hereditary. One hereditary disease that can be particularly tragic is cystic fibrosis. Cystic fibrosis is a particularly fatal disease, it affects primarily young children and adolescents but a diagnosis later in life is not unheard of. “It is an inherited disease of the secretary glands” ("What is cystic," 2011) that can affect many of the body's organs, most characteristically the lungs. One of the reasons CF (the short form for cystic fibrosis) is so life-threatening is because of the amount of organs
Cystic fibrosis is a chronic, inherited, life threatening disease that affects organs in the body, because of sticky and thick mucus buildup on organs. The organs that are affected are the liver, lungs, pancreas, and intestine, which does damage to the respiratory, digestive and reproductive systems (Crosta). Cystic fibrosis is caused by a mutation in a gene called cystic fibrosis trans-membrane regulator, also called CFTR, which has an important function of creating sweat, mucus and digestive juices
Cystic fibrosis is a genetic disease; it is passed down through families. Cystic Fibrosis causes sticky mucus to build up in lungs, digestive track, and other areas of the body. The mucus clogs can lead to life threatening mucus infections. {Board, A.D.A.M. Editorial. Cystic fibrosis. U.S. National Library of Medicine, 16 May 2012. Web. 11 Jan. 2014.} Some of the most common symptoms of Cystic Fibrosis are salty skin, wheezing or shortness of breath, and persistent cough, sometimes with thick mucus
Cystic Fibrosis Results from Mutations in the genes encoding the cystic fibrosis trans membrane conductance regulator. This protein product is a traffic ATPase and C1 channel which localizes to the apical membrane of airway Epithelial. Breaking it down, Cystic Fibrosis is the most deadly common inherited disease affecting Caucasians in the United States. Cystic Fibrosis is a disorder that causes a thick and very sticky mucus to build up in the lungs and digestive tracks. Normally mucus
Cystic Fibrosis and Gene Therapy The average life span of a person with Cystic Fibrosis is 25-30 years of age. Although the more traditional treatments of this disease are adequate, is there something else that could be even better? Gene therapy is fast becoming one of the more studied aspects of genetics today. Let's take a look at some details of Cystic Fibrosis and gene therapy. Technical Aspects Cystic Fibrosis (CF) is the most common fatal genetic disease in the United States today
Cystic fibrosis, also known as CF, affects over 30,000 children and adults world-wide. CF is a disease in the lungs and digestive system and is still incurable today. It is a disease that causes thick, abnormal mucus in the lungs, nasal polyps, fatigue, and can also damage organs in a person’s body. According to www.cff.org/aboutcf, over 70% of CF patients are diagnosed at two years of age. Cystic fibrosis is one of the most life-threatening diseases in the United States and is very common amongst
Gene Therapy for Cystic Fibrosis Modern molecular genetics has given hopes and heartaches to thousands of people around the world. These people are looking towards gene therapy for an answer to their questions. To some people such as NIH director Harold Varmus the answer is a better understanding of basic genetic research and to others the answer is a cure, a hope, that their lethal disease will someday be cured. This essay touches on the background of gene therapy for Cystic Fibrosis (CF), current
Cystic Fibrosis (CF) is the most common life threatening genetic condition in Australia. CF affects many of the body’s systems, including lungs and digestion. Improved medication and treatments have seen life expectancy extend considerably. (Cystic Fibrosis Queensland, 2014) In Australia, CF is one of the most widespread genetic disorders, particularly in the younger population. According to recent statistics – roughly, one baby is diagnosed with CF every four days, and approximately 50% of children
Desiree Smith 30104997 Cystic Fibrosis Cystic Fibrosis is an inherited disease characterized by the buildup of thick, sticky mucous that can cause severe damage to the body’s organs. Mucous is usually a slippery substance that lubricates and protects the linings of the airway, digestive system, reproductive system and other organs and tissue. Problems with digestion can lead to diarrhea, malnutrition, poor growth, and weight-loss. Due to the abnormally thick mucous it can can clog airways, leading
Cystic Fibrosis (CF) Pathophysiology: Cystic fibrosis is a genetic disease of the secretory glands that affects the respiratory and digestive system. It mainly effects the lungs, pancreas, liver, intestines, sinuses, and reproductive organs. Cystic fibrosis effects the cells that produce sweat, mucus, and digestive fluids. Mucus becomes thick and sticky causing build-up in the lungs and blocking airways; making it easier for bacteria to develop. This prompts repeated lung infections and can cause
