Synthetic biology, also known as synbio, is a new form of research that began in the year 2000. The Action Group on Erosion, Technology and Concentration (ETC Group) says that synthetic biology is bringing together “engineering and the life sciences in order to design and construct new biological parts, devices and systems that do not currently exist in the natural world’ (Synthetic Biology). Synthetic biology is aiming to create safer medicines, clean energy, and help the environment through synthetically engineered medicines, biofuels, and food. Because synthetic biology has only existed for fourteen years, there is controversy involving its engineering ethics. In this literature review, I am going to summarize and correlate the International Association for Synthetic Biology (IASB) Code of Conduct for Gene Synthesis, the impact of synthetic biology on people and the environment, and the philosophical debates.
Nine years after synthetic biology was first practiced, the IASB finalized the Code of Conduct for Best Practices in Gene Synthesis. They said that “this event is a breakthrough in self-regulation in synthetic biology” (“Code of Conduct for Best Practices in Gene Synthesis). IASB’s code gives engineers and scientists the freedom to research organisms and genes that may hold environmental or health risks, but in a safe and secure manner. IASB addresses the possibility that synbio materials could be used inappropriately, for instance, in terrorist activities. Engineers and scientists are expected to follow previous “standards of good practice” set forth in the general engineering code of ethics and perform risk assessments of DNA sequences for genes. “Records of suspicious inquiries” and “statistics on biosecurity and bios...
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...follows the general code of ethics, but it only has one specific code of ethics for gene synthesis. This worries many people because they cannot see synthetic biologists’ ethical procedures and how these researchers would apply these rules in different situations. In time, there will be an agreed upon code of ethics for synthetic biology and this will help relieve people because they will believe that valuable, but possibly dangerous, information is less likely fall into the wrong hands and that appropriate experimenting occurs. The goal of synthetic biology is to improve medicine and protect the environment. Synthetic biologists want to cure cancer, provide new energy sources, and more sustainable foods. People’s concerns are legitimate and need to be analyzed, but until these ethical concerns and possible risks are addressed synthetic biology cannot move forward.
In the late twentieth century, the field of biotechnology and genetic engineering has positioned itself to become one of the great technological revolutions of human history. Yet, things changed when Herber Boyer, a biochemist at the University of California, founded the company Genentech in 1976 to exploit the commercial potential of his research. Since then the field has exploded into a global amalgam of private research firms developing frivolous, profit-hungry products, such as square trees tailor-made for lumber, without any sort of government regulation.
Threshold 5 tackles the beginning of life on Earth. This is where any living things are characterized by metabolism, homeostasis, and reproduction. Over time, the genetic makeup of any living thing change so later generations being slightly different. This results into diversification and the evolution of certain species that best suit their environment. However, threshold 5 also deals with the idea of dealing with the “natural world.” It may seem that the environment is almost entirely man-made but the “natural world” is still a huge part of the environment. This can be simple as the earth on the ground, the air that people breathe in, or even the sun that provides the heat and light to the planet. However, as human technology progresses the “natural world” becomes less and less apparent in the world today.
Genetic engineering depends on the location and analysis of genes on chromosomes and ultimately DNA sequencing. The early cartography of the genes used the principles of Mendelian genetics . It is assumed that alleles that are transmitted together side by side are located on the same chromosome : it is said that are connected or linkage . These genes form a bridging group - linkage group : are the same for gametes and are usually transmitted together , so they do not have independent distribution. Crossing-over occurring during meiosis may cause these alleles can be exchanged between the chromosomes of a homologous pair .
Shortly after the groundbreaking discovery of the structure of DNA in 1953, the scientific world was essentially given the ability to alter the genetic sequence of any living organism using a process known as 'genetic engineering'. By definition, genetic engineering is 'the deliberate modification of the characteristics of an organism by manipulating its genetic material', it is quite simply an unnatural process which defies the ordinary course of nature. As of yet, no devastating or permanent damage has been done. However, the unpredictable nature and unknown consequences genetic engineering holds is more than enough reason to be cautious, as one mistake could have irreversible and catastrophic effects.
Although humans have altered the genomes of species for thousands of years through artificial selection and other non-scientific means, the field of genetic engineering as we now know it did not begin until 1944 when DNA was first identified as the carrier of genetic information by Oswald Avery Colin McLeod and Maclyn McCarty (Stem Cell Research). In the following decades two more important discoveries occurred, first the 1953 discovery of the structure of DNA, by Watson and Crick, and next the 1973 discovery by Cohen and Boyer of a recombinant DNA technique which allowed the successful transfer of DNA into another organism. A year later Rudolf Jaenisch created the world’s first transgenic animal by introducing foreign DNA into a mouse embryo, an experiment that would set the stage for modern genetic engineering (Stem Cell Research). The commercialization of genetic engineering began largely in 1976 wh...
