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Pancreatitis pathophysiology
Chronic pancreatitis case study
Quizlet patients with acute pancreatitis
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Recommended: Pancreatitis pathophysiology
The pancreas is the organ of the upper part of the abdomen that is about 6 inches long
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The flattened head of the pancreas is surrounded by part of the small intestines called the duodenum and the body lies behind the stomach with the rest of the tail in front of the left kidney. The main functions of the pancreas is to secrete alkaline juice with enzymes, amylase and lipase, and secrete insulin and glucagon. Amylase and lipase helps diges t fats, protein, and carbohydrates from food that we eat. The alkaline j uices secreted helps neutralizes the acid secretions of the stomach, and the stomach secretes about 1.5 liters of the alkaline juices in a day.
The insulin and glucagon is essential for the regulation of the glucose
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Other symptoms can include nausea and vomiting, tenderness of the upper abdomen, tachycardia, and fever. A person experiencing chronic pancreatitis will go through the similar symptoms of acute pancreatitis too.
There will be constant pain in upper abdomen, and people can be disabling due to severe pain, weight loss caused by poor absorption of food, oily, smelly stools and a loss of appetite.
A lot tissue damage causes th e lack of digestive juices to malabsor ption to cause oily and fatty stools.
Causes
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Gallstones and heavy alcohol use, medications, infections, trauma, metabolic disorder, cy stic fibrosis, high triglycerides can cause acute and chronic pancreatitis. Roughly, about 15% of the cause of acute pancreatitis is unknown, and 20% to 30% cause of chronic pancreatitis is unknown.
P
seudo
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cysts that block the ducts can cause chronic pancreatitis
Hereditary conditions can be a result of chronic pancreatitis.
Diagnoses
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Doctors can diagnose pancreatitis by measuring levels in blood of two digestive enzymes, amylase and lipase. High levels of these digestiv e enzymes suggests acute pancreatitis and during inflammation, it is raised three times above its normal
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To measure the damage to the cells in the pancreas that make insulin, a glucose tolerance test is done.
Ultrasound, CT scan, and MRI are also done to reveal any swelling and damage to the gland. A white blo od cell (WBC) count can also show elevated cell count. For more severe cases of
PANCREATITIS
4 pancreatitis, doctors may order urine, blood, and stool tests to asses the deficiency of enzymes, and confir m diagnoses and extent of the damage. Sometimes biopsy are performed to get a sample to study.
Treatment
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To treat pancreatitis, people usually seek care in the hospital for five to seven days depending on the severity of the acute pancreatitis. Patients would be hooked up to
IV fluids, and pain medications to help ease the pain and to prevent de hydration. Surgery is an option, and is most likely to remove dead pancreatic tissue, to remove gallstones
, or if pseudo
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cyst formed during the inflammation, an incision to the pancreas is done to drain the cysts. With pseudo - cysts, it can cause breathing difficult y, so a ventilator therapy can help with severe lung
Diabetes is a disease that causes an abnormally high level of sugar, or glucose, to build up in the blood. Glucose comes from food we consume and also from our liver and muscles. Blood delivers glucose to all the cells in the body. In people without diabetes, the pancreas makes a chemical called insulin which is released into the blood stream. Insulin helps the glucose from the food get into cells. When the pancreas doesn’t make insulin, it can’t get into the cells and the insulin stays in the blood stream. The blood glucose level gets very high, causing the person to have type one diabetes.
I. Introduction: It is estimated that approxiamately 10 to 20 percent of the population in the United States and Western Europe are currently being affected by Gallbladder attacks.
Acute pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) appears to be the most frequent major complication, occurring in 1-10% of patients overall, with a mortality rate ranging from 0.2-0.6% and an annual healthcare expenditure cost reaching $150 million in USA alone (1) (2). Several risk factors have been reported to play a role in ERCP-induced pancreatitis; some are patient-related (i.e. sphincter of Oddi dysfunction (SOD), female gender, history of pancreatitis, pancreatic acinar opacification), while others are procedure-related (i.e. precut or needle-knife endoscopic sphincterotomy, repeated pancreatic duct injection, difficult cannulation), and this may be useful in stratifying patients into low-risk or and high-risk categories (3).
