel uncomfortable and unsafe. They are also placing increasing stress on the nation's economy. In short, the homeless are a burden on the rest of society. There needs to be action taken against them. "I shall now humbly propose my own thoughts, which I hope will not be liable to the least objection (Swift.)" I propose that all of the homeless be relocated to foreign third world countries. They can then be hired in American factories producing shoes, automobiles and other various goods at less than one dollar per hour.
The policies implemented by the United States to strengthen the border and enforce immigration policies have led to the abuse and profiling of undocumented immigrants. Undocumented immigrants live in constant fear of deportation and are subjected to multiple human rights violations as they are abused, exploited and discriminated against. Immigrants are racialized and stereotyped. The US government has passed laws that discriminate against undocumented immigrants, making it harder for them to live and survive in America. These laws are due to the perception that undocumented immigrants are a burden on the US economy, but on the contrary undocumented immigrants provide an economic benefit to the US, and due to the benefit they provide society
Immigrants were first welcomed in the late 1700s. European explorers like Walter Raleigh, Lord Baltimore, Roger William, William Penn, Francis Drake, John Smith, and others explored to the New World for religious purposes and industrial growth. The first European settlers that settled in the late 1700s were the Pilgrims. After the Pilgrims first settled in Virginia, the expansion of immigrants started. Then in 1860 to 1915, America was growing with its industries, technology, and education. America’s growing empire attracted many people from Europe. The factors that attracted many people to the American cities where job opportunities with higher income, better education, and factory production growth. As the population grew in the American
In this essay, I will be talking about social work problems faced in the UK and how they are addressed. I will be focusing on asylum seekers particularly Unaccompanied asylum seeking children (UASC). These are children who are under 18yrs of age and applying for asylum in their own rights. I aim to highlight key areas in understanding the needs of these children while recognising that these are by no means homogenous, and therefore explain how these needs are addressed by social policies, legislature and social workers.
Many people debate on weather homeless people should receive guidance or just be abandoned. Do homeless people deserve our service and to be supported, or are they just lazy individuals trying to take advantage of people? Homelessness is a growing dispute in cities. It has became an extensive problem for the community. Homelessness can not and should not be ignored. The number of homeless people in the United States is quickly growing. It seems like no one cares to help them. Even our heroes like police officers show no sympathy towards the homeless. “Homeless people appeared on the streets of Bucharest in 1990. Since then, their number and the problems created by this phenomenon have steadily increased in all major
For centuries, migrating has been a life changing decision for people that choose to enter the United States in search of a better future. Therefore, immigration is the permanent residency of people that choose to move to a new country. There are debates concerning the immigrants who enter the United Stated illegally and as the daughter of immigrant parents, I am fortunate to be born in this country.
Immigration has always been a large conflict people have faced all across the world. There are plenty of reasons why people migrate to a country, whether it may be the United States or any other particular one. Many people often come in an attempt to escape poverty, crime, or to simply have a better opportunity to better their lifestyle. Although there are people who migrate and commit severe crimes, there are others who sacrifice themselves in order to live a better life. In addition to that, I believe the government should approve new immigration laws in favor of immigrants who come to better their life and achieve their dreams.
Today, in most cases, people don’t spend very much time thinking about why the society we live in presently, is the way it is. Most people would actually be surprised about all that has happened throughout America’s history. Many factors have influenced America and it’s society today, but one of the most profound ways was the way the “Old Immigrants” and “New Immigrants” came to America in the early to mid 1800s. The “Old Immigrants were categorized as the ones who came before 1860 and the “New Immigrants” being the ones who came between 1865 and 1920. The immigrants came to the United States, not only seeking freedom, but also education. Many immigrants also wanted to practice their religion without hindrance. What happened after the immigrants
The population of Los Angeles continues to grow each day because people perceive that the opportunities will improve their economic and social well-being. Most of them get good jobs manufacturing, business and the government giving them the ability to provide for themselves and their children. Those who are not lucky enough do not realise their goals and depend on the government and the society for basic needs. The effort of the city and the government to house the homeless cannot take the pressure of the rising number of the homeless without the support of the society. Los Angeles in the United State’s largest urban and has the highest number of homeless people making the task of housing its population next to impossible without participation
The solubility of a substance is defined as its ability to dissolve. There are some factors that alter solubility, such as pressure and the type of solvent, but will temperature affect the solubility of a substance? The investigation problem is to identify whether or not the temperature of a substance affects its ability to dissolve in another substance. Understanding solubility and the processes that undergo is very important, this is due to the important role that it plays in our daily life as well as in the human body. When it comes to oral ingestion, especially in drug delivery, it is profitable since it permits to deliver the medicine throughout the system in order to gain positive and desired responses. Meanwhile it is seen in the human body, it is also manifested while doing household cleaning and in automoviles. That’s why it is essential to recognize and know what is solubility in order to be able to control, manipulate, and enhance it as well as get informed of how life works by depending on water and chemical reactions.
Destitution is craving. Destitution is absence of asylum. Destitution is being debilitated and not having the capacity to see a specialist. Destitution is not having the capacity to go to class, not knowing how to peruse, not having the capacity to talk legitimately. Destitution is not having work, dread for the future and living without rushing too much. Destitution is loosing a tyke to ailment achieved by unclean water. Neediness is feebleness, absence of flexibility