According to Lu and Bludau, the brain is partitioned into four lobes: frontal, temporal, parietal, and occipital. The frontal lobe formulates major decisions, such as planning, thinking, problem solving, organizing, and executing movements. It is located at the front of the brain. The temporal lobe is positioned under the frontal and parietal lobe. It generates and stores memories. It also coordinates the senses of taste, sound, and smell. The location of the parietal lobe is behind the frontal lobe. Parietal lobe controls sensation and perception sensory information such as smell and touch. The occipital lobe is located at the back of the brain. Its primary function is vision.
The brain functions through a system of “chemical and electrical processes” (Lu & Bludua, 2011), which is carried out by neurons (nerve cells). Neurons have the responsibility of producing memories and thinking. The eyes, ears, and nose process and obtain information, which also signals muscle movement. According to Lu and Bludau, a neuron transmits, processes, and generates information. Alzheimer’s hinders neuron’s hardware by breaking it down; neurons contain support cells called glial cells, mother cells, Glial cells manipulate assistance and nourishment. Glial cells “act as insulation” (Lu & Bludua, 2011) to keep neurons in place, to provide nutrients, clean up cellular debris, and dispose of damaged cells in the brain.
Capillaries are a “complex network of blood vessels in the brain” (Lu & Bludua, 2011). Capillaries consume twenty percent of the body’s blood supply. An axon, multiple dendrites, and a cell body manufacture a neuron. Axon “transmits messages to neighboring neurons, which branches out from the cell body” (Lu & Bludua, 2011), and faci...
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...rons disable and cannot function normally. Over time, the influence of amyloid plaques and neurofibrillary tangles trigger the neurons to immobilize the ability to communicate.
With progression of the disease, brain atrophy, shrinking parts of the brain, occurs in the late stages of Alzheimer’s. Alzheimer’s starts in the entorhinal cortex, deep in the brain beside the hippocampus. When amyloid plaques deposit between neurons, neurofibrillary tangles formation discontinues, which triggers the neurons to expire. Next Alzheimer’s proliferates to the hippocampus, which instigates forgetfulness. When the disease expands from the hippocampus, tangles and plaques spread throughout the brain affecting all areas, which results in the brain shriveling up. When brain tissue shrinks, ventricles, spaces in the brain, fill up with fluid. Ultimately, the brain and body expire.
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