Introduction Osteoarthritis (OA) is the most common form of arthritis affecting at least 20 million Americans with its prevalence expected to double in the next 2 decades (12.) (9). OA was once believed to be a consequence of aging, which still holds true, but is now believed to involve a multitude of biological and pathological processes influenced by several factors, including genetics, age, gender, obesity, joint injury, estrogen, diabetes and muscle strength with age and weight being the predominating
angiogenesis and leukocyte infiltration in the joints (https://www.ncbi.nlm.nih.gov/pubmed/15180890) . Angiogenesis in the synovial lining can be a key factor in treating arthritis 8. Make medication cards for (due on 9/28 at 0800): glucosamine, celecoxib, methotrexate, leflunomide, meloxicam 9. Formulate a Nursing Care plan (3-part statement incl R/T and WEB) for a client with RA With one short-term/one long-term goal, at least 4 nursing interventions with scientific
Introduction- What is Etoricoxib? Etoricoxib, also known as Arcoxia1, is more commonly known as a non-steroidal anti-inflammatory drug (NSAID), or as a cyclo-oxygenase-2 inhibitor (COX-2). Therapeutically, it is specified for the ‘symptomatic relief” of conditions such as osteoarthritis (OA), rheumatoid arthritis (RA), ankylosing spondylitis2,3, and overall for their analgesic and anti-inflammatory properties. Arthritis is a chronic disease affecting up to ten million people in the UK. Approximately
of prostaglandins whereas COX-2 is responsible for production of additional prostaglandins when the body is injured as a natural defensive response. Non-selective NSAIDs, such as Ibuprofen, inhibit both COX-1 and COX-2 whereas selective NSAIDs; Celecoxib and Etoricoxib, inhibit only COX-2 (Society for Endocrinology, 2013; Ogbru, 2009). Ibuprofen is partially absorbed in the stomach and further ... ... middle of paper ... ...Formulary (BNF). (65th Ed.). London: BMJ Group and Pharmaceutical Press
The Pathways of Pain In 1931, the French medical missionary Dr. Albert Schweitzer wrote, "Pain is a more terrible lord of mankind than even death itself." Today, pain has become the universal disorder, a serious and costly public health issue, and a challenge for family, friends, and health care providers who must give support to the individual suffering from the physical as well as the emotional consequences of pain (1). Early humans related pain to evil, magic, and demons. Relief of pain