Coronary Artery Dissection Essay

393 Words1 Page

Introduction: Spontaneous coronary artery dissection (SCAD) has been reported in 0.1 to 0.4 percent of cases presenting with acute coronary syndrome (ACS). It is particularly common in young women. Risk factors include multiparity, post-partum state and collagen vascular diseases. We present a case of SCAD in a patient who had undergone orthotopic heart transplant (OHT). Case: A 71-year old female presented for routine post-transplant surveillance angiogram. She had undergone OHT for non-ischemic dilated cardiomyopathy from a young female donor 7 years ago. Previous annual surveillance angiograms were normal and endomyocardial biopsies had not revealed cellular or humoral rejection. This angiogram revealed normal right coronary, but an intraluminal filling …show more content…

Left main artery was normal, so it was unlikely that the diagnostic catheter engagement caused traumatic dissection. She denied any chest discomfort and electrocardiogram showed no ischemic changes. Intravascular ultrasound was not performed due to the risk of worsening of the dissection flap in an asymptomatic patient with no evidence of ischemia and normal distal flow. Serial cardiac markers and electrocardiograms were unremarkable. Echocardiogram revealed no regional wall motion abnormalities with a normal left ventricular ejection fraction. The patient was observed in the coronary care unit and treated with dual antiplatelet therapy. She had an uneventful hospital course. Discussion: SCAD is an uncommon cause of ACS. Patients lack the traditional risk factors for atherosclerotic coronary artery disease but certain populations have been identified. This patient had received OHT from a young female which could be a contributing factor for the development of SCAD. The absence of angina in heart transplant recipients is due to denervation of the graft. Although corticosteroids may be a risk factor, the majority of OHT recipients are weaned off by 6

Open Document