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Free Drug development Essays and Papers

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    Drug Development

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    Drug development This entire section on drug development highlights concerns which are very particular to the industry. They therefore lead to the implementation of CSR activities which are also very industry specific, although aspects such as animal testing and ethics in research can be shared by other industries such as the cosmetics industry, or the medical device sector for instance. Need for R&D and innovation Today, the need for R&D and innovation is great, maybe greater than ever. In the

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    Drug Discovery, Development, and Manufacturing

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    Drug Discovery, Development, and Manufacturing The process of producing a new drug into the market involves drug discovery, drug development, and drug manufacturing. Pharmacokinetics and pharmacodynamics are both properties responsible for bringing about a new drug. Pharmacokinetics is the study of what the body does to a drug and of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the study of what a drug does to the body. It is the relationship of the resulting effect

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    Drug Development: Historical Influences, Recent Trends and Emerging Fields within the Pharmaceutical Industry Introduction In recent years, the cost of drug development has been rising at an unprecedented level. The cost of developing a new drug target was estimated to be $802 million in 2003, having risen from $138 million in 1979 and $318 million in 1991 [1] [2] [3]. These numbers are averages within the industry for the “average drug”. There is variation within the industry with cost estimates

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    DEVELOPMENT OF AN EASY, SAFE AND EFFECTIVE METHOD TO IDENTIFY DRUG INCOMPATIBILITIES INTRODUCTION Drug therapy is a complex process with innumerable parameters modulating its success and safety. The most vulnerable patients at risk of increased drug errors are those who require intensive care treatment. In such patients, multiple co-morbidity and multiorgan failure are frequent, with increasing mortality rate, oral drug treatment is often impossible in the initial phase of ICU admission. Making

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    Early-Phase Development Table of Contents 1. Introduction 1 1.1 Background 1 1.2 GSK Supply Chain 2 1.3 Demand Generation Process 4 1.4 Objective and Scope of Work 6 2. Literature Review 7 3. Methodology 11 4. Future Work 12 Figure 1 Clinical Development Process (Source: PhRMA) 1 Figure 2 GSK clinical trials supply chain 3 Figure 3 GSK clinical trial demand generation process 1. Introduction 1.1 Background In the pharmaceutical industry, the development process that

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    New Drug Reseach and Development in America

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    develop new drugs to combat serious diseases and disorders like cancer and depression. For many of these new drugs for diseases such as cancer, pharmaceutical companies spend around one billion dollars on research and development (Russell 23). Once a drug is developed in a lab, a lot of research needs to be conducted in real life scenarios to determine if the drug will work as it is designed. The most effective way to get accurate information is to run experiments to learn how the drug actually works

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    increasingly important in cancer treatments due to its contribution to the development of specific drugs. A variety of these signature markers has been discovered, such as the BCR-ABL oncogene in patients with Chronic Myeloid Leukaemia (CML). Although traditional therapies can be used in the treatment of a variety of cancers, it cannot kill the nature of this type. CML treatment requires a strategy by means of the combination of drugs in order to succeed in healing. Chronic Myeloid Leukaemia is a rare

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    Statistics show that an estimated 5.9 percent of women use drugs, 15.9 percent smoke cigarettes, and 8.5 percent drink alcohol at least once during pregnancy, according to a study conducted by the Substance Abuse and Mental Health Services Administration (2013). If drug and alcohol use by a pregnant woman continues and goes unnoticed by family members or doctors, the mental and physical development of their child has the potential to be extremely severe (Brady, Posner, Lang, Rosati, 1994). In this

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    BACKROUND The pharmaceutical industry's claim that high and increasing drug prices are needed to sustain research and development is a lie to the American public. Drug companies are spending more than twice as much on marketing, advertising, and administration than they do on research and development; that drug company profits, which are higher than all other industries, exceed research and development expenditures; and that drug companies provide lavish compensation packages for their top executives

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    Blockbuster drug sales produced large revenues for their companies leading this period of growth. However, events in recent history have begun to impact the industry and the future of pharmaceutical patents. The 2008 financial crisis significantly impacted growth as demand of medicine decreased. This economic recession, combined with multiple key blockbuster drug patents expiring in the last 4 years, changed and continues to impact the future of the pharmaceutical industry and new drug innovation

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