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Penicillin in pharmacology
Penicillin and its impact on treating disease
Was science the main factor in the development of penicillin
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Penicillin is an antibiotic that kills bacteria, sufficiently treating any injuries. This drug was invented before the war, but had its major outbreak during World War II. Once scientists discovered the potential of penicillin, they aggressively started to pursue methods to mass produce the drug. The mass production of penicillin saved many American lives and led to our victory during World War II.
Penicillin, derived from the mold Penicillium, is the first antibiotic to successfully treat bacterial infections on humans. It was accidentally discovered by scientist, Alexander Fleming. While Fleming was growing Staphylococcus, a serious and often deadly infection, in a dish, he noticed the bacteria had stopped growing after a mold found its way
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It kills bacteria by competing with it for food, The bacteria around the fungus are destroyed as penicillin is released. The penicillin kills the mold by stopping its cell walls from forming. This results in the cells bursting and dying (Ward, 50-51). During World War II, penicillin was used in place of surgery due to the lack of doctors. The drug obviated the need for many amputations because it could neutralize the bacteria that caused dead tissue responsible for limb removals (Conniff, 2013). A letter sent home from a soldier, Murphy, demonstrates an example of this. “At first they thought they would have the take his leg off… it was long before they really could treat him… But they started treating him with the new ‘wonder drug’ penicillin and it brought him around ok” (Higginbotham, 2001). In addition to eliminating amputations, penicillin made infections less painful to handle. Surgeons commonly treated wounds by draining them and leaving them open to heal. Infections were common and often deadly, recovery wound take months. However, after the distribution of penicillin, surgeons simply drained the wound, sprinkled penicillin powder, and stitched the wound close (Conniff, 2013). Thousands of soldiers who escaped death or amputation owed their well-being to the mass production of
The Factor of War in the Development of Penicillin The discovery, development and subsequent use of penicillin can be considered to be one of the most important breakthroughs in medical history. There were many factors, which were involved in the development of penicillin, and it could be argued that war was the most important, but other factors were also responsible. Alexander Fleming was working in London as a bacteriologist in 1928 when he noticed that a growth of a mould called penicillin produced a substance that actually killed the germs he was working on. He realised that this might be very important and a year later he wrote an article about his findings. However, Fleming did not have the facilities or the support to develop and test his idea that penicillin could fight infection, and he didn't develop it further.
History has proven the use of chemical weapons ranging back for decades. From the Greeks in ancient Europe using Greek fire to South American tribes using a form of tear gas made of grounded up hot chili peppers to scare away enemy tribes. As well as dipping the tips of spear heads with a poisonous toxin. Poisonous toxins used from live reptiles like frogs and venom from the snakes found from whichever region had enough potency venom to exterminate. The past has proven, that in order for Armies to survive and win, it relied on out smarting the enemy. New technologies and the evolution of weaponry were left to the brightest minds from those eras to develop.
The WWP was started in 2003 to raise awareness and enlist the public's aid for the needs of severely injured service members; to help severely injured service members aid and assist each other; to provide unique, direct programs and services to meet their needs. The WWP is worthy of support because its mission is to help wounded vets and soldiers in the field with monetary support, jobs, and gatherings to have them meet their supporters.
Medicine has developed so dramatically over the last century that it is difficult to imagine a world in which its many benefits did not exist. Even as humans manage to eradicate some diseases, a look at history reminds us that there was a time when these and other diseases were rampant, and good health was the exception rather than the norm. There are many comparable time periods that medicine was needed and was used. With each, there were drastic changes to medical procedures and medical rules. Of the many different time periods that medicine was used; the comparison of medical care during the American Civil War and medical care during World War I is the most interesting. How did Civil War battlefield medicine compare with World War I battlefield medicine? That's a question that cannot be simply answered, but can be broken down into the overall sanitation of individuals, medical techniques, and overall medical staff for armies.
The Medical advancements of WWI had a huge impact on the war; many soldiers’ lives were saved due to advances in medicine and the invention of the ambulance. The First World War had many casualties and deaths, many of these deaths were not caused by the “invisible soldier”. Most of the injuries in the war were caused by large explosions and gunshot wounds. With the invention of the ambulance, many soldiers were aided sooner rather than later, resulting in their lives being saved.
