Celiac disease is a genetically determined autoimmune disease characterized by mucosal inflammation caused by an intolerance to gluten, a protein found in wheat, rye, and barley (Green et al.. 2007). The disease has a classical association with gastrointestinal symptoms such as abdominal pain and constipation and it is said to affect approximately one percent of the population (Miśkiewicz et al. 2012). Frequently the disease is accompanied by weight loss, anemia, weakness, and bone disease. Celiac disease has also been associated with reproductive dysfunction in women, such as recurrent miscarriages, alternations in the menstrual cycle, and infertility (Sóñora et al. 2011).
Reproductive dysfunction is when there is an abnormality in the reproductive organs causing one to have difficulties reproducing. In general reproductive dysfunction is said to affect men and women equally. Women that suffer from reproductive dysfunction tend to have complications in conception and pregnancy.
The increased prevalence of celiac disease in women who suffer from reproductive dysfunction has been studied. Unexplained infertility in women who suffer from celiac disease has been described since the 1970’s (Pellicano et al. 2007). Women that suffer from celiac disease have an unexplained infertility rate that is 2.5-3.5% higher than normal women (Pellicano et al. 2007). Women who suffer from celiac, whether treated or not, tend to have recurrent miscarriages and infertility (Ana Paula de Souza Machado et al. 2013). Low birth weights and a shorter duration of breast feeding have also been seen in women who suffer from celiac disease (Green et al. 2003). The link between celiac disease and reproductive dysfunction in women has been studied, but there is no known mechanism for this association.
Researchers have been trying to understand the mechanism connecting celiac disease and reproductive dysfunction for many years. Studies have been conducted on the content of celiac patients’ sera, tissue transglutaminase (tTG) activity, and genotype. When studying celiac patients’ plasma, also known as serology, elevated amounts of IgA-specific antibodies(define) were seen (Sóñora et al. 2011). These antibodies react with tTG(define) and, even though they are mainly localized in the jejunum, but can also be found in the liver, muscle, brain, and heart. Antibodies that are tTG-specific can also affect the activity of enzymes, the permeability of endothelial cells, the development of new blood vessels, cell differentiation, and proliferation of cells.
Tissue transglutaminase is a multifunctional enzyme that is expressed in most tissues and in every cellular compartment.
Shakeology ingredients do not contain gluten. There are some clients who complained about developing celiac symptoms after drinking Shakeology though. They may have bought a pack that was contaminated with gluten. They could also be allergic to some of the ingredients in gluten. If you have celiac disease, it is advisable to exercise caution. You could begin by using half of the dosage. If it does not work for you, remember there is a money back
When someone first finds out they have Crohn’s disease, they will probably feel overwhelmed. There are so many questions. Will I be able to work, travel and exercise? Should I be on a special diet? Could my medications have side effects? How will Crohn’s disease change my life? The better informed they can become, the more equipped they will be to be an active member in your healthcare (Crohn’s & Colitis Foundation of America, 2009).
As you know autoimmune diseases are your immune auto-generate antibodies against cells of your body. In here, I don’t tell physiology of autoimmune diseases but I will tell one of most autoimmune diseases that is immune fertility disease. Researchers at the University of Virginia Health System have found a new human protein, radical radial spoke protein 44 (RSP44) in July, 2007. RSP44 is antigen can be found in all men, residing in the sperm tail at the center of a structure known as the axoneme. Antigens can only stimulate antibody production when they come in contact with components of the blood. Under normal conditions, blood and sperm do not mix. Direct contact between the two is prevented by a cellular structure in the testes called
Celiac Disease is an inflammatory disease that destroys the lining of the small intestines and prevents the absorption of nutrients and vitamins into the system. The patients' health suffers; their digestive system is unable to process gluten foods that contain wheat, barley, and oats. The cause of this disease is unknown; however, environmental factors and a genetic predisposition are suspected.
