Free Metabotropic glutamate receptor Essays and Papers

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    Admissions Essay - From Farming to Medicine I heard the familiar sound of the back door closing gently. My father was returning from driving his dirty, green John Deere tractor in one of our fields. Although he begins his day at 5:00 a.m. every morning, he usually returns at around 7:00 p.m. I never really questioned his schedule when I was a child, but as I entered high school I wondered how my dad could work so hard every day of the week and still enjoy what he does. He works long hours, becomes

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    Thousands of food additives are widely used in food processing and people consume daily a considerable amount of these additives. Monosodium glutamate (MSG) is the sodium salt of glutamic acid, an abundant naturally occurring amino acid (Walker et al., 2000). It can produce a unique taste, known as a fifth taste (umami) that cannot be provided by other basic taste. MSG has also the ability to enhance diet intake in older (Bellisle, 1998; Yamaguchi, 1998; Yamaguchi and Ninomiya, 2000). This popular

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    G protein-coupled receptors (GPCRs) are the largest class of transmembrane receptors, and collectively they respond to diverse stimuli to regulate nearly all physiological processes. Consequently, GPCRs are considered attractive drug targets, and drugs with agonistic, antagonistic, and modulating properties at GPCRs have been developed to prevent or treat numerous diseases and disease symptoms. Over the past decade, technical advances in the fields of pharmacology, physiology, and structural biology

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    Introduction: There is immense study on the role of glutamate in Schizophrenia. Even so to date the current antipsychotics do not control major glutamatergic action albeit a study at the NMDA receptor location such as the glycine transport inhibitors may give new novel evidence for the discovery of future antipsychotics (Olney et al., 1999) The Dopamine hypothesis of Schizophrenia The dopamine (DA) theory of schizophrenia has subjugated the effort to justify the behaviours Schizophrenia is a psychiatric

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    Glial Cell Case Study

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    release of neurotransmitters from the presynaptic neuron. After its release from the presynaptic cell, the neurotransmitter diffuses across the synaptic cleft to the postsynaptic membrane, where it attaches to the receptor. 6. What are the differences between ionotropic and metabotropic

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    ganglion cells or amacrine cells. The transduction pathway in the bipolar cell is different from the photoreceptor transduction pathway in that there are two distinct bipolar cells that do not use photons as the trigger but instead the neurotransmitter glutamate that is activated by hyperpolarization of the photoreceptors. ON-bipolar cells are depolarized by a central stimuli to the receptive field that is position in the center while OFF-bipolar cells are hyperpolarized by

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    Learning refers to a process by which new information about the world is acquired, while memory describes how knowledge is retained. Memory can be explicit or implicit. In explicit form, there is conscious recall of information about things, people and places, while in implicit type, there is non-conscious recall of tasks such as motor skills(Broadbent et al., 2004). Explicit memory depends on the integrity of structures such as the hippocampus, subiculum, and entorhinal cortex. Implicit memory

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    Glutamate Case Study

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    Glutamate – An Excitatory Neurotransmitter Neurotransmitters are essential for transferring information between neurons and are released from a presynaptic terminal into a synaptic cleft. When the neurotransmitters bind to the postsynaptic receptors (specialized protein molecules that capture and react to molecules of the neurotransmitter), it induces an ionic flux which depolarizes the neuron. Neurotransmitter binding may also cause metabolic changes such as the activation of secondary messenger

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    Lou Gehrig's Disease

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    Lou Gehrig's disease is often referred to as Amyotrophic lateral sclerosis (ALS), this is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons come from the brain to the spinal cord and from the spinal cord to the muscles throughout the entire body. The progressive degeneration of the motor neurons in ALS would eventually leads to their death. When the motor neurons die, the ability of the brain to initiate and control muscle movement is

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    Potentiation) is responsible for the development of dendrites and spine (Stephan, Baldeweg, and Friston 2006). Altered function of the gene NRG1 that encodes neuregulin-1 and its receptor ErbB4 are also associated with the disease. High levels of NRG1 is observed in forebrain regions of patients with reduced activity of glutamate and GABA. Lin Mei and Wen-Cheng Xiong were able to observe behavioral deficits when they increased the levels of NRG1 of genetically engineered adult mice and they were also

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