Rewinding to the root of the problem is unchecked cell reproduction for that is from where cancer arises. A cell manages to avoid the regular checks intended to monitor the cell’s normal development, resulting in it dividing continuously through mitosis until the abnormal cells aggregate to form a mass/primary tumour at the site of the initial cancer progression. At this point, these cells are not invasive nor metastatic, yet they may accumulate genetic alterations as they reproduce, giving them such capabilities. Metastasis may then occur as the cancer spreads to other organs by invading the circulatory or lymphatic system.
Once afflicted with the disease, there are many forms of cancer management. The specific type of treatment prescribed depends on each individual case, taking into account the disease’s stage, the tumour’s location and size, and the patient’s health. The fundamental aim of the cancer treatment is to rid the body entirely of the cancerous cells while doing as little harm as possible to the normal cells. To increase the efficacy of this, severa...
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...iver. Thus it can cause diseases such as pericarditis, myocarditis, or hepatitis. This single-stranded RNA virus also possesses cytolytic capabilities. Specifically coxsackievirus B3 was shown to demonstrate tumour selectivity for non-small cell lung cancer. Thus, it is a viable candidate in treating lung adenocarcinomas, both localized and metastasized.
The advent of new, more effective weapons are indispensable in defeating this long-time foe. Agents with increasing prominence and paramount capabilities to incur this change are oncolytic viruses. They, either naturally or through genetic engineering, have the capability to specifically target and kill tumour cells and only tumour cells, even if the cancer has proceeded to the metastatic stages. Advancements in this progressive field may very well be instrumental in bringing about the turning point of this war.
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