Before World War II, medicine and medical practices in the United States was lacking and ineffective. This made it so the majority of fatalities in war were not caused by trauma but by diseases. Diseases were often caught and incurable because of the lack of medical expertise the United States retained, causing death rates to be high. In war, diseases would wipe out soldiers before bullets were even fired. In the early 1930’s when the great depression started, the U.S was at its lowest point. Because of the poor state the United States was in, medical advancements were at a stop. Medical advancements with blood transfusions, vaccines, and antibiotics made it so the U.S strengthened as a whole. These medical advancements on the battlefield Reduced the loss of life in World War II.
World War II, global military conflict that, in terms of lives lost and material destruction, was the most devastating war in human history. It began in 1939 as a European conflict between Germany and an Anglo-French coalition but eventually widened to include most of the nations of the world. It ended in 1945, leaving a new world order dominated by the United States and the USSR.
Years later other scientists were also intrigued by the possibilities of penicillin and produced enough penicillin to prove that it was a useable antibiotic. The scientists from Great Britain were developing all of this during World War II, and unfortunately funding for their drug was unavailable due to the war. They decided to bring their concepts to the United States, and once enough was made, it was eventually used, to treat wounded soldiers during World War I.
Have you ever wondered what it would be like in the middle of a war? If so, The War that Saved My Life is a historical fiction book that takes you on the journey of nine year old Ada Smith and her younger brother, Jamie. In my opinion, The War that Saved My Life, is one of the best books I have read and it shows that despite the obstacles in life, there is always a positive outcome. Ada was born with clubfoot, is in the middle of World War II, has a mom that is ashamed of her foot. However, Ada does not let these things get in the way, and solves these problems into a new life.
Many Americans assume that medical professionals are generally helpful of others. However, a controversial question has been raised about the use of medical professionals and their involvement with torturing enemy combatants during war. Is it morally right or morally wrong for them to be involved in these sorts of practices? I believe that medical professionals who are involved in overseeing and treating tortured enemy combatants are morally praiseworthy. Medical professionals are praiseworthy because its undoubtedly correct for a medical professional to help preserve the life of tortured. Furthermore, medical professionals are praiseworthy because their job description demands that they assist injured people. Lastly, I emphasize that medical professionals are correct by performing these practices because it makes the doctors patriotic. I also will address a few opposing viewpoints within my points expressed and relate back to how my points outweigh the opposition.
Penicillin is the reason people lived healthy and long lives. Sick, cold, and sore, are feelings people have when they are sick. If people were to become sick and penicillin was not around they would have those feelings for a longer duration. Penicillin was an idea that belonged to a famous scientist by the name of Sir Alexander Fleming. Penicillin was just the slightest of idea in Fleming’s mind after he married his wife who had the profession of a nurse. Fleming made penicillin after conducting test on accidentally infected fungus inhabited plates. He tried washing the fungus of with disinfectant, then he noticed a yellow-green zone around the fungus. He came up with the conclusion that penicillin’s main goal would be to eliminate the outer weak ring
To provide proper patient education there first needs to be an understanding of the history of antibiotics. “Alexander Fleming identified the mold Pecicilium notatum, which inhibited the growth in certain bacteria. Examples of these bacteria re Staphylococcus aureus, haemolytic streptococcus, pneumococci, and meneingococci. In 1929, he published his findings suggesting that penicillin could be used for treatment but he made no further progress.”(141-142)
Discovery and Development of Penicillin. (2014, April 4). Retrieved from American Chemical Society International Historic Chemical Landmarks: https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html
Thesis: With the advent of antibiotics in 1929 Fleming said, "The time may come when penicillin can be bought by anyone in the shops.Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant."With the overuse of antibiotics today we have seen this very idea come to be.Over usage is caused most prevalently by a lack of education on the part of the patient.Thus stated, the way to overcome such a circumstance is to educate, not only the patient but also the physician.
The discovery of antibiotics is attributed to Alexander Fleming who discovered the first antibiotic to be commercially used (Penicillin) in approximately 1928. An antibiotic, also known as an antimicrobial, is a medication that is taken in order to either destroy or slow the growth rate of bacteria. Antibiotics are integral to the success of many medical practises, such as; surgical procedures, organ transplants, the treatment of cancer and the treatment of the critically ill. (Ramanan Laxminarayan, 2013)