shape of it will lead to abnormality to our health. According to Elaine N & Katja H (2008 anatomy and physiology pp 642) Anemia “is a condition in which the blood’s oxygen carrying capacity is too low to support normal metabolism” which has multiple tips like Sickle cell anemia, Aplastic Anemia, Iron-Deficiency anemia and pernicious Anemia. Today will focus on pernicious Anemia and the relationship with vitamin B12 deficiency, Zollinger-Ellison syndrome and total gastrectomy,
methionine from homocysteine and participa... ... middle of paper ... ...its role as a coenzyme for L-methylmalonyl-CoA mutase and methionine synthase (e). Serum vitamin B12 less than 145 pg/mL is considered deficient, and is commonly caused by pernicious anemia and atrophic gastritis (k) (h). B12 is measured with a competitive-binding immunoenzymatic assay that measures concentration based on an inverse relationship to absorbance (i). Methylmalonic acid and homocysteine are associated metabolites
Cobalamin deficiency, occurs frequently among elderly people. Vitamin B12 is a nutrient that helps keep the body's nerve and blood cells healthy and helps make DNA, the genetic material, in all cells. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak. Often times, the symptoms of this deficiency are undetectable because the signs are subtle. This creates several issues including identifying those at risk for deficiency and providing those individuals
deaths globally each year from iron deficient anemia alone (Collaborates, 2015). However, more than base mortality rates have to be considered when assessing the true impact of anemia on public health. For those with prolonged undiagnosed cases of mild to moderate anemia the long term effects to their health are hard to calculate. New understanding of the mechanisms of cellular systems has led to advancements in identification and treatment of anemia. Each advancement is another step in understand
The most common blood disorder in the united states is. Anemia is when a person doesn’t have enough red blood cells (RBC’s) or hemoglobin in their blood to carry enough oxygen to the body cells. Anemia affects woman more than men and many types of anemia can be prevented. The causes for anemia include: Iron deficiency, chronic blood loss, vitamin B12 deficiency, side effects from medications, chronic diseases, bone marrow disease. Iron deficiency is when there is not enough iron. Chronic Blood loss
The Hematologic System is regarded as the body’s system that regulates the movement of nutrients, molecules (macro and micro molecules), and oxygen to tissues and metabolic waste products and carbon dioxide out of the tissues (Colbert, 2009). The overall role of the hematologic system is to deliver substances needed for cellular metabolism, temperature regulation, defend the body from injury and microbial infections, and maintain the homeostatic balance or acid-base chemistry of the blood and fluid-electrolyte
minor, thalassemia intermedia, and thalassemia major. The topics relating to beta thalassemia that are going to be explored are inheritance patterns, genes, mutations and proteins involved with Beta Thalassemia. Thalassemia also known as Cooley’s anemia (Catlin 2003) was originally described by Thomas Cooley in 1925 (Starr 2012). The name Thalassemia came from the Greek name for sea (thalassa). This was due to the fact that for many years, those who had been most affected lived in the vicinity of
suffering is the most common type of anemia, Iron Deficiency Anemia. Iron deficiency occurs when red blood cells (RBCs) is lower than normal in the body. The protein is answerable for carrying oxygen in the body’s tissues, which is important for body tissues and muscles to function successfully (Oxygen at altitude,2009). Short of sufficient iron the hemoglobin is not producing enough making someone become anemic, several causes can develop iron deficiency anemia, such as breast breastfeeding, menstruation
Anemia is a condition in which the body has a low number of red blood cells in the body. Anemia is also known as blood disease that occurs when the blood of the person does not have enough hemoglobin. Hemoglobin iron-rich protein that gives blood its red color. It also helps the human body to transport oxygen from the lungs to the body. There are different causes of anemia, but there are preventions and treatment as well. The causes of anemia depends highly on the type of anemia that the person
I would like to begin by saying I have been a Laboratory technician for over ten years now and have worked at my current job for over three years. I began my internship with the feeling that I would not have anything to write or say about the experience but I was wrong. I started out with the blood bank department. I work my weekends in that department, we are assigned a department for weekend rotations. My supervisor is also the blood bank department supervisor. I came to the Houston Medical Center