Cystic Fibrosis is an autosomal recessive genetic disease affecting the exocrine glands and progressively gets worse over time. The production of unusually thick mucus is formed causing blockages of the pancreatic ducts, intestines, and bronchi. Though it majorly affects the respiratory and digestive systems, sweat glands and the reproductive system are affected too. “The result is malnutrition, poor growth, numerous respiratory infections and breathing difficulties” (Interactive Health Tutorials:
A First Look at Cystic Fibrosis… One of the most chronic lung diseases which is becoming more and more apparent in typical young children around the world, though mostly Europe, and is somewhat apparent in adults is the genetic disease, Cystic Fibrosis (CF). The name itself comes from the genetically mutated protein that is known as Cystic Fibrosis trans-membrane conductance regulator (CFTR). The disease was first introduced and thoroughly explained by Dr. Dorothy Andersen in 1938. She brilliantly
Cystic Fibrosis (CF) is a very common, potentially life threatening condition. The disease is caused by inheritance, and affects the exocrine glands of the patient. Cystic fibrosis is found primarily among Caucasians and those of European descent. Those diagnosed with Cystic Fibrosis battle daily to perform simple tasks, such as breathing, as the mucus in their bodies thickens immensely. This mucus will potentially accumulate in the patient’s vital organs, such as the lungs, pancreas, and intestines
While cystic fibrosis (CF) is not a new disease, there is still a lot to learn about it. In 1938 a pathologist, Dr Dorothy Andersen, provided the first clear description of cystic fibrosis. Before this time there had been reports of people that had the symptoms of someone with CF. During the seventeenth century children with the symptoms of CF were thought to be bewitched and their life expectancy was very short. Dr Dorothy Andersen gave this disease its name because cystic fibrosis refers to the
In cystic fibrosis, a genetical condition that has a high population of young patients with multiple medical treatment requirements, it is of clinical importance to ensure compliance to their treatments in order to avoid a premature death. Behavioural economics can help here by addressing how we improve motivation with and perceived value of medical treatments – to improve overall patient compliance. In treatment compliance with children, up to 70% of patients with chronic illnesses have poor adherence
“Cystic Fibrosis in Adults: From Researcher to Practitioner” written by Gregory P. Marelich and Carroll E. Cross discusses the in depth details of cystic fibrosis. Gregory Marelich is a Doctor of Medicine (M.D.) and has certifications in internal medicine, pulmonary disease, and critical care medicine. Carroll Cross is a Doctor of Medicine and a Bachelor of Arts (B.A.). She is certified in pulmonary disease and internal medicine. Both authors have experience working in multiple facilities in California
Cystic Fibrosis is one of the most common genetically inherited diseases affecting white men and women. Cystic fibrosis is a genetic disorder where abnormal amounts of mucus build up in many of the body’s organs especially the lungs and the pancreas. This build up of mucus in the lungs can lead to many persistent infections that can lead to damage and scarring over time. In addition, when this mucus collects in the gastrointestinal tract and around the pancreas it prevents digestive juices from aiding
Cystic fibrosis (CF) is a disease that is caused by a defective gene that is inherited from both parents. The defective gene causes a person’s body to release thick sticky mucus which subsequently causes the patient’s airways to be blocked. Cystic fibrosis is a chronic respiratory disease with typical symptoms being digestion, wheezing, lung infection, stuffy nose, and a persistent cough. In 1938 an American Pathologist, Dr. Dorothy Anderson, was the first to identify and document cystic fibrosis
Cystic Fibrosis About 1,000 new cases of cystic fibrosis are diagnosed each year and over 70,000 people are already diagnosed worldwide. Cystic Fibrosis is a genetic disorder that affects the lungs’ ability to secrete mucus properly. It’s gene and protein product cause the body to produce unusually thick and sticky mucus (CFF). Mucus is designed to lubricate the lungs, but the lungs of a patient with cystic fibrosis are prone to infection because of the thick mucus that traps bacteria and foreign
Cystic Fibrosis Cystic fibrosis is a life-threatening disease that causes damage to the lungs and digestive system. This disease is constantly being researched to find a cure and to develop different treatments to lessen the disease’s effects. CF causes a multitude of defects to how a person’s body functions because of the gene mutation they are born with. To develop CF, a child must receive one gene mutation from each parent. According to the Cystic Fibrosis Foundation, “each time two