Science and technology are rapidly advancing everyday; in some ways for the better, and in some, for worse. One extremely controversial advance is genetic engineering. As this technology has high potential to do great things, I believe the power genetic engineering is growing out of control. Although society wants to see this concept used to fight disease and illness, enhance people 's lives, and make agriculture more sustainable, there needs to be a point where a line is drawn.
Human Genetic Engineering: Designing the Future As the rate of advancements in technology and science continue to grow, ideas that were once viewed as science fiction are now becoming reality. As we collectively advance as a society, ethical dilemmas arise pertaining to scientific advancement, specifically concerning the controversial topic of genetic engineering in humans.
Reading up information and searching for clues (which were not extremely easy), turns out to have broadened my knowledge on Nature and Biomimicry itself and that there are so many people already using wind turbines to harvest the winds energy and know how the world can be saved. Therefore I have come to the conclusion and have seen that my hypothesis has been proven right.
Before we begin to delve into the ethical depths of biotechnology and genetic engineering, we must first understand how this technology works. To do this let’s start by discussing cells. All organisms are made up of microscopic entities called cells. The human body consists of about ten trillion cells of about two hundred different types, such as skin cells, blood cells, and muscle cells. To gain a general understanding of how cells work, we will look at some of the simplest cells possible- bacteria cells. Once we have an understanding of how bacteria work, it is not hard to see how cells function in other organisms.
Synthetic biology is the genetic engineering of an organism in able to alter the characteristics, traits, and task that it is not naturally supposed to. The goal of synthetic biology is to create new life forms by inserting computer-generated DNA sequences into living cells, and then breeding them to produce offspring. Unlike biology and chemistry, which are meant to be understood, synthetic biology is used to change the way something works. "Whereas standard biology treats the structure and chemistry of living things as natural phenomena to be understood and explained, synthetic biology treats biochemical processes, molecules, and structures as raw materials and tools to be used in novel and potentially useful ways, quite independent of their natural roles. It joins the knowledge and techniques of biology with the practical principles and techniques of engineering." The process of synthetic biology involves extracting the genetic makeup of one organism and inserting it into another organism. This all started in 1971 when Ananda Chakrabarty patented a bacteria genetically engineered ...
The controversy of these issues stems from the immense potential in genetic sciences for both positive use and harmful misuse. Though the questions and fears of critics reflect the wisdom of caution, the potentially unlimited benefits mandate that we pursue these technologies.
Due to the fact that the field of biotechnology is very serious and potentially dangerous, rules must be set down in order to keep the research in check. The high risk research of genetic therapy needs guidelines that have to be followed in order to keep the study just. The articles that are discussed in this essay focus on ethical issues and ideas that should be followed in the field in order to keep research safe and valid.
We as humans should determine the end line of the scientific process of discovery when it begins to result in bad things in concerns that may affect our species, nature, and our way of life. This is due to problems with gene doping, horizontal gene shifts could give increase to other pathogens, and the concern of animal welfare within genetic engineering.
The field of biotechnology is absolutely huge. There is the medical area and agriculture area of development. The agriculture area concentrates on developing hybrid crops and manipulating genes so that the plants natural defenses activate. Although this is interesting and has an effect on our lives, I have chosen to concentrate on the medical aspect of biotechnology. I have also decided not to comment on the ethics of the new developments, since I believe that the reader should decide for oneself. More specifically, the concentration will be on the Human Genome Project, artificial organs, and companies that are involved in the biotech industry.
Scientists and the general population favor genetic engineering because of the effects it has for the future generation; the advanced technology has helped our society to freely perform any improvements. Genetic engineering is currently an effective yet dangerous way to make this statement tangible. Though it may sound easy and harmless to change one’s genetic code, the conflicts do not only involve the scientific possibilities but also the human morals and ethics. When the scientists first used mice to practice this experiment, they “improved learning and memory” but showed an “increased sensitivity to pain.” The experiment has proven that while the result are favorable, there is a low percentage of success rate. Therefore, scientists have concluded that the resources they currently own will not allow an approval from the society to continually code new genes. While coding a new set of genes for people may be a benefitting idea, some people oppose this idea.