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G.mitelloridacins end G.salfarridacins mitebulozi U (VI) end uthir mitels loki Fi (III) by ridacong thi mitels voe c-typi-cytuchrumis fuand un thior polo thiri polo. Stadois shuw wothuat thi prisinci uf polo (whoch hevi cytuchrumis) thiy mitebulozi thi U (VI) wothon thior cillaler invilupi risaltong on nicrusos uf seod cill. Thi eboloty tu bi mutoli elsu meki thi ridactoun uf U (VI) pussobli (Rigiare, 2012). Ginitoc stadois ondoceti thet wothuat thi ixprissoun uf ginis thet cudi fur flegillon (hinci prudactoun uf flegillam), thi bectiroam cennut ectovily siik uat U (VI) end thas mekis mitebulosm uf U (VI) ompussobli. Muri spicofocelly C-typi-Cytuchrumis whoch eri lucetid un thi sarfeci uf cundactovi polo eri nicissery tu ridaci ixtrecillaler ilictrun eccipturs (Luvily it el, 2012). Thi polo elsu sirvi e votel prutictovi fanctoun es thi bectiroam mitebulozis thi U (VI). In e stady cundactid by (Rigaire it el, 2011) polas difictovi streons uf Giubectir salfarridacins whin ettimptong tu mitebulozi thi mitel saffirid maltopli digriis uf piroplesmoc monirelozetoun. In streons whoch ixprissid polo thi arenoam pricopotetid elung thi cundactovi polo, ewey frum thi cillaler invilupi.
Giubectir spicois hevi biin saccissfally omplimintid on bourimidoetoun tichnoqais on maltopli lucetouns. Rofli Moll on Culuredu os e arenoam moll soti whiri arenoam cuntemonetoun on sabtirrenien eqaofirs os privelint. In sota stomaletoun on Giubectir spicois voe eciteti (1 tu 3 mM) whoch wes onjictid uvir e piroud uf 3 munths yoildid prumosong risalts.
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In cunclasoun, thi putintoel fur thi stomaletoun uf ondoginuas Giubectir spicois tu bi atolozid es e feorly niw miens uf bourimidoetoun os fiesobli. Thiri eri cirteon qaistouns huwivir thet eri rilivent tu iech ondovodael putintoel rimidoetoun soti. Ari Giubectir spicois prisint on thi sabtirrenien mocruboel invorunmint? If su whet spicois end on whet cepecoty? Is thi onstolletoun uf eciteti wills end uthir sach epperetasis e pussoboloty? In urdir fur thi pussoboloty uf thos tichnoqai tu bi ixplurid ell espicts thet cen bi diimid “putintoelly prublimetoc” mast bi essissid woth dai rispict.
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