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    Myasthenia Gravis

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    Myasthenia Gravis Myasthenia gravis is believed to have been discovered as early as 1672 when Thomas Willis, wrote in his book De Anima Brutorum, that "a woman who temporarily lost her power of speech and became 'mute as a fish.'".(Abboud, 1996). Another early description of this disease is documented in colonial correspondence with England. "The excessive fatigues he encountered wrecked his constitution; his flesh became macerated; his sinews lost their tone a warrior chief. He had an elasticity

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    Myasthenia Gravis

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    According to Medical-Surgical Nursing: 7th edition, Myasthenia Gravis (MG) is an autoimmune disease that can be considered as a chronic neuromuscular disorder (Lewis et al., 2007, p. 1555). MG is caused by an autoimmune process in which “antibodies attack acetylcholine (ACh) receptors, resulting in a decreased number of ACh receptor (AChR) sites at the neuromuscular junction” (p. 1555). Due to the neurotransmitter’s inability to connect the muscles and the nerves, it is difficult for the muscle to

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    Pathogenesis of Myasthenia Gravis

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    dictionary: Myasthenia gravis is " a disorder of neuromuscular transmission marked by fluctuating weakness and fatigue of certain voluntary muscles, including those innervated by brainstem motor nuclei; caused by a marked reduction in the number of acetylcholine receptors in the postsynaptic membrane of the neuromuscular junction, resulting from an autoimmune mechanism."(8) Myasthenia gravis comes from the Greek and Latin words meaning "grave muscular weakness."(1) Myasthenia gravis is an autoimmune

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    Myasthenia Gravis Essay

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    Historically, Myasthenia Gravis was discovered by Thomas Willis in 1672. It was not until late 19th century that Wilhelm Erb and Samuel Goldflam described the muscle disease due the lack of nervous input. Initially, it was called the Erb-Goldflam syndrome until Friedrich Jolly, a German neurologist coined it as Myasthenia Gravis Pseudoparalytica. He created the Jolly test, which tested for muscle weakness by eliciting faradic stimulations for continuous muscular contractions that caused fatigue (Ropper

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    Myasthenia gravis is an autoimmune disease that effects the skeletal muscles of the body at the neuromuscular junction. The 40th Edition of Gray’s Anatomy defines it as, “myasthenia gravis is essentially an autoimmune disease in which acetylcholine receptor proteins of neuromuscular junctions are attacked by autoantibodies.” (Gray’s). This chronic disease is characterized by muscles that fatigue quickly activity and gets better after rest. The muscles that are most often effected are those that control

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    Introduction Myasthenia Gravis is a chronic autoimmune disorder that weakens the muscles. The name MG comes from the Latin words meaning grave muscle weakness. In 1672, Thomas Willis was the first to describe a patient with myasthenia gravis. There were periodic case descriptions over the years in 1900 regarding this disease. The disease remained a mystery, until 1960 when Simpson suggested that myasthenia gravis was caused by antibodies against the acetylcholine (ACh) receptor. Patrick and Lindstorm

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    Diagnosis and Treatment of Myasthenia Gravis

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    MYASTHENIA GRAVIS contents Topics……………………………………………………………………………page number • Introduction…………………………………………………………………………………2 • Epidemiological information………………………………………………………………2 • The normal functioning of an organ and Pathogenesis of the disease……………………………………………………………..2 • Symptoms………………………………………………………………………………….2 • Diagnosis…………………………………………………………………………………..3 • Treatment………………………………………………………………………………….3 • Conclusion………………………………………………………………………………...4 • References………………………………………………………………………………

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    and age groups, and all ages. Myasthenia Gravis was first discovered in 1877 by Samuel Wilks (Basel). Myasthenia Gravis affects the muscular system due to a defect in the neuromuscular junction which causes symptoms like ptosis, but ultimately can be controlled and treated. Myasthenia Gravis is a disease that occurs in the muscular system, causing weakness of the muscles due to a problem at the neuromuscular junction. First, the system affected by Myasthenia Gravis is the muscular system which consists

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    Myasthenia gravis (MG) is a chronic state that causes muscles to tire and weaken easily. The meaning of the term Myasthenia Gravis is broken up, My means Muscle, asthenia means lack of strength and Gravis means serious. In an autoimmune disorder the immune system attacks parts of the body. The part of the body that is attacked by the circulation of antibodies, is the muscular system, and in certain receptors for acetylcholine on muscle cells at the neuromuscular junctions. An overview of the disease:

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    Myasthenia Gravis

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    been observing several cases of a neuromuscular disease that they believed was affecting how nerve impulses were transmitted to muscle at the neuromuscular junction. The patient’s experienced a "grave muscular weakness" and Wilhelm named it myasthenia gravis. Through further research, the physicians discovered whether it affected the eye muscles first, or created difficulty in talking, chewing and swallowing, or in using the arms and legs it was neither hereditary nor contagious. Their discoveries

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