Controversies around the use of Monosodium glutamate in food

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Monosodium glutamate (C5H8NO4Na) also known as MSG is an organic compound derived from glutamic acid that is used as a flavour enhancer for food. Glutamic acid or glutamate is a naturally occurring non essential amino acid that combines with sodium ion to form MSG. Glutamate is produced naturally by our bodies and is also found in meats and vegetables that we eat (Health Canada, 2008, Para. 1). MSG is an odorless, white crystalline compound in its pure form. MSG on its own has a taste similar to salt, but when it is added to a dish the natural flavour of the food itself is enhanced. The functional groups associated with MSG are an amine group and two carboxyl groups. MSG readily dissociates into sodium and glutamate ions in water and saliva. Discovered in 1908 by a Japanese chemist named Kikunae Ikeda who isolated the compound from seaweed, MSG quickly found its role in the food industry. Ikeda describe this new taste as being different from the four pre-existing flavours known as: sweet, bitter, salty, and sour. He named this new flavour umami which meant pleasant savory taste (Rouhi, 2003, Para. 6). In 1909, MSG was introduced into the market under its trade name of Ajinomoto in Japan. As time passed, the manufacturing process of MSG transitioned from the extraction from seaweed to large scale industrial fermentation of molasses extracted from sugar canes and beets to accompany with the increasing demand (Rouhi, 2003, Para. 4). Today, MSG can be found in many processed foods and fast food restaurants. MSG has been used in various recipes around the world for well over a century. It is one of the most studied food additive in human history and throughout this period there have been numerous documented studies done on it...

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6. Rouhi, A. M. (2003, July 28). C&EN: SCIENCE & TECHNOLOGY - Monosodium Glutamate. Retrieved March 17, 2014, from https://pubs.acs.org/cen/whatstuff/stuff/8130sci3.html
Stanford University (2011, June 11). About Glutamate Toxicity « HOPES. Retrieved March 17, 2014, from https://www.stanford.edu/group/hopes/cgi-bin/wordpress/2011/06/about-glutamate-toxicity/

7. U.S. Food and Drug Administration (2012, November 19). Questions and Answers on Monosodium glutamate (MSG). Retrieved March 17, 2014, from http://www.fda.gov/food/ingredientspackaginglabeling/foodadditivesingredients/ucm328728.htm

8. Zeratsky, K. (2012, April 3). Monosodium glutamate (MSG): Is it harmful? - Mayo Clinic.
Retrieved March 17, 2014, from http://www.mayoclinic.org/healthy-living/nutrition-and-healthy-eating/expert-answers/monosodium-glutamate/faq-20058196

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