Crohn’s disease is an inflammatory bowel disease. It is a fairly common disease that affects a large population causing abdominal pain, frequent bloody stools, and fatigue
The most common of these is the adenocarcinoma, which begins in the ducts of the pancreas and makes up about 95% of the exocrine cancers. When you think of the repercussions of smoking, you often think of lung cancer, but smoking also increases your chances of getting pancreatic cancer by almost 50%. You are twice as likely to get pancreatic cancer if you smoke than you would if you didn't. In addition, overweight people are twenty percent more likely to develop pancreatic cancer. Pancreatic cancer can also be hereditary, and you can be at a higher risk because of an inherited syndrome.
The pancreas is an elongated and flattened gland located within the abdomen. Not only is it a vital part of the digestive system, but it is also a key controller of blood sugar levels. (The Pancreas). The pancreas has been divided into four regions which are the head, neck, body, and tail. Being the widest part of the pancreas, the head is twenty-three millimeters. The part of the head that hooks towards the back of the abdomen is the uncinate (Chronic Pancreatitis Imaging). Between the head and body of the pancreas is the neck, which is about nineteen millimeters. The body of the pancreas is twenty millimeters, between the neck and the tail. The tail is the smallest part of the pancreas, measuring at only fifteen millimeters. (Parts of the Pancreas). The length of the pancreas in total ranges from four point seven to seven point one inches. The pancreas also weighs from seventy to one-hundred grams (How does the Pancreas Work?).
The pancreas can be divided into two sections when studying the histology. The pancreas has exocrine and endocrine functions, each with unique cell types. The exocrine pancreas serves to secrete digestive enzymes into the duodenum. Some of the specific enzymes and secreted substances are Proteases, lipase, amylase, bicarbonate, and water (Bowen, “Exocrine Secretions”). These enzymes are used to break down protein, fat, and carbohydrates respectively. The bicarbonate simply act as an acid buffer to prevent damage of the small intestine as the stomach acid must be neutralized. The enzymes are created in acinar cells and the bicarbonate is synthesized in epithelial cells surrounding pancreatic ducts (Bowen “Exocrine
Diabetes is a disease in which a person’s body in unable to make or utilize insulin properly which affects blood sugar levels. Insulin is a hormone that is produced in the pancreas, which helps to regulate glucose (sugar) levels, break down carbohydrates and fats, and is essential to produce the body’s energy. The CDC (2013) offers reliable insight, summarized here, into the different types of diabetes, some causes, and health complications that may arise from the disease.
Fig1. shows the human digestive system or the alimentary canal with different organs. (ladyofHats 2006).
When the blood glucose is higher than the normal levels, this is known as diabetes disease. The body turns the food we eat into glucose or sugar and use it for energy. The insulin is a hormone created by the pancreas to help the glucose get into the cells. The sugar builds up in the blood because either the body doesn’t make enough insulin or can’t well use its own insulin (CDC, 2015). In the United States diabetes is known as the seventh leading cause of death. There are different types of diabetes. However, there are two main types of diabetes and these are; Diabetes type 1 and Diabetes type 2 (CDC, 2015).
The pancreas is located in the middle of the abdomen. It’s surrounded by the stomach, small intestine, liver and spleen. It’s about six inches long and shaped like a thin pear, wide at one end. It has three sections: wider right end is the head, the middle is the body and the left end is the tail.
Diabetes is a disease that I came across when researching my maternal side of my family history. Diabetes is a disease that affects your pancreas an important organ in regulating blood sugar. When a person has diabetes there are two ways it can affect the pancreas because there are two types of the disease. Type-1 diabetes affects the pancreas by not allowing the body to produce enough insulin to keep the body’s blood sugar at a healthy number. The opposite is for Type-2 which produces too much insulin and gives the body too much insulin keeping the blood sugar number above healthy (Type-2).
“Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the body can't use glucose (a type of sugar) normally. Glucose is the main source of energy for the body's cells. The levels of glucose in the blood are controlled by a hormone called insulin, which is made by the pancreas. Insulin helps glucose enter the cells” (Diabetes Mellitus).
The pancreas is one of the essential organs in the human body and belongs in the Digestive system. Out of all the internal organs, the pancreas is unique because the pancreas plays a role in both the endocrine gland and the exocrine gland. This means that the pancreas is a dual function gland in which is the reason why the pancreas is such a vital part of the digestive system. This research paper will talk about the anatomy, physiology, and the important functions the pancreas play to maintain homeostasis.
Pancreas – The pancreas is located deep in the abdomen. The function of the pancreas in the endocrine system is to produce two hormones called insulin and glucagon. These two hormones maintain balance (homeostasis) in the blood sugar. The insulin produced enables the glucose that is created from the breakdown of carbohydrates to be used in the cells as energy. Glucagon raises the glucose level in the blood.