The Blue people of Troublesome Creek, sounds like a title of fiction novel, but the Blue Fugates were no fictional characters, but they were real humans that lived not too far from where we are today. The Blue Fugates were a very close family live on the banks of eastern Kentucky's Troublesome Creek. Martin Fugate, a French orphan settled in Troublesome Creek and astonishingly Martin somehow managed to find a woman who carried the same, very rare disease. The disease, later discovered, was methemoglobinemia
Anemia happens when blood lacks enough healthy red blood cells or hemoglobin. Hemoglobin is the main part of the red blood cells, and it’s what helps bind the the oxygen to the blood. If your blood cells or hemoglobin isn’t normal, then your body cells will not get enough oxygen like they should. They’re are also multiple types of Anemia, such as Sickle cell Anemia. Sickle cell is one that only affects african Americans. Iron deficiency is another name for Anemia. Anemia affects every single organ
(HS). The most common cause of HS is the mutations in the gene encoding the membrane protein ankyrin-1 (Gallagher, Steiner, Liem, Owen, Cline, Seidel, Garrett, & Bodine, 2010). Hereditary Spherocytosis is the most common form of inherited hemolytic anemia in the US, northern Europe, and notably in Japan, affecting one person in 2000. HS can be found in most racial groups, but it is less common in African American and south Asia... ... middle of paper ... ... 1999). The role of band 3 protein in
blood cells enter the spleen the cells undergo hemolysis. Hemolysis in hereditary spherocytosis results in the interplay of an intact spleen and an intrinsic membrane protein defect (Medscape). The breakdown of red blood cells is called hemolytic anemia (Wint Carmella). A normal red blood cell can live up to one hundred and twenty days. A red blood cell with the membrane defect might live ten to thirty days. When the child d... ... middle of paper ... ...oms that come along with it. There is
Malnutrition is both a cause and a consequence of ill-health. The term malnutrition can apply to various states – under-nutrition, over-nutrition or deficiencies of specific nutrients (8).Malnutrition is common but under-recognised in the elderly. Clinicians are seldom taught about the subject during their undergraduate or postgraduate level.Malnutrition can lead to serious consequences in terms of morbidity and mortality (5).Undernutrition is a global problem that is usually caused by a lack of
Anemia is a disease that is commonly seen in veterinary medicine. This disease can be described as having low amounts of red blood cells and a reduced amount of hemoglobin in the circulating blood, which reduces the oxygen-carrying capacity of the blood. It develops from loss, destruction or lack of production of red blood cells. Anemia is usually a secondary disease caused by another disease or medical condition. There are three different types of anemia; regenerative, non-regenerative and relative
and having less hemoglobin leads to anemia. Alpha globin and beta globin are the proteins that create Hemoglobin. A defect in the gene that helps control production of alpha or beta goblin leads to Thalassemia. Fewer blood cells leads to anemia, which is the common culprit in Thalassemia. The most common forms of the differing Thalassemias are Alpha-Thalassemia and Beta-Thalassemia. Thalassemia is also commonly known by Cooley's anemia and Mediterranean anemia. Alpha Thalassemia is when genes related
had pale mucous membranes, a weak pulse, a dull coat, and was lethargic. Laboratory Investigations In response to the findings from the physical examination, several diagnostic techniques are required to determine the diagnosis of the suspected anemia (Fleischman, 2012). The required tests are packed cell volume measurement, a reticulocytes count, blood smear examination and a completed blood count. The packed cell volume, which measures the percentage of red blood cells present in the blood, can
Sickle Cell Anemia is an inherited blood disorder that is extremely challenging to live with. Its symptoms are many, with the most prominent being severe pain that can become unbearable to the point where hospitalization is required. Because sickle cell is a genetic disorder, a person is born with it and it is usually permanent. Unfortunately, there are risks and complications associated with this disease. However there are various treatment options for a patient with sickle cell and also support
kinds of cells in the blood, especially red blood cells, platelets, and white blood cells. A complete blood count helps your doctor check for any symptoms, such as weakness,bruising or fatigue. It also helps him or her diagnose conditions, such as anemia which is a decrease in the amount of oxygen carrying substance found in red blood cells, infection, and many other disorders. A complete blood count test usually includes platelet count, white blood cell count, red blood cell count, hemoglobin, red