Intercept Pharma Canada files New Drug Submission to Health Canada for Marketing Approval of Obeticholic Acid for the Treatment of Patients with Primary Biliary Cholangitis Obeticholic Acid represents first new treatment option for Primary Biliary Cholangitis in 20 years NEW YORK, NY, September 15, 2016 – Intercept Pharmaceuticals, Inc. (Nasdaq: ICPT), a biopharmaceutical company focused on the development and commercialization of novel therapeutics to treat non-viral, progressive liver diseases
Inflammation could be defined as a medium by which the body tissues respond to all sorts of injury (Roitt, 1997). It is a defence mechanism against infection from injuries. Physical stimuli such as change in temperature, UV radiation, or skin irritation may cause release of inflammatory mediators such as cytokines that ensure the immune system provide suitable defence, chemokine that bring leukocytes to the inflammation site, eicosanoids, neuropeptides, etc. Inflammation could be acute or chronic
Multiple Sclerosis (MS) is an autoimmune disease. It is a chronic and disabling disease of the brain and central nervous system (the spinal cord). An autoimmune disorder is a disorder caused by the reaction of an individual’s immune system against the organs and tissues of the body. In MS, “when a certain part of the myelin sheath (nerve cover) is inflamed and damaged, transfer of impulses through neutrons, is disturbed, slow or intermittent" (Tanovis, Vrabac, Kadic, Rama, Tanovic, 2014). This means
adherence. larger scale studies that employ prospective objective methods are necessary to gain a better understanding of adherence patterns in multiple sclerosis. Multivariate analysis showed that the odds of adherence were significantly higher in the natalizumab cohort. so why don't people just understand that they need to take the right amount of medicine they need and go to the doctor for tips on alternative medication that they need to have.
Introduction According to National Multiple Sclerosis Society, Multiple Sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system (CNS) that disrupts the flow of information within the brain, and between the brain and body. The central nervous system (CNS) comprises of the brain and the spinal cord. CNS is coated and protected by myelin sheath that is made of fatty tissues (Slomski, 2005). The inflammation and damage of the myelin sheath causing it to form a scar (sclerosis)
Multiple sclerosis, also known as MS, is one of humankind’s most mysterious diseases. No one knows the exact cause and there is no exact treatment. Still multiple sclerosis has the ability to affect nearly 3 million people worldwide and at least 500,000 people in the United States (Boroch). This disease tends to be more common in individuals of northern European descent and women are more than twice as likely to develop multiple sclerosis as men. Of those 3 million people, most of them are between
Multiple Sclerosis (MS) is “a chronic, degenerative, progressive disease of the central nervous system characterized by the occurrence of small patches of demyelination in the brain and spinal cord” (Smeltzer & Bare, 1996). Over 2 million people are diagnosed with MS and it is known that there is a link between geography and the diagnosis of this disease (Faguy, 2016). In personal interviews with the patient and his wife, discussions were held about the disease process for this patient; medications