the digestion of macronutrients

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Since humans are heterotrophs, they rely on the food they eat to provide their bodies with the energy needed to carry out vital cellular functions. Humans require six essential nutrients for survival: water, vitamins, minerals and three macronutrients; carbohydrates, lipids and proteins (Bowers et al, 2002). These macronutrients are often ingested as polymers, long chains of repeated basic molecular units called monomers, which are too large to be absorbed by cells directly. The digestive system is responsible for breaking these polymers down into monomers so that the nutrients can be absorbed into the bloodstream and transported throughout the body. This breakdown of nutrients is achieved through mechanical and chemical digestion. Mechanical digestion for all macronutrients begins in the mouth and it involves the physical breakdown of food through tearing, chewing, mixing and churning (Bowers et al., 2002). Mechanical digestion prepares the food for chemical digestion by increasing the surface area upon which the digestive enzymes can act (Bowers et al., 2002). In chemical digestion, polymers are broken down chemically through the process of hydrolysis with the aid of digestive enzymes which accelerate the process (Collin County Community College, 2014):

Protein + water protease amino acids
Complex sugar + water carbohydrase simple sugars

Fats + water lipase glycerol + fatty acids

Polymers are formed during dehydration synthesis reactions, as a covalent bond forms between two monomers when a water molecule is lost (Collin County Community College, 2014). In hydrolysis, the covalent bond between monomers in a polymer is broken by the addition of a water molecule as the hydrogen in the water molecule attach...

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...nzymes to digest them. In chemical digestion, hydrolysis breaks the bonds between monomers with the aid of enzymes, secreted throughout the digestive tract and by the accessory organs, to catalyze the process. These enzymes functional optimally in certain areas of the alimentary canal based on the pH of the surroundings. The monomers of carbohydrates and proteins are then absorbed into the mucosal cells of the microvilli lining the small intestine and diffuse into the capillaries surrounding the villi where they are transported in the bloodstream to cells in the body. Most of the nutrient absorption occurs in the duodenum and jejunum (University of Illinois Chicago, 2004). Lipids are too large to diffuse into the capillaries and are reassembled into triglycerides and enter the lymphatic system. Any undigested matter is eliminated from the digestive system as feces.

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