Gluten is a protein found in common grains such as wheat, barley, and rye. Those affected with allergies to these foods (the most serious allergy being Celiac Disease) must follow a strict gluten-free diet in order to experience relief from their symptoms. Despite eliminating the ingestion of the allergen, gluten-free individuals begin to suffer from adverse side effects. In recent years, many Americans have begun to live an entirely gluten-free lifestyle with no medical necessity to do so. Many believe it to be a healthier diet, and even more believe it is an effective weight-loss tool. With this growing fad of adopting a gluten-free diet, under the false pretenses of varying health benefits, many Americans are exposing themselves to unnecessary health risks, over-priced and narrowly available foods, and an overall depletion of dietary needs.
In Vitro Fertilization (IVF) is a complex series of procedures used to help those who want children but struggle with infertility. The process consists of extracting eggs from a woman and collecting a man’s sperm sample then manually combining them in a lab dish. Once the embryo(s) are created they are transferred to a woman’s uterus. IVF is commonly used in woman who cannot conceive on their own due to different reasonings. “These include but are not limited to blocked or damaged fallopian tubes, male factor infertility, woman with ovulation disorders, genetic disorders, woman who have had their fallopian tubes removed and unexplained infertility.” (American Pregnancy)
What is Crohn’s Disease – Aimee Rouski Inspired Published on June 5, 2016 in Health What is Crohn’s Disease? See the recent post by Aimee Rouski on Facebook. I became curious about Crohn’s Disease.
According to the Centers for Disease Control and Prevention, 2.1 million married couples experience troubles with infertility. Infertility is defined as trying for over a year and not becoming pregnant for women under 35 and trying for six months for women over 35. The cause of the infertility is a male factor one third of the instances, female another third, ten percent of the cause is a combination of both male and female factors and the remaining twenty percent is not apparent. In vitro fertilization is a process that tries to eliminate the problems inherent in the mother and father. It involves an egg is fer...
The pathogenesis of CD relies on a complex interplay between a triad of factors: genes, gluten, and environment – all of which work together to result in the disease’s characteristic injury of the small intestinal mucosa, ultimately resulting in nutrient malabsorption.3 HLA-DQ2 and HLA-DQ8, both of which are HLA class II genes, are the main predisposing genetic factors that are displayed in nearly all patients with CD. 3 Many other non-HLA genes are thought to play a role in the development of CD in distinct patient populations, but their role is not nearly as universal as that of the HLA class II genes. The way in which gluten plays a critical role in CD pathogenesis is the fact that both gliadin and glutenin are rich in proline and glutamine peptides, which effectively renders the gluten proteins resistant to proteolytic degradation by gastric, pancreatic, and intestinal brush border enzymes.5 This inadequate digestion will result in the generation and collection of large peptides high in proline and glutamine content in the small intestine.
Infertility is defined as “not being able to become pregnant after a year of trying. If a woman can get pregnant but keeps having miscarriages or stillbirths, this too is known as Infertility” (NIH: National Institute of Child Health and Human Development). It is a growing problem, year after year the number of people effected increase. “Infertility affects
Gluten consumption during late pregnancy and risk of celiac disease in the offspring: the TEDDY birth cohort
According to various studies, it has been found that somewhere close to 5 to 10% of women of fertile age are affected by PCOS. It has also been found that the condition
“Managing Infertility.” USNews.com. Stanford University Medical Center, 31 Mar. 2007. Web. 22 Mar. 2010. .
The cause of endometriosis continues to remain unknown. It has been researched for many decades and...
Nutrition is the hallmark and determinant of development and growth in all organisms, and it is all the more paramount during the gestational period when new life is about to born. During gestation, maternal nutrition plays a direct, pivotal role in fetal growth; maintaining proper nourishment for the mother is not only vital for the overall health of the mother in anticipation of delivery, but also in the regulation and development of the fetus, which in turn determines the offspring’s long-term health and condition. With adequate available nutrition, the fetus can subsequently attain its growth potential and be born at an appropriate birth weight and in good health. Undernourished pregnant mothers, however, are at higher risk of contracting